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Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

836

Name

CASP3

Synonymous

CPP32|CPP32B|SCA-1;caspase 3, apoptosis-related cysteine peptidase;CASP3;caspase 3, apoptosis-related cysteine peptidase

Definition

CASP-3|CPP-32|PARP cleavage protease|SREBP cleavage activity 1|Yama|apopain|caspase 3, apoptosis-related cysteine protease|caspase-3|cysteine protease CPP32|procaspase3|protein Yama

Position

4q34

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 BIRC2IMID;

in same component

 BIRC3IMID;

in same component

 BIRC5IMID;

in same component

 DIABLOREACTOME;

in same component

 NAIPIMID;

in same component

 XIAPIMID;

in same component

 XIAPREACTOME;

interacts with

 ADD1HPRD;

interacts with

 AKT1HPRD;

interacts with

 AKT1MINT;

interacts with

 AKT2MINT;

interacts with

 AKT3MINT;

interacts with

 APAF1HPRD;

interacts with

 APAF1INTACT;

interacts with

 APAF1MINT;

interacts with

 ARHPRD;

interacts with

 ARHGDIBHPRD;

interacts with

 BAXNCI_NATURE;

interacts with

 BCAP31HPRD;

interacts with

 BCL2BIOGRID;

interacts with

 BCL2HPRD;

interacts with

 BIDBIOGRID;

interacts with

 BIRC2BIOGRID;

interacts with

 BIRC2HPRD;

interacts with

 BIRC3BIOGRID;

interacts with

 BIRC3HPRD;

interacts with

 BIRC5BIOGRID;

interacts with

 BIRC5HPRD;

interacts with

 BIRC6HPRD;

interacts with

 BIRC7BIOGRID;

interacts with

 BIRC7HPRD;

interacts with

 BLMBIOGRID;

interacts with

 BLMHPRD;

interacts with

 BMXBIOGRID;

interacts with

 BMXHPRD;

interacts with

 BTRCBIOGRID;

interacts with

 CADHPRD;

interacts with

 CASP10BIOGRID;

interacts with

 CASP10HPRD;

interacts with

 CASP1HPRD;

interacts with

 CASP2BIOGRID;

interacts with

 CASP4HPRD;

interacts with

 CASP6BIOGRID;

interacts with

 CASP6HPRD;

interacts with

 CASP8BIOGRID;

interacts with

 CASP8HPRD;

interacts with

 CASP9HPRD;

interacts with

 CASP9INTACT;

interacts with

 CASP9MINT;

interacts with

 CASTHPRD;

interacts with

 CDC27HPRD;

interacts with

 CDC42HPRD;

interacts with

 CDH1HPRD;

interacts with

 CDK11AHPRD;

interacts with

 CDK11BHPRD;

interacts with

 CDKN1AHPRD;

interacts with

 CFLARBIOGRID;

interacts with

 CFLARCELL_MAP;

interacts with

 CFLARHPRD;

interacts with

 CTNNB1HPRD;

interacts with

 CTTNBIOGRID;

interacts with

 DBNLBIOGRID;

interacts with

 DCCBIOGRID;

interacts with

 DCCHPRD;

interacts with

 DCTN1HPRD;

interacts with

 DEDDHPRD;

interacts with

 DSG3HPRD;

interacts with

 EIF2AK2HPRD;

interacts with

 EIF2S1HPRD;

interacts with

 EIF3JHPRD;

interacts with

 EIF4BHPRD;

interacts with

 EIF4G2HPRD;

interacts with

 FBXW11BIOGRID;

interacts with

 FYNHPRD;

interacts with

 GATA1HPRD;

interacts with

 GMNNBIOGRID;

interacts with

 GOLGA3HPRD;

interacts with

 GORASP1BIOGRID;

interacts with

 GORASP1HPRD;

interacts with

 GRIPAP1BIOGRID;

interacts with

 GRIPAP1HPRD;

interacts with

 HCLS1BIOGRID;

interacts with

 HCLS1HPRD;

interacts with

 HEY2BIOGRID;

interacts with

 HIP1HPRD;

interacts with

 HMGB1HPRD;

interacts with

 HNRNPUHPRD;

interacts with

 HSPD1BIOGRID;

interacts with

 HSPD1HPRD;

interacts with

 HSPE1BIOGRID;

interacts with

 HSPE1HPRD;

interacts with

 HTTHPRD;

interacts with

 IL16HPRD;

interacts with

 IL18HPRD;

interacts with

 KCNIP3HPRD;

interacts with

 KRT18HPRD;

