| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 4968 |
Name | OGG1 |
Synonymous | HMMH|HOGG1|MUTM|OGH1;8-oxoguanine DNA glycosylase;OGG1;8-oxoguanine DNA glycosylase |
Definition | 8-hydroxyguanine DNA glycosylase|AP lyase|DNA-apurinic or apyrimidinic site lyase|N-glycosylase/DNA lyase|OGG1 type 1f |
Position | 3p26.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | OGG1(h) + p300(h) <==> OGG1(h):p300(h) (binding) | OGG1(h) + SmF(h) <==> OGG1(h):SmF(h) (binding) | OGG1(h) --> OGG1(h) (expression). | OGG1-1A(h) + p34SEI-1(h) <==> OGG1-1A(h):p34SEI-1(h) (binding) | OGG1-1A(h) + p34SEI-1(h) <==> OGG1-1A(h):p34SEI-1(h) (binding) | OGG1-1A(h) + 2 ATP --> OGG1-1A(h){pS}{pT} + 2 ADP (phosphorylation) | OGG1-1A(h) + ATP --Cdk4(h)--> OGG1-1A(h){p} + ADP (phosphorylation) | OGG1-1A(h) + ATP --PKC(r)--> OGG1-1A(h){p} + ADP (phosphorylation) | OGG1-1A(h) + Abl(m.s.) <==> OGG1-1A(h):Abl(m.s.) (binding) | OGG1-1A(h) + OGG1(m.s.) <==> OGG1-1A(h):OGG1(m.s.) (binding) | OGG1-1A(h) + ATP --Abl(m.s.)--> OGG1-1A(h){pY} + ADP (phosphorylation) | OGG1-1A(h) + ATP --> OGG1-1A(h){pS} + ADP (phosphorylation) | OGG1-1A(h) + Cdk4(m.s.) <==> OGG1-1A(h):Cdk4(m.s.) (binding) | p300(m.s.) + OGG1-1A(h) <==> p300(m.s.):OGG1-1A(h) (binding) | OGG1-1A(h) + 2 acetyl-CoA --p300(h)--> OGG1-1A(h){aceK338}{aceK341} + 2 CoA (acetylation) | HDAC1(h) + OGG1-1A(h) <==> HDAC1(h):OGG1-1A(h) (binding) | OGG1-1A(h) + hdac2(h) <==> OGG1-1A(h):hdac2(h) (binding) | OGG1-1A(h) + HDAC3(h) <==> OGG1-1A(h):HDAC3(h) (binding) | OGG1-1A(h) + HDAC5(h) <==> OGG1-1A(h):HDAC5(h) (binding) | OGG1-1A(h) + hdac6(h) <==> OGG1-1A(h):hdac6(h) (binding) | OGG1(h) --> OGG1-1A(h) (expression). | OGG1-1A(h){ace} --HDAC1(h)--> OGG1-1A(h) + acetyl (deacetylation) | OGG1(h) --> OGG1-1B(h) (expression). | OGG1(h) --> OGG1-1C(h) (expression). | OGG1(h) --> OGG1-2A(h) (expression). | OGG1(h) --> OGG1-2B(h) (expression). | OGG1(h) --> OGG1-2C(h) (expression). | OGG1(h) --> OGG1-2D(h) (expression). | OGG1(h) --> OGG1-2E(h) (expression). |
|---|
Post Translational Modification [Top] | |||
There is no record for OGG1 | |||
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr3 |
Promoter: 9765154 - 9767154 | Agilent_014791 |
chr3 |
Promoter: 9764205 - 9766205 | GoldenGate_Methylation_Cancer_Panel_I |
chr3 |
Promoter: 9764205 - 9766205 | GoldenGate_Methylation_Cancer_Panel_I |
chr3 |
Promoter: 9764205 - 9766205 | GoldenGate_Methylation_Cancer_Panel_I |
chr3 |
Promoter: 9765161 - 9767161 | GoldenGate_Methylation_Cancer_Panel_I |
chr3 |
Promoter: 9765154 - 9767154 | GoldenGate_Methylation_Cancer_Panel_I |
chr3 |
Promoter: 9765154 - 9767154 | GoldenGate_Methylation_Cancer_Panel_I |
chr3 |
Promoter: 9765154 - 9767154 | GoldenGate_Methylation_Cancer_Panel_I |
chr3 |
Promoter: 9765154 - 9767154 | GoldenGate_Methylation_Cancer_Panel_I |
chr3 |
Promoter: 9765154 - 9767154 | GSE27584 |
chr3 |
Promoter: 9765154 - 9767154 | GSE27584 |
chr3 |
Promoter: 9765154 - 9767154 | GSE27584 |
chr3 |
Promoter: 9765154 - 9767154 | GSE27584 |
chr3 |
Promoter: 9764205 - 9766205 | GSE27584 |
chr3 |
Promoter: 9765161 - 9767161 | GSE27584 |
chr3 |
Promoter: 9764205 - 9766205 | GSE27584 |
chr3 |
Promoter: 9764205 - 9766205 | GSE27584 |
chr3 |
Promoter: 9765161 - 9767161 | Agilent_014791_44K |
chr3 |
Promoter: 9765154 - 9767154 | Agilent_014791_44K |
chr3 |
Promoter: 9765154 - 9767154 | Agilent_014791_44K |
chr3 |
Promoter: 9765154 - 9767154 | Agilent_014791_44K |
chr3 |
Promoter: 9765154 - 9767154 | Agilent_014791_44K |