| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 5156 |
Name | PDGFRA |
Synonymous | CD140A|PDGFR-2|PDGFR2|RHEPDGFRA;platelet-derived growth factor receptor, alpha polypeptide;PDGFRA;platelet-derived growth factor receptor, alpha polypeptide |
Definition | CD140 antigen-like family member A|CD140a antigen|PDGF-R-alpha|PDGFR-alpha|PDGFRA/BCR fusion|alpha platelet-derived growth factor receptor|alpha-type platelet-derived growth factor receptor|platelet-derived growth factor alpha receptor|platelet-derived gr |
Position | 4q12 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | PDGFRalpha(h) + ATP --> PDGFRalpha(h){pY} + ADP (phosphorylation; automodification) | PDGFRA(h) --> PDGFRalpha(h) (expression). | PDGFRA(h) --> PDGFRalpha(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 42 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 76 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 103 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 179 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 353 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 359 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 458 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 468 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 849 | Phosphotyrosine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 | 762 | Phosphotyrosine (PDGFR alpha) | 9546424 | Phospho.ELM 6.0 | 754 | Phosphotyrosine (PDGFR alpha) | 7523122 | Phospho.ELM 6.0 | 767 | Phosphoserine | 8617789 | Phospho.ELM 6.0 | 572 | Phosphotyrosine | 11818394 | Phospho.ELM 6.0 | 574 | Phosphotyrosine | 11818394 | Phospho.ELM 6.0 | 720 | Phosphotyrosine | 11818394 | Phospho.ELM 6.0 | 731 | Phosphotyrosine | 11818394 | Phospho.ELM 6.0 | 742 | Phosphotyrosine | 11818394 | Phospho.ELM 6.0 | 1018 | Phosphotyrosine (PDGFR alpha) | 7535778 | Phospho.ELM 6.0 | 988 | Phosphotyrosine (PDGFR alpha) | 7535778 | Phospho.ELM 6.0 | 768 | Phosphotyrosine | 16497976 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr4 |
Promoter: 54788704 - 54790704 | Agilent_014791 |
chr4 |
Promoter: 54788704 - 54790704 | GoldenGate_Methylation_Cancer_Panel_I |
chr4 |
Promoter: 54788704 - 54790704 | Agilent_014791_44K |