Entrez Gene

Basic Information
Gene ID	637
Name	BID
Synonymous	FP497;BH3 interacting domain death agonist;BID;BH3 interacting domain death agonist
Definition	BH3-interacting domain death agonist\|BID isoform ES(1b)\|BID isoform L(2)\|BID isoform Si6\|Human BID coding sequence\|apoptic death agonist\|desmocollin type 4\|p22 BID
Position	22q11.1
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
Bid-isoform1(h) --Caspase-8(h)--> tBid-isoform1(h) + tBid-isoform1-p13(h) (processing)
A1(h) + Bid-isoform1(h) <==> A1(h):Bid-isoform1(h) (binding)
Bid-isoform1(h) --Caspase-2(h)--> tBid-isoform1(h) + protein remnants (processing)
Bid-isoform1(h) --Caspase-8(h)--> tBid-isoform1(h) + protein remnants (processing)
Bid-isoform1(h) + ATP --> Bid-isoform1(h){pS78} + ADP (phosphorylation)
BID(h) --> Bid-isoform1(h) (expression).
BID(h) --> Bid-isoform2(h) (expression).
BID(h) --> Bid-isoform3(h) (expression).
BID(h) --> Bid-isoform4(h) (expression).
Bid(h) --> tBid(h) + protein remnants (cleavage)
Bid(h) --> Bid-p15(h) + protein remnants (cleavage)
Bid(h) + ATP --ATM(h)--> Bid(h){pS78} + ADP (phosphorylation)
Bid(h) --Caspase-8(h)--> Bid-p15(h) + protein remnants (cleavage)
Bid(h) --> protein remnants (cleavage)
Bid(h) --Caspase-8(h)--> protein remnants (cleavage)
Bid(h) --Caspase-10(h)--> protein remnants (cleavage)
Bid(h) + Bak(h) <==> Bid(h):Bak(h) (binding)
Bid(h) --> Bid(h) (translocation)
Bid(h) --granzymeB(h)--> protein remnants (cleavage)
Bid(h) --CLN2-isoform1-p48(h)--> Bid-p15(h) + protein remnants (cleavage)
BID(h) --> Bid(h) (expression).
Daxx(h) --> Bid(h) (increase of processing)
Fas(h) --> Bid(h) (increase of processing)
Apo2L(m.s.) --/ Bid(h) (decrease of abundance)
Bid(h) --> Bid(h) (translocation)
Apo2L(h) --> Bid(h) (increase of cleavage)
Bcl-2(m.s.) --> Bid(h) (decrease of cleavage)

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
54	Phosphotyrosine.		Swiss-Prot 53.0
54	Phosphotyrosine	15592455	Phospho.ELM 6.0
78	Phosphoserine	16122426	Phospho.ELM 6.0

Transcription Factors [Top]