interacts with

 LMNB1HPRD;

interacts with

 LYNHPRD;

interacts with

 MAP3K14BIOGRID;

interacts with

 MAP4K1HPRD;

interacts with

 MAPK8IP3HPRD;

interacts with

 MAPTHPRD;

interacts with

 MCL1BIOGRID;

interacts with

 MCL1HPRD;

interacts with

 MDM2HPRD;

interacts with

 MDM4HPRD;

interacts with

 MEF2AHPRD;

interacts with

 METHPRD;

interacts with

 MLH1HPRD;

interacts with

 MYL3HPRD;

interacts with

 NDUFS1BIOGRID;

interacts with

 NEDD4HPRD;

interacts with

 NFE2L2HPRD;

interacts with

 NMT2HPRD;

interacts with

 NMT2MINT;

interacts with

 NUCB2MINT;

interacts with

 PAK2HPRD;

interacts with

 PARGBIOGRID;

interacts with

 PARGHPRD;

interacts with

 PDE10AHPRD;

interacts with

 PDE5AHPRD;

interacts with

 PICALMHPRD;

interacts with

 PIP5K1AHPRD;

interacts with

 PKN1HPRD;

interacts with

 PKN2HPRD;

interacts with

 PLA2G4AHPRD;

interacts with

 PPP3CAHPRD;

interacts with

 PRKCQHPRD;

interacts with

 PRKCZHPRD;

interacts with

 PRKDCHPRD;

interacts with

 PSEN1HPRD;

interacts with

 PSEN2HPRD;

interacts with

 PSIP1HPRD;

interacts with

 PSME3HPRD;

interacts with

 PTBP1HPRD;

interacts with

 PXNHPRD;

interacts with

 RABEP1HPRD;

interacts with

 RAC1HPRD;

interacts with

 RAD51HPRD;

interacts with

 RASA1HPRD;

interacts with

 RB1HPRD;

interacts with

 RBX1BIOGRID;

interacts with

 RFC1HPRD;

interacts with

 RNF2BIOGRID;

interacts with

 ROCK1HPRD;

interacts with

 SARS2HPRD;

interacts with

 SLKHPRD;

interacts with

 SP1HPRD;

interacts with

 SPTAN1HPRD;

interacts with

 SREBF2BIOGRID;

interacts with

 SREBF2HPRD;

interacts with

 SRFHPRD;

interacts with

 SRP72HPRD;

interacts with

 STK24HPRD;

interacts with

 STK3HPRD;

interacts with

 STK4HPRD;

interacts with

 TFAP2AHPRD;

interacts with

 TGM2HPRD;

interacts with

 THAP11HPRD;

interacts with

 TOP1HPRD;

interacts with

 TRAF1HPRD;

interacts with

 TRAF3BIOGRID;

interacts with

 TRAF3HPRD;

interacts with

 UBE4BHPRD;

interacts with

 USO1BIOGRID;

interacts with

 USO1HPRD;

interacts with

 VAV1HPRD;

interacts with

 VIMHPRD;

interacts with

 WEE1HPRD;

interacts with

 XIAPBIOGRID;

interacts with

 XIAPHPRD;

interacts with

 XIAPMINT;

interacts with

 YWHAEHPRD;

interacts with

 YWHAEMINT;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 NFATC2NCI_NATURE;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 BIRC2IMID;

reacts with

 BIRC3IMID;

reacts with

 BIRC5IMID;

reacts with

 CASP3IMID;

reacts with

 CASP3NCI_NATURE;

reacts with

 CASP3REACTOME;

reacts with

 DIABLOREACTOME;

reacts with

 NAIPIMID;

reacts with

 XIAPIMID;

reacts with

 XIAPREACTOME;

state change

 APAF1NCI_NATURE;

state change

 APPL1REACTOME;

state change

 BADNCI_NATURE;

state change

 BCL2L11NCI_NATURE;

state change

 BIRC3NCI_NATURE;

state change

 CASP10NCI_NATURE;

state change

 CASP1NCI_NATURE;

state change

 CASP2NCI_NATURE;

state change

 CASP8IMID;

state change

 CASP8NCI_NATURE;

state change

 CASP9IMID;

state change

 CASP9NCI_NATURE;

state change

 CASP9REACTOME;

state change

 DCCREACTOME;

state change

 FADDNCI_NATURE;

state change

 GZMBNCI_NATURE;

state change

 LPAR1NCI_NATURE;

state change

 LPAR3NCI_NATURE;

state change

 PRKCDNCI_NATURE;

state change

 SDC2NCI_NATURE;

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