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Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

356

Name

FASLG

Synonymous

APT1LG1|CD178|CD95-L|CD95L|FASL|TNFSF6;Fas ligand (TNF superfamily, member 6);FASLG;Fas ligand (TNF superfamily, member 6)

Definition

APTL|CD95 ligand|apoptosis (APO-1) antigen ligand 1|apoptosis antigen ligand|fas antigen ligand|tumor necrosis factor (ligand) superfamily, member 6|tumor necrosis factor ligand superfamily member 6

Position

1q23

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 BTKNCI_NATURE;

in same component

 CASP10NCI_NATURE;

in same component

 CASP10REACTOME;

in same component

 CASP8NCI_NATURE;

in same component

 CASP8REACTOME;

in same component

 CFLARNCI_NATURE;

in same component

 DAXXNCI_NATURE;

in same component

 FADDNCI_NATURE;

in same component

 FADDREACTOME;

in same component

 FASIMID;

in same component

 FASNCI_NATURE;

in same component

 FASREACTOME;

in same component

 MAP3K5NCI_NATURE;

in same component

 RIPK1NCI_NATURE;

in same component

 SRCNCI_NATURE;

in same component

 SYKNCI_NATURE;

interacts with

 Ap2b1MINT;

interacts with

 APBB1HPRD;

interacts with

 ARHGAP4MINT;

interacts with

 ARHGDIABIOGRID;

interacts with

 BIDBIOGRID;

interacts with

 CASP10BIOGRID;

interacts with

 CASP10MINT;

interacts with

 CASP8BIOGRID;

interacts with

 CASP8MINT;

interacts with

 DAXXHPRD;

interacts with

 EZRBIOGRID;

interacts with

 EZRHPRD;

interacts with

 FADDBIOGRID;

interacts with

 FADDHPRD;

interacts with

 FADDMINT;

interacts with

 FASBIOGRID;

interacts with

 FGRBIOGRID;

interacts with

 FN1BIOGRID;

interacts with

 FNBP1BIOGRID;

interacts with

 FNBP1HPRD;

interacts with

 FNBP1MINT;

interacts with

 FYNBIOGRID;

interacts with

 FYNHPRD;

interacts with

 GRAP2BIOGRID;

interacts with

 GRAP2HPRD;

interacts with

 GRAPBIOGRID;

interacts with

 GRAPHPRD;

interacts with

 LCKBIOGRID;

interacts with

 LCKHPRD;

interacts with

 LYNBIOGRID;

interacts with

 MAPK8BIOGRID;

interacts with

 MLLHPRD;

interacts with

 MMP7BIOGRID;

interacts with

 MMP7HPRD;

interacts with

 MSNBIOGRID;

interacts with

 NCF1HPRD;

interacts with

 NCK1BIOGRID;

interacts with

 NCK1HPRD;

interacts with

 PACSIN1MINT;

interacts with

 PACSIN2BIOGRID;

interacts with

 PACSIN2HPRD;

interacts with

 Pacsin2MINT;

interacts with

 PACSIN2MINT;

interacts with

 Pacsin3MINT;

interacts with

 PACSIN3MINT;

interacts with

 PDCD6HPRD;

interacts with

 PIK3R1HPRD;

interacts with

 PIN1HPRD;

interacts with

 PRPF40AHPRD;

interacts with

 PSTPIP1HPRD;

interacts with

 PSTPIP1MINT;

interacts with

 PTPN12HPRD;

interacts with

 PTPN13BIOGRID;

interacts with

 PTPN13HPRD;

interacts with

 RHOABIOGRID;

interacts with

 Snx18MINT;

interacts with

 SRCHPRD;

interacts with

 SRGAP2MINT;

interacts with

 TNFRSF10BBIOGRID;

interacts with

 TNFRSF1ABIOGRID;

interacts with

 TNFRSF6BBIOGRID;

interacts with

 TNFRSF6BHPRD;

interacts with

 TRIP10MINT;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 CD247NCI_NATURE;

metabolic catalysis

 EGR2NCI_NATURE;

metabolic catalysis

 EGR3NCI_NATURE;

metabolic catalysis

 FOSNCI_NATURE;

metabolic catalysis

 FOXO3NCI_NATURE;

metabolic catalysis

 IL12ANCI_NATURE;

metabolic catalysis

 IL12BNCI_NATURE;

metabolic catalysis

 IL12RB1NCI_NATURE;

metabolic catalysis

 IL12RB2NCI_NATURE;

metabolic catalysis

 JAK2NCI_NATURE;

metabolic catalysis

 JUNNCI_NATURE;

metabolic catalysis

 NFATC2NCI_NATURE;

metabolic catalysis

 PRKCENCI_NATURE;

metabolic catalysis

 PRKCQNCI_NATURE;

metabolic catalysis

 SIRT1NCI_NATURE;

metabolic catalysis

 TYK2NCI_NATURE;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 BTKNCI_NATURE;

reacts with

 CASP10NCI_NATURE;

reacts with

 CASP10REACTOME;

reacts with

 CASP8NCI_NATURE;

reacts with

 CASP8REACTOME;

reacts with

 CFLARNCI_NATURE;

reacts with

 DAXXNCI_NATURE;

reacts with

 FADDNCI_NATURE;

reacts with

 FADDREACTOME;

reacts with

 FASIMID;

reacts with

 FASNCI_NATURE;

reacts with

 FASREACTOME;

reacts with

 FASLGIMID;

reacts with

 FASLGNCI_NATURE;

reacts with

 FASLGREACTOME;

reacts with

 MAP3K5NCI_NATURE;

reacts with

 RIPK1NCI_NATURE;

reacts with

 SRCNCI_NATURE;

reacts with

 SYKNCI_NATURE;

state change

 CASP8NCI_NATURE;

state change

 CFLARNCI_NATURE;

state change

 CLTCNCI_NATURE;

state change

 EZRNCI_NATURE;

state change

 FADDNCI_NATURE;

state change

 FASNCI_NATURE;

state change

 FASLGNCI_NATURE;

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