Entrez Gene

Basic Information
Gene ID	4233
Name	MET
Synonymous	AUTS9\|HGFR\|RCCP2\|c-Met;met proto-oncogene (hepatocyte growth factor receptor);MET;met proto-oncogene (hepatocyte growth factor receptor)
Definition	HGF receptor\|HGF/SF receptor\|SF receptor\|hepatocyte growth factor receptor\|met proto-oncogene tyrosine kinase\|oncogene MET\|proto-oncogene c-Met\|scatter factor receptor\|tyrosine-protein kinase Met
Position	7q31
Gene Type	protein-coding
Gene Mutation:	PCGP germline mutation PCGP somatic mutation COSMIC somatic mutation

PCGP germline mutation [Top]
	There is no record for MET

Variant (Variant; Chr; Position)	Genotype (MutationType; MutationClass; ReferenceAllele; Genotype; Origin)	Disease (CancerType; ValidationStatus; SequencingType)
PCGP somatic mutation [Top]
MET_R412H; chr7; 116371756	SUB; MISSENSE; G; G/A; SOMATIC	RHB; PUTATIVE-HQ; TARGETED_SEQUENCING

Mutation (CDS; AA; Chr)	Site	Histology
COSMIC somatic mutation [Top]
c.2942-27_2942-6del22; p.?; 7:116199112-116199133	lung	carcinoma; adenocarcinoma
c.3062_3082+7del28; p.?; 7:116199259-116199286	lung	carcinoma; adenocarcinoma
c.3376G>K; p.A1126S; 7:116204741-116204741	lung	carcinoma; squamous_cell_carcinoma
c.2923A>T; p.K975*;	breast	carcinoma; HER-positive_carcinoma
c.547A>G; p.K183E;	liver	carcinoma; hepatocellular_carcinoma
c.3082+1G>A; p.?; 7:116199280-116199280	lung	carcinoma; adenocarcinoma
c.2942_3082del141; p.982_1028del47; 7:116199123-116202174	lung	carcinoma; adenocarcinoma
c.2942_3082del141; p.982_1028del47; 7:116199092-116199111	lung	carcinoma; adenocarcinoma
c.2942_3082del141; p.L982_D1028del47; 7:116199139-116199279	lung	carcinoma; adenocarcinoma
c.2942_3082del141; p.L982_D1028del47; 7:116199139-116199279	lung	carcinoma; adenocarcinoma
c.2942-18_2942-8delctttctctctg; p.?; 7:116199121-116199131	lung	carcinoma; adenocarcinoma
c.2942_3082del141; p.L982_D1028del47; 7:116199139-116199279	lung	carcinoma; adenocarcinoma
c.3803T>C; p.M1268T; 7:116210710-116210710	kidney	carcinoma; papillary_renal_cell_carcinoma
c.2942_3082del141; p.982_1028del47;	lung	carcinoma; non_small_cell_carcinoma
c.2942_3082del141; p.Q1029_G1105del;	lung	carcinoma; non_small_cell_carcinoma
c.2942_3082del141; p.982_1028del47;	lung	carcinoma; non_small_cell_carcinoma
c.?; p.T230M;	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.?; p.E168D;	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.?; p.T1010I;	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.?; p.T1010I;	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.?; p.T1010I;	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.?; p.T1275I;	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.?; p.V1333I;	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3029C>T; p.T1010I; 7:116199226-116199226	thyroid	carcinoma; anaplastic_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.?; p.N375S;	lung	carcinoma; non_small_cell_carcinoma
c.?; p.N375S;	lung	carcinoma; non_small_cell_carcinoma
c.?; p.N375S;	lung	carcinoma; non_small_cell_carcinoma
c.?; p.N375S;	lung	carcinoma; non_small_cell_carcinoma
c.?; p.N375S;	lung	carcinoma; non_small_cell_carcinoma
