Pediatric cancer gene database (Pedican) Home
Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7153

Name

TOP2A

Synonymous

TOP2|TP2A;topoisomerase (DNA) II alpha 170kDa;TOP2A;topoisomerase (DNA) II alpha 170kDa

Definition

DNA gyrase|DNA topoisomerase (ATP-hydrolyzing)|DNA topoisomerase 2-alpha|DNA topoisomerase II, 170 kD|DNA topoisomerase II, alpha isozyme

Position

17q21-q22

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

interacts with

 AIREBIOGRID;

interacts with

 BRCA1BIOGRID;

interacts with

 CDC5LBIOGRID;

interacts with

 CDT1BIOGRID;

interacts with

 CSNK2A1HPRD;

interacts with

 CTCFHPRD;

interacts with

 DDX17HPRD;

interacts with

 DDX23HPRD;

interacts with

 DDX50HPRD;

interacts with

 DDX5HPRD;

interacts with

 DFFBBIOGRID;

interacts with

 DFFBHPRD;

interacts with

 DHX9BIOGRID;

interacts with

 DHX9HPRD;

interacts with

 EFTUD2HPRD;

interacts with

 ELAVL1HPRD;

interacts with

 FBLHPRD;

interacts with

 H1FXHPRD;

interacts with

 HDAC1BIOGRID;

interacts with

 HDAC2BIOGRID;

interacts with

 HDAC2HPRD;

interacts with

 HNRNPA1HPRD;

interacts with

 HNRNPA2B1HPRD;

interacts with

 HNRNPA3HPRD;

interacts with

 HNRNPCHPRD;

interacts with

 HNRNPLHPRD;

interacts with

 HNRNPRHPRD;

interacts with

 HNRNPUHPRD;

interacts with

 JUNBIOGRID;

interacts with

 JUNHPRD;

interacts with

 KPNA1HPRD;

interacts with

 KPNA3HPRD;

interacts with

 LMNAHPRD;

interacts with

 MAPK1BIOGRID;

interacts with

 MKI67HPRD;

interacts with

 NOLC1HPRD;

interacts with

 NONOHPRD;

interacts with

 NOP2HPRD;

interacts with

 NR4A1BIOGRID;

interacts with

 PARP1HPRD;

interacts with

 PIAS1HPRD;

interacts with

 PIN1BIOGRID;

interacts with

 PIN1HPRD;

interacts with

 PRKCAHPRD;

interacts with

 PRKCBHPRD;

interacts with

 PRKCGHPRD;

interacts with

 PRKDCHPRD;

interacts with

 PRPF8HPRD;

interacts with

 RB1HPRD;

interacts with

 SETMARBIOGRID;

interacts with

 SETHPRD;

interacts with

 SF3B1HPRD;

interacts with

 SF3B3HPRD;

interacts with

 SFPQHPRD;

interacts with

 SNRNP200HPRD;

interacts with

 SNRPA1HPRD;

interacts with

 SRPK1HPRD;

interacts with

 SRSF1HPRD;

interacts with

 SSRP1HPRD;

interacts with

 SUMO4HPRD;

interacts with

 TCOF1HPRD;

interacts with

 TOP1HPRD;

interacts with

 TOP2BBIOGRID;

interacts with

 TOP2BHPRD;

interacts with

 TP53BIOGRID;

interacts with

 XPO1HPRD;

interacts with

 XRCC5BIOGRID;

interacts with

 YWHAEBIOGRID;

interacts with

 YWHAEHPRD;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 LIN37REACTOME;

metabolic catalysis

 LIN52REACTOME;

metabolic catalysis

 LIN54REACTOME;

metabolic catalysis

 LIN9REACTOME;

metabolic catalysis

 RBBP4REACTOME;

metabolic catalysis

 RBL2REACTOME;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 CDC25AREACTOME;

reacts with

 CDC6REACTOME;

reacts with

 E2F1REACTOME;

reacts with

 PCNAREACTOME;

reacts with

 RBL1REACTOME;

')