| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 7515 |
Name | XRCC1 |
Synonymous | RCC;X-ray repair complementing defective repair in Chinese hamster cells 1;XRCC1;X-ray repair complementing defective repair in Chinese hamster cells 1 |
Definition | DNA repair protein XRCC1|X-ray repair cross-complementing protein 1|X-ray-repair, complementing defective, repair in Chinese hamster |
Position | 19q13.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | XRCC1(h) --> xrcc1(h) (expression). | UDG-isoform2(h) + xrcc1(h) <==> UDG-isoform2(h):xrcc1(h) (binding) | pnkp(h) + xrcc1(h) <==> pnkp(h):xrcc1(h) (binding) | xrcc1(h) + ligase III(h) <==> xrcc1(h):ligase III(h) (binding) | PARP(h) + xrcc1(h) <==> PARP(h):xrcc1(h) (binding) | XRCC1(h) --> xrcc1(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 371 | Phosphoserine (by PRKDC). | Swiss-Prot 53.0 | 408 | Phosphoserine. | Swiss-Prot 53.0 | 409 | Phosphoserine. | Swiss-Prot 53.0 | 410 | Phosphoserine. | Swiss-Prot 53.0 | 416 | Phosphoserine. | Swiss-Prot 53.0 | 418 | Phosphoserine. | Swiss-Prot 53.0 | 421 | Phosphoserine. | Swiss-Prot 53.0 | 447 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 453 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 475 | Phosphoserine (CK2 alpha) | 15066279 | Phospho.ELM 6.0 | 485 | Phosphoserine (CK2 alpha) | 15066279 | Phospho.ELM 6.0 | 488 | Phosphothreonine (CK2 alpha) | 15066279 | Phospho.ELM 6.0 | 518 | Phosphoserine (CK2 alpha) | 15066279 | Phospho.ELM 6.0 | 519 | Phosphothreonine (CK2 alpha) | 15066279 | Phospho.ELM 6.0 | 523 | Phosphothreonine (CK2 alpha) | 15066279 | Phospho.ELM 6.0 | 525 | Phosphoserine (CK2 alpha) | 15066279 | Phospho.ELM 6.0 | 268 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 408 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 409 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 410 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 416 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 418 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 421 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 453 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr19 |
Promoter: 48771055 - 48773055 | Agilent_014791 |
chr19 |
Promoter: 48771055 - 48773055 | GoldenGate_Methylation_Cancer_Panel_I |
chr19 |
Promoter: 48771055 - 48773055 | GSE27584 |
chr19 |
Promoter: 48771055 - 48773055 | Agilent_014791_44K |