c.?; p.N375S;	lung	carcinoma; non_small_cell_carcinoma
c.?; p.N375S;	lung	carcinoma; non_small_cell_carcinoma
c.?; p.N375S;	lung	carcinoma; non_small_cell_carcinoma
c.?; p.N375S;	lung	carcinoma; non_small_cell_carcinoma
c.?; p.N375S;	lung	carcinoma; non_small_cell_carcinoma
c.?; p.N375S;	lung	carcinoma; non_small_cell_carcinoma
c.?; p.N375S;	lung	carcinoma; non_small_cell_carcinoma
c.?; p.N375S;	lung	carcinoma; non_small_cell_carcinoma
c.?; p.N375S;	lung	carcinoma; non_small_cell_carcinoma
c.?; p.L211W;	lung	carcinoma; non_small_cell_carcinoma
c.3331T>A; p.Y1111N;	liver	carcinoma; hepatocellular_carcinoma
c.3230A>G; p.N1077S;	skin; face	malignant_melanoma
c.?; p.H150Y;	NS	carcinoma
c.?; p.C385Y;	NS	carcinoma
c.?; p.E168D;	NS	carcinoma
c.?; p.Q142*;	NS	carcinoma
c.?; p.T1010I;	NS	carcinoma; adenocarcinoma
c.?; p.E168D;	NS	carcinoma
c.?; p.V1312I;	NS	carcinoma
c.?; p.G1137A;	pleura	mesothelioma
c.?; p.S203T;	pleura	mesothelioma
c.3029C>T; p.T1010I; 7:116199226-116199226	lung	carcinoma; adenocarcinoma
c.3029C>T; p.T1010I; 7:116199226-116199226	lung	carcinoma; non_small_cell_carcinoma
c.?; p.G983S;	lung	carcinoma; non_small_cell_carcinoma
c.?; p.E168D;	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Langerhans_cell_histiocytosis
c.2942-20_2943del22; p.?; 7:116199119-116199140	lung	carcinoma; adenocarcinoma
c.3061T>A; p.Y1021N; 7:116199258-116199258	lung	carcinoma; adenocarcinoma
c.3778G>T; p.G1260C; 7:116210685-116210685	lung	carcinoma; adenocarcinoma
c.?; p.T1010I;	ovary	carcinoma
c.?; p.T1010I;	ovary	carcinoma
c.?; p.T1010I;	ovary	carcinoma
c.?; p.T1010I;	endometrium	carcinoma
c.?; p.T1010I;	skin	malignant_melanoma
c.3154A>G; p.I1052V;	eye; uveal_tract	malignant_melanoma; mixed
c.2962C>T; p.R988C;	lung	carcinoma; small_cell_carcinoma
c.2962C>T; p.R988C;	lung	carcinoma; small_cell_carcinoma
c.2986C>T; p.P996S;	lung; left_lower_lobe	carcinoma; small_cell_carcinoma
c.3029C>T; p.T1010I; 7:116199226-116199226	autonomic_ganglia; bladder	paraganglioma; malignant
c.3029C>T; p.T1010I; 7:116199226-116199226	lung	carcinoid-endocrine_tumour; typical
c.3029C>T; p.T1010I; 7:116199226-116199226	lung	carcinoid-endocrine_tumour; atypical
c.1829G>A; p.C610Y;	skin; neck	malignant_melanoma
c.1829G>A; p.C610Y;	skin; neck	malignant_melanoma
c.3029C>T; p.T1010I; 7:116199226-116199226	kidney	carcinoma
c.1124A>G; p.N375S; 7:116127498-116127498	kidney	carcinoma; clear_cell_renal_cell_carcinoma
c.3029C>T; p.T1010I; 7:116199226-116199226	kidney	carcinoma
c.3029C>T; p.T1010I; 7:116199226-116199226	kidney	carcinoma
c.?; p.T1010I;	biliary_tract; bile_duct	carcinoma; adenocarcinoma
c.?; p.T1010I;	breast	carcinoma; basal_(triple-negative)_carcinoma
c.?; p.Y1248C;	skin; mucosal	malignant_melanoma
c.?; p.T1010I;	biliary_tract; bile_duct	carcinoma; adenocarcinoma
c.3563G>A; p.R1188Q;	skin; upper_leg	malignant_melanoma
c.673G>A; p.G225S;	NS	malignant_melanoma
c.673G>A; p.G225S;	NS	malignant_melanoma
c.3736G>C; p.D1246H; 7:116210643-116210643	kidney	carcinoma; papillary_renal_cell_carcinoma
c.3742T>C; p.Y1248H; 7:116210649-116210649	kidney	carcinoma; papillary_renal_cell_carcinoma
c.3803T>C; p.M1268T; 7:116210710-116210710	kidney	carcinoma; papillary_renal_cell_carcinoma
