| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 7515 |
Name | XRCC1 |
Synonymous | RCC;X-ray repair complementing defective repair in Chinese hamster cells 1;XRCC1;X-ray repair complementing defective repair in Chinese hamster cells 1 |
Definition | DNA repair protein XRCC1|X-ray repair cross-complementing protein 1|X-ray-repair, complementing defective, repair in Chinese hamster |
Position | 19q13.2 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
LIG3 | REACTOME; |
in same component |
POLB | REACTOME; |
interacts with |
APEX1 | BIOGRID; |
interacts with |
APLF | HPRD; |
interacts with |
APLF | MINT; |
interacts with |
APTX | BIOGRID; |
interacts with |
APTX | HPRD; |
interacts with |
APTX | MINT; |
interacts with |
CCNO | MINT; |
interacts with |
CHD1L | BIOGRID; |
interacts with |
CHEK2 | MINT; |
interacts with |
CSNK2A1 | HPRD; |
interacts with |
CSNK2A1 | MINT; |
interacts with |
CSNK2A2 | HPRD; |
interacts with |
FYN | MINT; |
interacts with |
H2AFX | MINT; |
interacts with |
LIG3 | BIOGRID; |
interacts with |
LIG3 | HPRD; |
interacts with |
LIG3 | MINT; |
interacts with |
MPG | MINT; |
interacts with |
NCAPG | BIOGRID; |
interacts with |
NEIL1 | BIOGRID; |
interacts with |
NEIL1 | HPRD; |
interacts with |
OGG1 | BIOGRID; |
interacts with |
OGG1 | HPRD; |
interacts with |
PARP1 | BIOGRID; |
interacts with |
PARP1 | HPRD; |
interacts with |
PARP1 | MINT; |
interacts with |
PARP2 | BIOGRID; |
interacts with |
PARP2 | HPRD; |
interacts with |
PCNA | BIOGRID; |
interacts with |
PCNA | HPRD; |
interacts with |
PNKP | BIOGRID; |
interacts with |
PNKP | HPRD; |
interacts with |
POLB | BIOGRID; |
interacts with |
POLB | HPRD; |
interacts with |
POLI | MINT; |
interacts with |
POLL | MINT; |
interacts with |
PRKDC | MINT; |
interacts with |
RAN | BIOGRID; |
interacts with |
RECQL | MINT; |
interacts with |
RPA1 | MINT; |
interacts with |
TDP1 | MINT; |
interacts with |
TOP1 | MINT; |
interacts with |
TP53 | BIOGRID; |
interacts with |
XRCC5 | MINT; |
interacts with |
XRCC6 | MINT; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
E2F1 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
LIG3 | REACTOME; |
reacts with |
POLB | REACTOME; |
reacts with |
XRCC1 | REACTOME; |
state change |
LIG3 | REACTOME; |