| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 4233 |
Name | MET |
Synonymous | AUTS9|HGFR|RCCP2|c-Met;met proto-oncogene (hepatocyte growth factor receptor);MET;met proto-oncogene (hepatocyte growth factor receptor) |
Definition | HGF receptor|HGF/SF receptor|SF receptor|hepatocyte growth factor receptor|met proto-oncogene tyrosine kinase|oncogene MET|proto-oncogene c-Met|scatter factor receptor|tyrosine-protein kinase Met |
Position | 7q31 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
ARHGAP35 | REACTOME; |
in same component |
CRKL | NCI_NATURE; |
in same component |
CRK | NCI_NATURE; |
in same component |
CTNNB1 | NCI_NATURE; |
in same component |
EPS15 | NCI_NATURE; |
in same component |
GAB1 | NCI_NATURE; |
in same component |
GAB2 | NCI_NATURE; |
in same component |
HGF | NCI_NATURE; |
in same component |
INPP5D | NCI_NATURE; |
in same component |
INPPL1 | NCI_NATURE; |
in same component |
MUC20 | NCI_NATURE; |
in same component |
PAK4 | NCI_NATURE; |
in same component |
PTPN11 | NCI_NATURE; |
in same component |
RAC1 | REACTOME; |
in same component |
RANBP10 | NCI_NATURE; |
in same component |
RANBP9 | NCI_NATURE; |
in same component |
RND1 | REACTOME; |
in same component |
SDC1 | NCI_NATURE; |
in same component |
SEMA4D | REACTOME; |
in same component |
SOS1 | NCI_NATURE; |
in same component |
WASL | NCI_NATURE; |
interacts with |
BAG1 | HPRD; |
interacts with |
CASP3 | HPRD; |
interacts with |
CBL | BIOGRID; |
interacts with |
CBL | HPRD; |
interacts with |
CBL | MINT; |
interacts with |
CDH1 | BIOGRID; |
interacts with |
CNR1 | HPRD; |
interacts with |
CTNNB1 | BIOGRID; |
interacts with |
CTNNB1 | HPRD; |
interacts with |
CTTN | HPRD; |
interacts with |
DAPK3 | HPRD; |
interacts with |
DNAJA3 | HPRD; |
interacts with |
EGFR | HPRD; |
interacts with |
GAB1 | BIOGRID; |
interacts with |
GAB1 | HPRD; |
interacts with |
Gab1 | MINT; |
interacts with |
GAB1 | MINT; |
interacts with |
GAB2 | BIOGRID; |
interacts with |
GLMN | BIOGRID; |
interacts with |
GLMN | HPRD; |
interacts with |
HGF | BIOGRID; |
interacts with |
HGF | HPRD; |
interacts with |
HGS | HPRD; |
interacts with |
INPP5D | HPRD; |
interacts with |
INPPL1 | HPRD; |
interacts with |
ITGB4 | CELL_MAP; |
interacts with |
ITGB4 | HPRD; |
interacts with |
LRIG1 | BIOGRID; |
interacts with |
MUC20 | HPRD; |
interacts with |
PCBD2 | HPRD; |
interacts with |
PIK3R1 | HPRD; |
interacts with |
PLAU | NCI_NATURE; |
interacts with |
PLAUR | NCI_NATURE; |
interacts with |
PLXNB1 | HPRD; |
interacts with |
PLXNB1 | MINT; |
interacts with |
PTPN11 | HPRD; |
interacts with |
PTPN11 | MINT; |
interacts with |
PTPN1 | MINT; |
interacts with |
PTPRB | HPRD; |
interacts with |
RANBP10 | BIOGRID; |
interacts with |
RANBP10 | HPRD; |
interacts with |
RANBP9 | BIOGRID; |
interacts with |
RANBP9 | HPRD; |
interacts with |
SH3KBP1 | BIOGRID; |
interacts with |
SHC1 | BIOGRID; |
interacts with |
SHC1 | HPRD; |
interacts with |
SMC1A | HPRD; |
interacts with |
SNAPIN | HPRD; |
interacts with |
SNX2 | HPRD; |
interacts with |
SOS1 | BIOGRID; |
interacts with |
SPSB1 | HPRD; |
interacts with |
SRC | BIOGRID; |
interacts with |
SRC | HPRD; |
interacts with |
STAT3 | BIOGRID; |
interacts with |
STAT3 | HPRD; |
interacts with |
VAV1 | HPRD; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
PAX3 | NCI_NATURE; |
metabolic catalysis |
RB1 | NCI_NATURE; |
metabolic catalysis |
TP53 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
ARHGAP35 | REACTOME; |
reacts with |
CDH1 | NCI_NATURE; |
reacts with |
CRKL | NCI_NATURE; |
reacts with |
CRK | NCI_NATURE; |
reacts with |
CTNNA1 | NCI_NATURE; |
reacts with |
CTNNB1 | NCI_NATURE; |
reacts with |
EPS15 | NCI_NATURE; |
reacts with |
GAB1 | NCI_NATURE; |
reacts with |
GAB2 | NCI_NATURE; |
reacts with |
HGF | NCI_NATURE; |
reacts with |
INPP5D | NCI_NATURE; |
reacts with |
INPPL1 | NCI_NATURE; |
reacts with |
ITGA6 | NCI_NATURE; |
reacts with |
ITGB4 | NCI_NATURE; |
reacts with |
MET | NCI_NATURE; |
reacts with |
MET | REACTOME; |
reacts with |
PAK4 | NCI_NATURE; |
reacts with |
PTPN11 | NCI_NATURE; |
reacts with |
RAC1 | REACTOME; |
reacts with |
RANBP10 | NCI_NATURE; |
reacts with |
RANBP9 | NCI_NATURE; |
reacts with |
RND1 | REACTOME; |
reacts with |
SDC1 | NCI_NATURE; |
reacts with |
SEMA4D | REACTOME; |
reacts with |
SOS1 | NCI_NATURE; |
reacts with |
WASL | NCI_NATURE; |
state change |
CBL | NCI_NATURE; |
state change |
CDH1 | NCI_NATURE; |
state change |
CTNNA1 | NCI_NATURE; |
state change |
CTNNB1 | NCI_NATURE; |
state change |
CTNND1 | NCI_NATURE; |
state change |
GAB1 | NCI_NATURE; |
state change |
HGF | NCI_NATURE; |
state change |
HGS | NCI_NATURE; |
state change |
KPNB1 | NCI_NATURE; |
state change |
MET | NCI_NATURE; |
state change |
MET | REACTOME; |
state change |
MUC20 | NCI_NATURE; |
state change |
PTPN11 | NCI_NATURE; |
state change |
PTPN1 | NCI_NATURE; |
state change |
PTPRJ | NCI_NATURE; |
state change |
RAB5A | NCI_NATURE; |
state change |
SH3GL2 | NCI_NATURE; |
state change |
SH3KBP1 | NCI_NATURE; |
state change |
SRC | NCI_NATURE; |