c.3803T>C; p.M1268T; 7:116210710-116210710	kidney	carcinoma; papillary_renal_cell_carcinoma
c.3334C>T; p.H1112Y; 7:116204699-116204699	kidney	carcinoma; papillary_renal_cell_carcinoma
c.3637C>G; p.L1213V; 7:116209338-116209338	kidney	carcinoma; papillary_renal_cell_carcinoma
c.1201-1G>T; p.?;	lung	carcinoma; small_cell_carcinoma
c.3550C>T; p.R1184*;	large_intestine; colon	carcinoma; adenocarcinoma
c.576C>A; p.F192L;	large_intestine; colon	carcinoma; adenocarcinoma
c.1997A>G; p.Y666C;	large_intestine; colon	carcinoma; adenocarcinoma
c.3562C>T; p.R1188*;	large_intestine; colon	carcinoma; adenocarcinoma
c.3743A>G; p.Y1248C; 7:116210650-116210650	kidney	other; neoplasm
c.3370C>G; p.H1124D; 7:116204735-116204735	kidney	carcinoma; papillary_renal_cell_carcinoma
c.3335A>T; p.H1112L; 7:116204700-116204700	kidney	carcinoma; papillary_renal_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3743A>G; p.Y1248C; 7:116210650-116210650	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3743A>G; p.Y1248C; 7:116210650-116210650	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3743A>G; p.Y1248C; 7:116210650-116210650	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3743A>G; p.Y1248C; 7:116210650-116210650	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3743A>G; p.Y1248C; 7:116210650-116210650	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3743A>G; p.Y1248C; 7:116210650-116210650	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3743A>G; p.Y1248C; 7:116210650-116210650	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3029C>T; p.T1010I; 7:116199226-116199226	thyroid	carcinoma; follicular_carcinoma
c.3029C>T; p.T1010I; 7:116199226-116199226	thyroid	carcinoma; papillary_carcinoma
c.687G>T; p.L229F; 7:116127061-116127061	lung	carcinoma; adenocarcinoma
c.2942_3082del141; p.L982_D1028del47; 7:116199139-116199279	lung	carcinoma; adenocarcinoma
c.1170C>T; p.Y390Y;	large_intestine	carcinoma; adenocarcinoma
c.3712G>A; p.V1238I;	kidney	carcinoma; clear_cell_renal_cell_carcinoma
c.1996T>C; p.Y666H;	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma
c.3646delA; p.K1217fs*49;	large_intestine	carcinoma; adenocarcinoma
c.997A>T; p.I333L;	large_intestine; colon	carcinoma; adenocarcinoma
c.3446T>C; p.M1149T; 7:116206117-116206117	kidney	carcinoma; papillary_renal_cell_carcinoma
c.3390G>A; p.L1130L; 7:116204755-116204755	testis	germ_cell_tumour
c.3352A>T; p.N1118Y; 7:116204717-116204717	large_intestine	carcinoma; adenocarcinoma
c.3335A>G; p.H1112R; 7:116204700-116204700	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.3626_3627CG>GC; p.A1209G; 7:116209327-116209328	ovary	carcinoma; mucinous_carcinoma
c.3803T>C; p.M1268T; 7:116210710-116210710	kidney	carcinoma; papillary_renal_cell_carcinoma
c.3410G>T; p.G1137V; 7:116206081-116206081	central_nervous_system; brain	glioma; oligodendroglioma
c.3572C>T; p.T1191I; 7:116206243-116206243	liver	carcinoma; hepatocellular_carcinoma
c.3804G>A; p.M1268I; 7:116210711-116210711	liver	carcinoma; hepatocellular_carcinoma
c.3785A>G; p.K1262R; 7:116210692-116210692	liver	carcinoma; hepatocellular_carcinoma
