| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 5156 |
Name | PDGFRA |
Synonymous | CD140A|PDGFR-2|PDGFR2|RHEPDGFRA;platelet-derived growth factor receptor, alpha polypeptide;PDGFRA;platelet-derived growth factor receptor, alpha polypeptide |
Definition | CD140 antigen-like family member A|CD140a antigen|PDGF-R-alpha|PDGFR-alpha|PDGFRA/BCR fusion|alpha platelet-derived growth factor receptor|alpha-type platelet-derived growth factor receptor|platelet-derived growth factor alpha receptor|platelet-derived gr |
Position | 4q12 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
CAV1 | NCI_NATURE; |
in same component |
CAV3 | NCI_NATURE; |
in same component |
CRKL | NCI_NATURE; |
in same component |
CRK | NCI_NATURE; |
in same component |
ITGAV | NCI_NATURE; |
in same component |
PDGFA | NCI_NATURE; |
in same component |
PDGFB | NCI_NATURE; |
in same component |
PDGFC | NCI_NATURE; |
in same component |
PDGFD | NCI_NATURE; |
in same component |
PDGFRB | NCI_NATURE; |
in same component |
PDGFRB | REACTOME; |
in same component |
RAPGEF1 | NCI_NATURE; |
in same component |
SHB | NCI_NATURE; |
in same component |
SHF | NCI_NATURE; |
interacts with |
CAV1 | BIOGRID; |
interacts with |
CAV1 | HPRD; |
interacts with |
CAV3 | BIOGRID; |
interacts with |
CBL | BIOGRID; |
interacts with |
CBL | HPRD; |
interacts with |
CRKL | BIOGRID; |
interacts with |
CRKL | HPRD; |
interacts with |
CRKL | MINT; |
interacts with |
CRK | BIOGRID; |
interacts with |
CRK | HPRD; |
interacts with |
CRK | MINT; |
interacts with |
GRB14 | HPRD; |
interacts with |
IFNG | NCI_NATURE; |
interacts with |
ITGAV | HPRD; |
interacts with |
ITGB3 | BIOGRID; |
interacts with |
ITGB3 | HPRD; |
interacts with |
JAK1 | HPRD; |
interacts with |
PDGFA | BIOGRID; |
interacts with |
PDGFA | HPRD; |
interacts with |
PDGFB | BIOGRID; |
interacts with |
PDGFB | HPRD; |
interacts with |
PDGFC | BIOGRID; |
interacts with |
PDGFC | HPRD; |
interacts with |
PDGFRB | BIOGRID; |
interacts with |
PDGFRB | HPRD; |
interacts with |
PIK3R1 | HPRD; |
interacts with |
PLCG1 | BIOGRID; |
interacts with |
PLCG1 | MINT; |
interacts with |
PTPN11 | HPRD; |
interacts with |
RAPGEF1 | HPRD; |
interacts with |
SHB | HPRD; |
interacts with |
SLC9A3R1 | BIOGRID; |
interacts with |
SLC9A3R1 | HPRD; |
interacts with |
SNX2 | BIOGRID; |
interacts with |
SNX2 | HPRD; |
interacts with |
SNX4 | BIOGRID; |
interacts with |
SNX6 | BIOGRID; |
interacts with |
STAT1 | HPRD; |
interacts with |
STAT3 | HPRD; |
interacts with |
STAT5A | HPRD; |
interacts with |
STAT5B | HPRD; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
ATF2 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
CAV1 | NCI_NATURE; |
reacts with |
CAV3 | NCI_NATURE; |
reacts with |
CRKL | NCI_NATURE; |
reacts with |
CRK | NCI_NATURE; |
reacts with |
ITGAV | NCI_NATURE; |
reacts with |
PDGFA | NCI_NATURE; |
reacts with |
PDGFB | NCI_NATURE; |
reacts with |
PDGFC | NCI_NATURE; |
reacts with |
PDGFD | NCI_NATURE; |
reacts with |
PDGFRA | NCI_NATURE; |
reacts with |
PDGFRA | REACTOME; |
reacts with |
PDGFRB | NCI_NATURE; |
reacts with |
PDGFRB | REACTOME; |
reacts with |
RAPGEF1 | NCI_NATURE; |
reacts with |
SHB | NCI_NATURE; |
reacts with |
SHF | NCI_NATURE; |
state change |
PDGFRA | REACTOME; |
state change |
PDGFRB | REACTOME; |