Entrez Gene

Pediatric cancer gene database (Pedican) Home

General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information
Gene ID	3562
Name	IL3
Synonymous	IL-3\|MCGF\|MULTI-CSF;interleukin 3 (colony-stimulating factor, multiple);IL3;interleukin 3 (colony-stimulating factor, multiple)
Definition	P-cell stimulating factor\|P-cell-stimulating factor\|hematopoietic growth factor\|interleukin-3\|mast cell growth factor\|mast-cell growth factor\|multilineage-colony-stimulating factor\|multipotential colony-stimulating factor
Position	5q31.1
Gene Type	protein-coding
Gene Interactions:	Physical Interaction Metabolic Interaction Signaling Interaction

Interaction Type	Interactor	Data Source
Physical Interaction [Top]
in same component	CSF2RB	NCI_NATURE;
in same component	CSF2RB	REACTOME;
in same component	GAB2	NCI_NATURE;
in same component	IL3RA	NCI_NATURE;
in same component	IL3RA	REACTOME;
in same component	INPP5D	NCI_NATURE;
in same component	JAK2	NCI_NATURE;
in same component	JAK2	REACTOME;
in same component	PIK3CA	NCI_NATURE;
in same component	PIK3R1	NCI_NATURE;
in same component	PTPN11	NCI_NATURE;
in same component	SHC1	NCI_NATURE;
in same component	YWHAZ	NCI_NATURE;
interacts with	CSF2RB	BIOGRID;
interacts with	CSF2RB	HPRD;
interacts with	HRAS	HPRD;
interacts with	IL3RA	BIOGRID;
interacts with	IL3RA	HPRD;
interacts with	PIK3CA	HPRD;

Interaction Type	Interactor	Data Source
Metabolic Interaction [Top]
metabolic catalysis	FOS	NCI_NATURE;
metabolic catalysis	JUN	NCI_NATURE;
metabolic catalysis	POU2F1	NCI_NATURE;

Interaction Type	Interactor	Data Source
Signaling Interaction [Top]
reacts with	CSF2RB	NCI_NATURE;
reacts with	CSF2RB	REACTOME;
reacts with	GAB2	NCI_NATURE;
reacts with	IL3	NCI_NATURE;
reacts with	IL3	REACTOME;
reacts with	IL3RA	NCI_NATURE;
reacts with	IL3RA	REACTOME;
reacts with	INPP5D	NCI_NATURE;
reacts with	JAK2	NCI_NATURE;
reacts with	JAK2	REACTOME;
reacts with	PIK3CA	NCI_NATURE;
reacts with	PIK3R1	NCI_NATURE;
reacts with	PTPN11	NCI_NATURE;
reacts with	SHC1	NCI_NATURE;
reacts with	YWHAZ	NCI_NATURE;

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