c.1802_1803insT; p.R602fs*1;	oesophagus	carcinoma; adenocarcinoma
c.4177G>A; p.A1393T;	oesophagus	carcinoma; adenocarcinoma
c.1584A>G; p.Q528Q;	oesophagus	carcinoma; adenocarcinoma
c.3053C>T; p.S1018F;	oesophagus; lower_third	carcinoma; adenocarcinoma
c.3912C>T; p.D1304D;	stomach	carcinoma; adenocarcinoma
c.4071G>A; p.A1357A;	stomach	carcinoma; adenocarcinoma
c.4146G>A; p.P1382P;	stomach	carcinoma; adenocarcinoma
c.2962C>T; p.R988C;	lung	carcinoma; small_cell_carcinoma
c.2962C>T; p.R988C;	lung	carcinoma; small_cell_carcinoma
c.?; p.N375S;	lung	carcinoma; non_small_cell_carcinoma
c.534C>T; p.S178S;	lung	carcinoma
c.3082+1G>T; p.?; 7:116199280-116199280	lung	carcinoma; mixed_adenosquamous_carcinoma
c.1912A>T; p.I638L;	lung	carcinoma; adenocarcinoma
c.3013C>G; p.R1005G;	liver	carcinoma
c.2713T>G; p.L905V;	liver	carcinoma
c.3083-1G>T; p.?; 7:116202170-116202170	breast	carcinoma; ductal_carcinoma
c.2067C>A; p.H689Q;	liver	carcinoma
c.858T>G; p.S286S;	liver	carcinoma
c.713delT; p.L238fs*25;	large_intestine; colon	carcinoma
c.710delT; p.L238fs*25;	large_intestine; colon	carcinoma; adenocarcinoma
c.2666A>C; p.K889T;	liver	carcinoma
c.2067C>A; p.H689Q;	liver	carcinoma
c.435C>G; p.V145V;	liver	carcinoma
c.3082+1G>T; p.?; 7:116199280-116199280	stomach	carcinoma
c.3082+1G>T; p.?; 7:116199280-116199280	stomach	carcinoma
c.?; p.N375S;	lung	carcinoma; adenocarcinoma
c.?; p.V370D;	lung	carcinoma; adenocarcinoma
c.?; p.R1000S;	NS	malignant_melanoma
c.?; p.N375S;	NS	malignant_melanoma
c.?; p.G983V;	NS	malignant_melanoma
c.142G>A; p.A48T;	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia
c.470A>G; p.E157G;	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia
c.4114G>C; p.A1372P;	lung	carcinoma; adenocarcinoma
c.3370C>G; p.H1124D; 7:116204735-116204735	lung	carcinoma; adenocarcinoma
c.3631delA; p.K1211fs*55;	lung	carcinoma; adenocarcinoma
c.3532A>T; p.M1178L;	lung	carcinoma; adenocarcinoma
c.1572G>A; p.Q524Q;	lung	carcinoma; adenocarcinoma
c.3062A>T; p.Y1021F;	lung	carcinoma; adenocarcinoma
c.6G>T; p.K2N;	lung	carcinoma; adenocarcinoma
c.2224C>G; p.P742A;	lung	carcinoma; adenocarcinoma
c.3257A>T; p.H1086L;	lung	carcinoma; adenocarcinoma
c.4077C>A; p.F1359L;	lung	carcinoma; adenocarcinoma
c.1930C>A; p.H644N;	lung	carcinoma; adenocarcinoma
c.3412_3413GA>AC; p.E1138T;	skin; trunk	malignant_melanoma
c.3029C>T; p.T1010I; 7:116199226-116199226	thyroid	carcinoma; follicular_carcinoma
c.468G>A; p.S156S; 7:116126842-116126842	large_intestine; colon	carcinoma; adenocarcinoma
c.849C>T; p.S283S; 7:116127223-116127223	lung	carcinoma; non_small_cell_carcinoma
c.2962C>T; p.R988C;	lung	carcinoma; small_cell_carcinoma
c.2962C>T; p.R988C;	lung	carcinoma; small_cell_carcinoma
c.748G>C; p.V250L;	bone	osteosarcoma
c.3497G>A; p.R1166Q;	ovary	carcinoma; serous_carcinoma
c.4027G>A; p.E1343K;	ovary	carcinoma; serous_carcinoma
c.1128G>A; p.K376K; 7:116127502-116127502	stomach	carcinoma; adenocarcinoma
c.918G>C; p.K306N;	breast	carcinoma
c.1814T>A; p.L605H;	central_nervous_system; brain	glioma; astrocytoma_Grade_IV
c.3484G>A; p.G1162R;	prostate	carcinoma
c.?; p.Q978L;	kidney	carcinoma; clear_cell_renal_cell_carcinoma
