Entrez Gene

Pediatric cancer gene database (Pedican) Home

General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information
Gene ID	2073
Name	ERCC5
Synonymous	COFS3\|ERCM2\|UVDR\|XPG\|XPGC;excision repair cross-complementing rodent repair deficiency, complementation group 5;ERCC5;excision repair cross-complementing rodent repair deficiency, complementation group 5
Definition	DNA excision repair protein ERCC-5\|DNA repair protein complementing XP-G cells\|XPG-complementing protein\|xeroderma pigmentosum, complementation group G
Position	13q33
Gene Type	protein-coding
Gene Interactions:	Physical Interaction Metabolic Interaction Signaling Interaction

Interaction Type	Interactor	Data Source
Physical Interaction [Top]
in same component	CCNH	REACTOME;
in same component	CDK7	REACTOME;
in same component	DDB1	REACTOME;
in same component	DDB2	REACTOME;
in same component	ERCC1	REACTOME;
in same component	ERCC2	REACTOME;
in same component	ERCC3	REACTOME;
in same component	ERCC4	REACTOME;
in same component	ERCC6	REACTOME;
in same component	ERCC8	REACTOME;
in same component	GTF2H1	REACTOME;
in same component	GTF2H2	REACTOME;
in same component	GTF2H3	REACTOME;
in same component	GTF2H4	REACTOME;
in same component	MNAT1	REACTOME;
in same component	RAD23B	REACTOME;
in same component	RPA1	REACTOME;
in same component	RPA2	REACTOME;
in same component	RPA3	REACTOME;
in same component	TCEA1	REACTOME;
in same component	XAB2	REACTOME;
in same component	XPA	REACTOME;
in same component	XPC	REACTOME;
interacts with	CDK7	BIOGRID;
interacts with	ERCC2	BIOGRID;
interacts with	ERCC2	HPRD;
interacts with	ERCC3	BIOGRID;
interacts with	ERCC6	HPRD;
interacts with	EWSR1	MINT;
interacts with	GTF2H1	HPRD;
interacts with	NTHL1	BIOGRID;
interacts with	NTHL1	HPRD;
interacts with	PCNA	BIOGRID;
interacts with	PCNA	HPRD;
interacts with	POLR2A	HPRD;
interacts with	TAF10	BIOGRID;

Interaction Type	Interactor	Data Source
Metabolic Interaction [Top]
sequential catalysis	CCNH	REACTOME;
sequential catalysis	CDK7	REACTOME;
sequential catalysis	ERCC1	REACTOME;
sequential catalysis	ERCC2	REACTOME;
sequential catalysis	ERCC3	REACTOME;
sequential catalysis	ERCC4	REACTOME;
sequential catalysis	ERCC5	REACTOME;
sequential catalysis	ERCC6	REACTOME;
sequential catalysis	ERCC8	REACTOME;
sequential catalysis	GTF2H1	REACTOME;
sequential catalysis	GTF2H2	REACTOME;
sequential catalysis	GTF2H3	REACTOME;
sequential catalysis	GTF2H4	REACTOME;
sequential catalysis	MNAT1	REACTOME;
sequential catalysis	TCEA1	REACTOME;
sequential catalysis	XAB2	REACTOME;

Interaction Type	Interactor	Data Source
Signaling Interaction [Top]
reacts with	CCNH	REACTOME;
reacts with	CDK7	REACTOME;
reacts with	DDB1	REACTOME;
reacts with	DDB2	REACTOME;
reacts with	ERCC1	REACTOME;
reacts with	ERCC2	REACTOME;
reacts with	ERCC3	REACTOME;
reacts with	ERCC4	REACTOME;
reacts with	ERCC5	REACTOME;
reacts with	ERCC6	REACTOME;
reacts with	ERCC8	REACTOME;
reacts with	GTF2H1	REACTOME;
reacts with	GTF2H2	REACTOME;
reacts with	GTF2H3	REACTOME;
reacts with	GTF2H4	REACTOME;
reacts with	MNAT1	REACTOME;
reacts with	POLR2A	REACTOME;
reacts with	POLR2B	REACTOME;
reacts with	POLR2C	REACTOME;
reacts with	POLR2D	REACTOME;
reacts with	POLR2E	REACTOME;
reacts with	POLR2H	REACTOME;
reacts with	POLR2I	REACTOME;
reacts with	POLR2J	REACTOME;
reacts with	POLR2K	REACTOME;
reacts with	RAD23B	REACTOME;
reacts with	RPA1	REACTOME;
reacts with	RPA2	REACTOME;
reacts with	RPA3	REACTOME;
reacts with	TCEA1	REACTOME;
reacts with	XAB2	REACTOME;
reacts with	XPA	REACTOME;
reacts with	XPC	REACTOME;
state change	CCNH	REACTOME;
state change	CDK7	REACTOME;
state change	DDB1	REACTOME;
state change	DDB2	REACTOME;
state change	ERCC1	REACTOME;
state change	ERCC2	REACTOME;
state change	ERCC3	REACTOME;
state change	ERCC4	REACTOME;
state change	ERCC5	REACTOME;
state change	GTF2H1	REACTOME;
state change	GTF2H2	REACTOME;
state change	GTF2H3	REACTOME;
state change	GTF2H4	REACTOME;
state change	MNAT1	REACTOME;
state change	RAD23B	REACTOME;
state change	RPA1	REACTOME;
state change	RPA2	REACTOME;
state change	RPA3	REACTOME;
state change	XPA	REACTOME;
state change	XPC	REACTOME;

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