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Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

9063

Name

PIAS2

Synonymous

ARIP3|DIP|MIZ|MIZ1|PIASX|PIASX-ALPHA|PIASX-BETA|SIZ2|ZMIZ4;protein inhibitor of activated STAT, 2;PIAS2;protein inhibitor of activated STAT, 2

Definition

DAB2-interacting protein|E3 SUMO-protein ligase PIAS2|androgen receptor-interacting protein 3|msx-interacting zinc finger protein|protein inhibitor of activated STAT X|zinc finger, MIZ-type containing 4

Position

18q21.1

Gene Type

protein-coding

Gene Mutation:

PCGP germline mutation
PCGP somatic mutation
COSMIC somatic mutation

PCGP germline mutation   [Top]

There is no record for PIAS2

PCGP somatic mutation   [Top]

There is no record for PIAS2

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

c.277G>A; p.E93K;

breastcarcinoma; HER-positive_carcinoma

c.538A>T; p.I180F;

skin; upper_armmalignant_melanoma

c.997A>G; p.S333G;

large_intestine; coloncarcinoma; adenocarcinoma

c.1628G>A; p.S543N;

large_intestine; coloncarcinoma; adenocarcinoma

c.494G>A; p.S165N;

haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; diffuse_large_B_cell_lymphoma

c.1013C>G; p.T338S;

upper_aerodigestive_tract; pharynxcarcinoma; squamous_cell_carcinoma

c.1664C>T; p.S555F;

skin; head_neckmalignant_melanoma; superficial_spreading

c.1665C>T; p.S555S;

skin; head_neckmalignant_melanoma; superficial_spreading

c.1648+1G>T; p.?;

lungcarcinoma; adenocarcinoma

c.191G>T; p.R64L;

lungcarcinoma; adenocarcinoma

c.1672C>A; p.P558T;

ovarycarcinoma; clear_cell_carcinoma

c.180G>T; p.L60F;

lungcarcinoma; small_cell_carcinoma

c.952C>T; p.H318Y;

lungcarcinoma; adenocarcinoma

c.1361G>T; p.C454F; 18:42662067-42662067

 ovarycarcinoma; serous_carcinoma

c.285C>T; p.D95D;

lungcarcinoma; squamous_cell_carcinoma

c.610G>T; p.D204Y;

ovarycarcinoma; serous_carcinoma

c.1060A>T; p.T354S;

lungcarcinoma; squamous_cell_carcinoma

c.1556C>T; p.S519L;

ovarycarcinoma; serous_carcinoma

c.433G>A; p.D145N;

lungcarcinoma; squamous_cell_carcinoma

c.670G>T; p.D224Y;

lung; right_lower_lobecarcinoma; adenocarcinoma

c.889C>G; p.R297G;

endometriumcarcinoma; endometrioid_carcinoma

c.492G>A; p.T164T;

endometriumcarcinoma; endometrioid_carcinoma

c.1556C>T; p.S519L;

large_intestine; coloncarcinoma; adenocarcinoma

c.1556C>T; p.S519L;

large_intestine; coloncarcinoma; adenocarcinoma

c.1519T>G; p.Y507D;

haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemia

c.1660C>A; p.L554I;

large_intestine; rectumcarcinoma; adenocarcinoma

c.1451C>A; p.P484H;

endometriumcarcinoma; endometrioid_carcinoma

c.1021C>T; p.R341W;

endometriumcarcinoma; endometrioid_carcinoma

c.239C>A; p.S80*;

endometriumcarcinoma; endometrioid_carcinoma

c.1556C>T; p.S519L;

endometriumcarcinoma; endometrioid_carcinoma

c.175G>T; p.E59*;

endometriumcarcinoma; endometrioid_carcinoma

c.586G>A; p.D196N;

endometriumcarcinoma; endometrioid_carcinoma

c.188G>A; p.R63H;

endometriumcarcinoma; endometrioid_carcinoma

c.426C>T; p.V142V;

endometriumcarcinoma; endometrioid_carcinoma

c.794C>A; p.S265Y;

endometriumcarcinoma; endometrioid_carcinoma

c.447A>C; p.K149N;

endometriumcarcinoma; endometrioid_carcinoma

c.1805G>C; p.S602T;

breastcarcinoma

c.242C>T; p.S81L;

endometriumcarcinoma; endometrioid_carcinoma

c.16G>T; p.E6*;

endometriumcarcinoma; endometrioid_carcinoma

c.1360T>C; p.C454R;

large_intestine; coloncarcinoma; adenocarcinoma

c.199C>T; p.R67*;

endometriumcarcinoma; endometrioid_carcinoma

c.98G>A; p.R33H;

endometriumcarcinoma; endometrioid_carcinoma

c.1319C>T; p.P440L;

endometriumcarcinoma; endometrioid_carcinoma

c.1173_1174insA; p.A392fs*4;

breastcarcinoma

c.1281G>A; p.M427I;

breastcarcinoma

c.1613A>G; p.H538R;

breastcarcinoma

c.420T>C; p.P140P;

large_intestine; caecumcarcinoma; adenocarcinoma

c.1399G>A; p.V467I;

skinmalignant_melanoma

c.833C>T; p.S278F;

skinmalignant_melanoma

c.1660C>T; p.L554F;

skin; mucosalmalignant_melanoma

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