c.?; p.V136I;	kidney	carcinoma; clear_cell_renal_cell_carcinoma
c.?; p.Q978L;	kidney	carcinoma; clear_cell_renal_cell_carcinoma
c.2877A>G; p.I959M;	lung	carcinoma; small_cell_carcinoma
c.1371A>T; p.T457T;	lung	carcinoma; small_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.3757T>G; p.Y1253D; 7:116210664-116210664	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma
c.2638-1G>A; p.?;	breast	carcinoma; basal_(triple-negative)_carcinoma
c.1124A>G; p.N375S; 7:116127498-116127498	upper_aerodigestive_tract; head_neck	carcinoma
c.?; p.N375S;	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma
c.571C>T; p.R191W;	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia
c.3652T>G; p.F1218V;	kidney	carcinoma; clear_cell_renal_cell_carcinoma
c.3083-52insCT; p.?; 7:116202119-116202120	lung	carcinoma; small_cell_carcinoma
c.3083-52insCT; p.?; 7:116202119-116202120	lung	carcinoma; small_cell_carcinoma
c.3029C>T; p.T1010I; 7:116199226-116199226	lung	carcinoma; small_cell_carcinoma
c.504G>T; p.E168D; 7:116126878-116126878	lung	carcinoma; small_cell_carcinoma
c.1076G>A; p.R359Q;	autonomic_ganglia	neuroblastoma
c.3602G>A; p.G1201D;	autonomic_ganglia	neuroblastoma
c.3082+2T>C; p.?; 7:116199281-116199281	central_nervous_system; brain	glioma; astrocytoma_Grade_IV
c.3534G>C; p.M1178I; 7:116206205-116206205	central_nervous_system; brain	glioma; astrocytoma_Grade_IV
c.3534G>C; p.M1178I; 7:116206205-116206205	central_nervous_system; brain	glioma; astrocytoma_Grade_IV
c.2661A>C; p.A887A;	central_nervous_system; brain	glioma; astrocytoma_Grade_IV
c.2661A>T; p.A887A;	central_nervous_system; brain	glioma; astrocytoma_Grade_IV
c.1620G>A; p.W540*; 7:116168234-116168234	central_nervous_system; brain	glioma; astrocytoma_Grade_IV
c.1426C>T; p.H476Y;	lung	carcinoma; adenocarcinoma
c.2661A>G; p.A887A;	central_nervous_system; brain	glioma; astrocytoma_Grade_IV
c.2661A>G; p.A887A;	central_nervous_system; brain	glioma; astrocytoma_Grade_IV
c.662A>G; p.E221G; 7:116127036-116127036	ovary	carcinoma; serous_carcinoma
c.3668T>G; p.L1223W;	ovary	carcinoma; serous_carcinoma
c.3668T>G; p.L1223W;	ovary	carcinoma; serous_carcinoma
c.3668T>G; p.L1223W;	ovary	carcinoma; serous_carcinoma
c.4192G>A; p.D1398N; 7:116223379-116223379	ovary	carcinoma; serous_carcinoma
c.3341C>G; p.T1114S;	lung	carcinoma; squamous_cell_carcinoma
c.3282G>C; p.L1094L;	lung	carcinoma; squamous_cell_carcinoma
c.714A>T; p.L238F; 7:116127088-116127088	ovary	carcinoma; serous_carcinoma
c.798G>C; p.R266S; 7:116127172-116127172	ovary	carcinoma; serous_carcinoma
c.1695C>G; p.I565M;	lung	carcinoma; squamous_cell_carcinoma
c.944A>G; p.N315S;	lung	carcinoma; adenocarcinoma
c.1979C>G; p.T660R;	lung; middle_lobe	carcinoma; adenocarcinoma
c.3082+1G>T; p.?; 7:116199280-116199280	lung	carcinoma; adenocarcinoma
c.1322C>G; p.S441C;	lung; right_upper_lobe	carcinoma; adenocarcinoma
c.2637+1G>T; p.?;	lung; right_lower_lobe	carcinoma; adenocarcinoma
c.293G>T; p.C98F;	lung	carcinoma; adenocarcinoma
c.3995A>G; p.E1332G;	lung	carcinoma; adenocarcinoma
c.3757T>C; p.Y1253H;	lung	carcinoma; adenocarcinoma
c.2785-1G>C; p.?;	lung	carcinoma; squamous_cell_carcinoma
c.2092A>T; p.T698S;	lung	carcinoma; squamous_cell_carcinoma
