| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 2073 |
Name | ERCC5 |
Synonymous | COFS3|ERCM2|UVDR|XPG|XPGC;excision repair cross-complementing rodent repair deficiency, complementation group 5;ERCC5;excision repair cross-complementing rodent repair deficiency, complementation group 5 |
Definition | DNA excision repair protein ERCC-5|DNA repair protein complementing XP-G cells|XPG-complementing protein|xeroderma pigmentosum, complementation group G |
Position | 13q33 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | XPG(h) + NTH1(h) <==> XPG(h):NTH1(h) (binding) | XPG(h) + PCNA(h) <==> XPG(h):PCNA(h) (binding) | XPG(h) + RPA116(h) + TFIIH-p62(h) + TFIIH-p90(h) + CSB(h) <==> XPG(h):RPA116(h):TFIIH-p62(h):TFIIH-p90(h):CSB(h) (binding) | NTH1(h) + XPG(h) <==> NTH1(h):XPG(h) (binding) | ERCC5(h) --> XPG(h) (expression). | NTH1(h) + XPG(h) <==> NTH1(h):XPG(h) (binding) | ERCC5(h) --> XPG(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 156 | Phosphoserine. | Swiss-Prot 53.0 | 157 | Phosphoserine. | Swiss-Prot 53.0 | 338 | Phosphothreonine. | Swiss-Prot 53.0 | 341 | Phosphoserine. | Swiss-Prot 53.0 | 355 | Phosphoserine. | Swiss-Prot 53.0 | 356 | Phosphoserine. | Swiss-Prot 53.0 | 357 | Phosphoserine. | Swiss-Prot 53.0 | 384 | Phosphoserine. | Swiss-Prot 53.0 | 428 | Phosphoserine. | Swiss-Prot 53.0 | 526 | Phosphoserine. | Swiss-Prot 53.0 | 563 | Phosphoserine. | Swiss-Prot 53.0 | 705 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 724 | Phosphoserine. | Swiss-Prot 53.0 | 357 | Phosphoserine | 15302935;17081983 | Phospho.ELM 6.0 | 526 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 563 | Phosphoserine | 15302935;17081983 | Phospho.ELM 6.0 | 428 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 384 | Phosphoserine | 15302935;17081983 | Phospho.ELM 6.0 | 338 | Phosphothreonine | 15302935 | Phospho.ELM 6.0 | 341 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 355 | Phosphoserine | 15302935;17081983 | Phospho.ELM 6.0 | 356 | Phosphoserine | 15302935;17081983 | Phospho.ELM 6.0 | 156 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 157 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 562 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr13 |
Promoter: 102294675 - 102296675 | Agilent_014791 |
chr13 |
Promoter: 102294675 - 102296675 | GSE27584 |
chr13 |
Promoter: 102294675 - 102296675 | Agilent_014791_44K |