| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 1493 |
Name | CTLA4 |
Synonymous | CD|CD152|CELIAC3|CTLA-4|GRD4|GSE|ICOS|IDDM12;cytotoxic T-lymphocyte-associated protein 4;CTLA4;cytotoxic T-lymphocyte-associated protein 4 |
Definition | CD152 isoform|celiac disease 3|cytotoxic T lymphocyte associated antigen 4 short spliced form|cytotoxic T-lymphocyte antigen 4|cytotoxic T-lymphocyte protein 4|cytotoxic T-lymphocyte-associated antigen 4|cytotoxic T-lymphocyte-associated serine esterase-4 |
Position | 2q33 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
PTPN11 | REACTOME; |
interacts with |
AP1M1 | BIOGRID; |
interacts with |
AP1M1 | HPRD; |
interacts with |
AP2M1 | BIOGRID; |
interacts with |
AP2M1 | HPRD; |
interacts with |
CD80 | BIOGRID; |
interacts with |
CD86 | BIOGRID; |
interacts with |
CD86 | HPRD; |
interacts with |
FYN | BIOGRID; |
interacts with |
FYN | HPRD; |
interacts with |
JAK2 | BIOGRID; |
interacts with |
JAK2 | HPRD; |
interacts with |
LCK | BIOGRID; |
interacts with |
LCK | HPRD; |
interacts with |
LYN | BIOGRID; |
interacts with |
LYN | HPRD; |
interacts with |
PIK3R1 | HPRD; |
interacts with |
PIK3R1 | MINT; |
interacts with |
PPP2R5A | BIOGRID; |
interacts with |
PPP2R5A | HPRD; |
interacts with |
PTPN11 | HPRD; |
interacts with |
STAT5A | HPRD; |
interacts with |
STAT5B | HPRD; |
interacts with |
TXK | HPRD; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
FOXP3 | NCI_NATURE; |
metabolic catalysis |
NFATC2 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
CTLA4 | REACTOME; |
reacts with |
PTPN11 | REACTOME; |