c.1149G>T; p.V383V;	lung	carcinoma; squamous_cell_carcinoma
c.669A>G; p.K223K;	lung	carcinoma; adenocarcinoma
c.3082+2T>C; p.?; 7:116199281-116199281	lung	carcinoma; adenocarcinoma
c.3063C>G; p.Y1021*;	lung	carcinoma; adenocarcinoma
c.4019C>A; p.P1340H;	lung; right_lower_lobe	carcinoma; adenocarcinoma
c.1533G>T; p.T511T;	lung	carcinoma; squamous_cell_carcinoma
c.961T>C; p.Y321H;	lung; right_lower_lobe	carcinoma; adenocarcinoma
c.3082+1G>A; p.?; 7:116199280-116199280	lung; right_upper_lobe	carcinoma; adenocarcinoma
c.1278C>T; p.R426R;	lung; right_upper_lobe	carcinoma; adenocarcinoma
c.1393-2A>T; p.?;	kidney	carcinoma; clear_cell_renal_cell_carcinoma
c.37G>C; p.V13L;	large_intestine; colon	carcinoma; adenocarcinoma
c.3336T>C; p.H1112H;	large_intestine; colon	carcinoma; adenocarcinoma
c.2883A>C; p.T961T;	large_intestine; colon	carcinoma; adenocarcinoma
c.3785A>G; p.K1262R; 7:116210692-116210692	large_intestine; colon	carcinoma; adenocarcinoma
c.783C>A; p.F261L;	large_intestine; caecum	carcinoma; adenocarcinoma
c.3375T>C; p.C1125C;	large_intestine; colon	carcinoma; adenocarcinoma
c.674G>A; p.G225D;	breast	carcinoma
c.3573T>C; p.T1191T;	large_intestine; colon	carcinoma; adenocarcinoma
c.3352A>G; p.N1118D;	large_intestine; colon	carcinoma; adenocarcinoma
c.573G>A; p.R191R;	large_intestine; colon	carcinoma; adenocarcinoma
c.3573T>C; p.T1191T;	large_intestine; colon	carcinoma; adenocarcinoma
c.3757T>A; p.Y1253N;	large_intestine; colon	carcinoma; adenocarcinoma
c.2962C>A; p.R988S;	large_intestine; colon	carcinoma; adenocarcinoma
c.4010G>A; p.C1337Y;	large_intestine; colon	carcinoma; adenocarcinoma
c.3738C>T; p.D1246D;	large_intestine; colon	carcinoma; adenocarcinoma
c.3350A>G; p.D1117G;	large_intestine; colon	carcinoma; adenocarcinoma
c.683T>G; p.F228C;	large_intestine; caecum	carcinoma; adenocarcinoma
c.608C>A; p.S203Y;	large_intestine; colon	carcinoma; adenocarcinoma
c.1900T>C; p.F634L;	large_intestine; colon	carcinoma; adenocarcinoma
c.1618T>C; p.W540R;	large_intestine; colon	carcinoma; adenocarcinoma
c.796A>C; p.R266R;	large_intestine; colon	carcinoma; adenocarcinoma
c.3439_3441delATC; p.I1148delI;	large_intestine; colon	carcinoma; adenocarcinoma
c.3803T>C; p.M1268T; 7:116210710-116210710	large_intestine; colon	carcinoma; adenocarcinoma
c.638C>T; p.S213L;	large_intestine; rectum	carcinoma; adenocarcinoma
c.666G>A; p.T222T;	endometrium	carcinoma; endometrioid_carcinoma
c.770A>C; p.N257T;	endometrium	carcinoma; endometrioid_carcinoma
c.3360C>T; p.G1120G;	endometrium	carcinoma; endometrioid_carcinoma
c.62G>T; p.R21M;	endometrium	carcinoma; endometrioid_carcinoma
c.1406G>A; p.R469Q;	endometrium	carcinoma; endometrioid_carcinoma
c.3118C>T; p.R1040*;	endometrium	carcinoma; endometrioid_carcinoma
c.1076_1078delGAT; p.R359_S360>P;	breast	carcinoma
c.1081_1083delGCC; p.A361delA;	breast	carcinoma
c.1084_1085insT; p.M362fs*34;	breast	carcinoma
c.2389G>A; p.V797M;	breast	carcinoma
c.3784A>G; p.K1262E;	large_intestine	carcinoma; adenocarcinoma
c.2150C>A; p.S717*;	endometrium	carcinoma; endometrioid_carcinoma
c.3034G>T; p.E1012*;	endometrium	carcinoma; endometrioid_carcinoma
