Entrez Gene

Pediatric cancer gene database (Pedican) Home

General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information
Gene ID	7099
Name	TLR4
Synonymous	ARMD10\|CD284\|TOLL\|hToll;toll-like receptor 4;TLR4;toll-like receptor 4
Definition	homolog of Drosophila toll
Position	9q33.1
Gene Type	protein-coding
Gene Interactions:	Physical Interaction Metabolic Interaction Signaling Interaction

Interaction Type	Interactor	Data Source
Physical Interaction [Top]
in same component	BGN	NCI_NATURE;
in same component	CHUK	REACTOME;
in same component	HMGB1	NCI_NATURE;
in same component	HSPD1	NCI_NATURE;
in same component	IKBKB	REACTOME;
in same component	IKBKG	REACTOME;
in same component	IRAK1	NCI_NATURE;
in same component	IRAK2	NCI_NATURE;
in same component	IRAK4	NCI_NATURE;
in same component	LY96	NCI_NATURE;
in same component	LY96	REACTOME;
in same component	MAP3K7	REACTOME;
in same component	MYD88	NCI_NATURE;
in same component	RIPK1	REACTOME;
in same component	S100A8	NCI_NATURE;
in same component	S100A9	NCI_NATURE;
in same component	TAB1	REACTOME;
in same component	TICAM1	REACTOME;
in same component	TICAM2	REACTOME;
in same component	TIRAP	NCI_NATURE;
in same component	TRAF6	REACTOME;
interacts with	EGFR	MINT;
interacts with	F2RL1	INTACT;
interacts with	LY96	BIOGRID;
interacts with	MYD88	BIOGRID;
interacts with	MYD88	MINT;
interacts with	PPP4C	BIOGRID;
interacts with	RNF216	BIOGRID;
interacts with	SIGIRR	BIOGRID;
interacts with	TICAM2	BIOGRID;
interacts with	TIRAP	BIOGRID;
interacts with	TLR1	BIOGRID;
interacts with	TOLLIP	BIOGRID;

Metabolic Interaction [Top]
	There is no record for TLR4

Interaction Type	Interactor	Data Source
Signaling Interaction [Top]
reacts with	BGN	NCI_NATURE;
reacts with	CHUK	REACTOME;
reacts with	HMGB1	NCI_NATURE;
reacts with	HSPD1	NCI_NATURE;
reacts with	IKBKB	REACTOME;
reacts with	IKBKG	REACTOME;
reacts with	IRAK1	NCI_NATURE;
reacts with	IRAK2	NCI_NATURE;
reacts with	IRAK4	NCI_NATURE;
reacts with	LY96	NCI_NATURE;
reacts with	LY96	REACTOME;
reacts with	MAP3K7	REACTOME;
reacts with	MYD88	NCI_NATURE;
reacts with	RIPK1	REACTOME;
reacts with	S100A8	NCI_NATURE;
reacts with	S100A9	NCI_NATURE;
reacts with	TAB1	REACTOME;
reacts with	TICAM1	REACTOME;
reacts with	TICAM2	REACTOME;
reacts with	TIRAP	NCI_NATURE;
reacts with	TLR4	NCI_NATURE;
reacts with	TLR4	REACTOME;
reacts with	TRAF6	REACTOME;
state change	CD14	NCI_NATURE;
state change	CD180	REACTOME;
state change	LY86	REACTOME;
state change	LY96	REACTOME;
state change	MAP3K7	REACTOME;
state change	TAB1	REACTOME;
state change	TICAM1	REACTOME;
state change	TICAM2	REACTOME;
state change	TLR4	REACTOME;
state change	TRAF6	REACTOME;

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