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Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

9063

Name

PIAS2

Synonymous

ARIP3|DIP|MIZ|MIZ1|PIASX|PIASX-ALPHA|PIASX-BETA|SIZ2|ZMIZ4;protein inhibitor of activated STAT, 2;PIAS2;protein inhibitor of activated STAT, 2

Definition

DAB2-interacting protein|E3 SUMO-protein ligase PIAS2|androgen receptor-interacting protein 3|msx-interacting zinc finger protein|protein inhibitor of activated STAT X|zinc finger, MIZ-type containing 4

Position

18q21.1

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

Ubc9(h) + PIAS2(h) <==> Ubc9(h):PIAS2(h) (binding)
PIAS2(h) + Steerin2(h) <==> PIAS2(h):Steerin2(h) (binding)
PIAS2(h) --> PIAS2(h) (expression).
PIAS2-alpha(h) + Fli-1(h) <==> PIAS2-alpha(h):Fli-1(h) (binding)
Sox9(m.s.) + PIAS2-alpha(h) <==> Sox9(m.s.):PIAS2-alpha(h) (binding)
NIN-isoform1(h) + PIAS2-alpha(h) <==> NIN-isoform1(h):PIAS2-alpha(h) (binding)
RFP-alpha(h) + PIAS2-alpha(h) <==> RFP-alpha(h):PIAS2-alpha(h) (binding)
AIRE(m.s.) + PIAS2-alpha(h) <==> AIRE(m.s.):PIAS2-alpha(h) (binding)
p53-isoform1(h) + PIAS2-alpha(h) <==> p53-isoform1(h):PIAS2-alpha(h) (binding)
PIAS2(h) --> PIAS2-alpha(h) (expression).
MR-isoform1(h) + sumo1(h) --Aos1(m.s.):SAE2(m.s.),Ubc9(m.s.),PIAS2-alpha(h)--> MR-isoform1(h){sumo} (sumoylation)
ITF-2(h) + PIAS2-beta(h) <==> ITF-2(h):PIAS2-beta(h) (binding)
Sox9(m.s.) + PIAS2-beta(h) <==> Sox9(m.s.):PIAS2-beta(h) (binding)
MR-isoform1(h) + PIAS2-beta(h) <==> MR-isoform1(h):PIAS2-beta(h) (binding)
PIAS2(h) --> PIAS2-beta(h) (expression).
MR-isoform1(h) + sumo1(h) --Aos1(m.s.):SAE2(m.s.),Ubc9(m.s.),PIAS2-beta(h)--> MR-isoform1(h){sumo} (sumoylation)
PIAS2(h) --> PIAS-NY(h) (expression).

Post Translational Modification   [Top]

There is no record for PIAS2

Methylation Profile   [Top]

Chromosome

Location

Source

chr18

Promoter: 42750964 - 42752964Agilent_014791

chr18

Promoter: 42750964 - 42752964GSE27584

chr18

Promoter: 42750964 - 42752964GSE27584

chr18

Promoter: 42750964 - 42752964Agilent_014791_44K


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