c.1285T>G; p.L429V;	endometrium	carcinoma; endometrioid_carcinoma
c.1234C>T; p.R412C;	endometrium	carcinoma; endometrioid_carcinoma
c.3143A>G; p.D1048G;	endometrium	carcinoma; endometrioid_carcinoma
c.467C>T; p.S156L;	large_intestine; caecum	carcinoma; adenocarcinoma
c.1336A>G; p.I446V;	large_intestine; caecum	carcinoma; adenocarcinoma
c.2489A>G; p.Q830R;	large_intestine; caecum	carcinoma; adenocarcinoma
c.3743A>G; p.Y1248C; 7:116210650-116210650	large_intestine; colon	carcinoma; adenocarcinoma
c.503A>G; p.E168G;	large_intestine; colon	carcinoma; adenocarcinoma
c.203A>G; p.N68S;	kidney	carcinoma; clear_cell_renal_cell_carcinoma
c.1276C>T; p.R426C;	kidney	carcinoma; clear_cell_renal_cell_carcinoma
c.3667T>G; p.L1223V;	kidney	carcinoma; clear_cell_renal_cell_carcinoma
c.639G>A; p.S213S;	endometrium	carcinoma; endometrioid_carcinoma
c.918G>T; p.K306N;	endometrium	carcinoma; endometrioid_carcinoma
c.3592G>T; p.D1198Y;	endometrium	carcinoma; endometrioid_carcinoma
c.187T>G; p.F63V;	endometrium	carcinoma; endometrioid_carcinoma
c.499G>A; p.E167K;	endometrium	carcinoma; endometrioid_carcinoma
c.3271C>T; p.P1091S;	endometrium	carcinoma; endometrioid_carcinoma
c.3376G>T; p.A1126S;	endometrium	carcinoma; endometrioid_carcinoma
c.1234C>G; p.R412G;	breast	carcinoma
c.639G>A; p.S213S;	endometrium	carcinoma; endometrioid_carcinoma
c.4113C>T; p.N1371N;	endometrium	carcinoma; endometrioid_carcinoma
c.788C>T; p.T263M;	endometrium	carcinoma; endometrioid_carcinoma
c.909G>T; p.K303N;	endometrium	carcinoma; endometrioid_carcinoma
c.4077C>T; p.F1359F;	urinary_tract; bladder	carcinoma
c.2763G>C; p.L921F;	urinary_tract; bladder	carcinoma
c.2644G>A; p.D882N;	urinary_tract; bladder	carcinoma
c.3804G>A; p.M1268I; 7:116210711-116210711	large_intestine; colon	carcinoma; adenocarcinoma
c.3562C>T; p.R1188*;	large_intestine; colon	carcinoma; adenocarcinoma
c.1988C>T; p.S663L;	large_intestine; colon	carcinoma; adenocarcinoma
c.3497G>A; p.R1166Q;	large_intestine; colon	carcinoma; adenocarcinoma
c.662A>G; p.E221G; 7:116127036-116127036	large_intestine; colon	carcinoma; adenocarcinoma
c.913A>G; p.K305E;	prostate	carcinoma; adenocarcinoma
c.3802A>G; p.M1268V;	large_intestine; rectum	carcinoma; adenocarcinoma
c.789G>T; p.T263T;	kidney	carcinoma; clear_cell_renal_cell_carcinoma
c.466T>C; p.S156P;	large_intestine; colon	carcinoma; adenocarcinoma
c.3744T>C; p.Y1248Y;	large_intestine; colon	carcinoma; adenocarcinoma
c.3354T>C; p.N1118N;	large_intestine; caecum	carcinoma; adenocarcinoma
c.3744T>C; p.Y1248Y;	large_intestine; rectum	carcinoma; adenocarcinoma
c.3534G>A; p.M1178I;	large_intestine; colon	carcinoma; adenocarcinoma
c.3737A>G; p.D1246G;	large_intestine; colon	carcinoma; adenocarcinoma
c.663A>G; p.E221E;	large_intestine; caecum	carcinoma; adenocarcinoma
c.3335A>G; p.H1112R; 7:116204700-116204700	large_intestine; caecum	carcinoma; adenocarcinoma
c.3336T>C; p.H1112H;	large_intestine; colon	carcinoma; adenocarcinoma
c.3411A>G; p.G1137G;	large_intestine; colon	carcinoma; adenocarcinoma
c.796A>G; p.R266G;	large_intestine; caecum	carcinoma; adenocarcinoma
c.3371A>G; p.H1124R;	large_intestine; colon	carcinoma; adenocarcinoma
