| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 9063 |
Name | PIAS2 |
Synonymous | ARIP3|DIP|MIZ|MIZ1|PIASX|PIASX-ALPHA|PIASX-BETA|SIZ2|ZMIZ4;protein inhibitor of activated STAT, 2;PIAS2;protein inhibitor of activated STAT, 2 |
Definition | DAB2-interacting protein|E3 SUMO-protein ligase PIAS2|androgen receptor-interacting protein 3|msx-interacting zinc finger protein|protein inhibitor of activated STAT X|zinc finger, MIZ-type containing 4 |
Position | 18q21.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | Ubc9(h) + PIAS2(h) <==> Ubc9(h):PIAS2(h) (binding) | PIAS2(h) + Steerin2(h) <==> PIAS2(h):Steerin2(h) (binding) | PIAS2(h) --> PIAS2(h) (expression). | PIAS2-alpha(h) + Fli-1(h) <==> PIAS2-alpha(h):Fli-1(h) (binding) | Sox9(m.s.) + PIAS2-alpha(h) <==> Sox9(m.s.):PIAS2-alpha(h) (binding) | NIN-isoform1(h) + PIAS2-alpha(h) <==> NIN-isoform1(h):PIAS2-alpha(h) (binding) | RFP-alpha(h) + PIAS2-alpha(h) <==> RFP-alpha(h):PIAS2-alpha(h) (binding) | AIRE(m.s.) + PIAS2-alpha(h) <==> AIRE(m.s.):PIAS2-alpha(h) (binding) | p53-isoform1(h) + PIAS2-alpha(h) <==> p53-isoform1(h):PIAS2-alpha(h) (binding) | PIAS2(h) --> PIAS2-alpha(h) (expression). | MR-isoform1(h) + sumo1(h) --Aos1(m.s.):SAE2(m.s.),Ubc9(m.s.),PIAS2-alpha(h)--> MR-isoform1(h){sumo} (sumoylation) | ITF-2(h) + PIAS2-beta(h) <==> ITF-2(h):PIAS2-beta(h) (binding) | Sox9(m.s.) + PIAS2-beta(h) <==> Sox9(m.s.):PIAS2-beta(h) (binding) | MR-isoform1(h) + PIAS2-beta(h) <==> MR-isoform1(h):PIAS2-beta(h) (binding) | PIAS2(h) --> PIAS2-beta(h) (expression). | MR-isoform1(h) + sumo1(h) --Aos1(m.s.):SAE2(m.s.),Ubc9(m.s.),PIAS2-beta(h)--> MR-isoform1(h){sumo} (sumoylation) | PIAS2(h) --> PIAS-NY(h) (expression). |
|---|
Post Translational Modification [Top] | |||
There is no record for PIAS2 | |||
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr18 |
Promoter: 42750964 - 42752964 | Agilent_014791 |
chr18 |
Promoter: 42750964 - 42752964 | GSE27584 |
chr18 |
Promoter: 42750964 - 42752964 | GSE27584 |
chr18 |
Promoter: 42750964 - 42752964 | Agilent_014791_44K |