c.3638T>C; p.L1213P;	large_intestine; colon	carcinoma; adenocarcinoma
c.3869T>C; p.L1290P;	large_intestine; caecum	carcinoma; adenocarcinoma
c.3263T>A; p.V1088E;	kidney	carcinoma; clear_cell_renal_cell_carcinoma
c.2871C>G; p.V957V;	kidney	carcinoma; clear_cell_renal_cell_carcinoma
c.504G>T; p.E168D; 7:116126878-116126878	endometrium	carcinoma; endometrioid_carcinoma
c.1024C>A; p.L342I;	endometrium	carcinoma; endometrioid_carcinoma
c.666G>A; p.T222T;	endometrium	carcinoma; endometrioid_carcinoma
c.3805G>A; p.A1269T;	endometrium	carcinoma; endometrioid_carcinoma
c.798G>A; p.R266R;	large_intestine; colon	carcinoma; adenocarcinoma
c.3336T>C; p.H1112H;	large_intestine; colon	carcinoma; adenocarcinoma
c.1127A>G; p.K376R;	large_intestine; colon	carcinoma; adenocarcinoma
c.3869T>C; p.L1290P;	large_intestine; colon	carcinoma; adenocarcinoma
c.487T>C; p.S163P;	large_intestine; rectum	carcinoma; adenocarcinoma
c.468G>T; p.S156S;	large_intestine; caecum	carcinoma; adenocarcinoma
c.3534G>A; p.M1178I;	large_intestine; colon	carcinoma; adenocarcinoma
c.1721C>G; p.P574R;	large_intestine; caecum	carcinoma; adenocarcinoma
c.3737A>G; p.D1246G;	large_intestine; colon	carcinoma; adenocarcinoma
c.3778G>T; p.G1260C; 7:116210685-116210685	large_intestine; colon	carcinoma; adenocarcinoma
c.3785A>G; p.K1262R; 7:116210692-116210692	large_intestine; caecum	carcinoma; adenocarcinoma
c.1619G>A; p.W540*;	large_intestine; rectum	carcinoma; adenocarcinoma
c.1510G>C; p.V504L;	kidney	carcinoma; clear_cell_renal_cell_carcinoma
c.1240G>A; p.D414N;	breast	carcinoma
c.3737A>G; p.D1246G;	large_intestine; colon	carcinoma; adenocarcinoma
c.662A>G; p.E221G; 7:116127036-116127036	large_intestine; colon	carcinoma; adenocarcinoma
c.3738C>T; p.D1246D;	large_intestine; colon	carcinoma; adenocarcinoma
c.4193A>G; p.D1398G;	large_intestine; rectum	carcinoma; adenocarcinoma
c.3353A>T; p.N1118I;	large_intestine; rectum	carcinoma; adenocarcinoma
c.3334C>T; p.H1112Y; 7:116204699-116204699	large_intestine; colon	carcinoma; adenocarcinoma
c.3661A>G; p.R1221G;	large_intestine; colon	carcinoma; adenocarcinoma
c.714A>G; p.L238L;	large_intestine; colon	carcinoma; adenocarcinoma
c.3532A>G; p.M1178V;	large_intestine; caecum	carcinoma; adenocarcinoma
c.796A>G; p.R266G;	large_intestine; caecum	carcinoma; adenocarcinoma
c.3371A>G; p.H1124R;	large_intestine; caecum	carcinoma; adenocarcinoma
c.2381T>A; p.V794D;	large_intestine; caecum	carcinoma; adenocarcinoma
c.3370C>T; p.H1124Y;	large_intestine; rectum	carcinoma; adenocarcinoma
c.2119C>G; p.L707V;	urinary_tract; bladder	carcinoma
c.2135C>G; p.P712R;	urinary_tract; bladder	carcinoma
c.2116A>G; p.I706V;	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia
c.1124A>G; p.N375S; 7:116127498-116127498	kidney	carcinoma
c.3626C>G; p.A1209G; 7:116209327-116209327	kidney	carcinoma
c.3868G>C; p.V1290L; 7:116222960-116222960	kidney	carcinoma
c.1421C>T; p.T474I;	prostate	carcinoma
c.1573T>A; p.S525T;	prostate	carcinoma
c.1128G>A; p.K376K; 7:116127502-116127502	stomach	adenocarcinoma
c.143C>T; p.A48V;	stomach	adenocarcinoma

PCGP germline mutation [Top]

PCGP somatic mutation [Top]

COSMIC somatic mutation [Top]