| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 4968 |
Name | OGG1 |
Synonym | HMMH|HOGG1|MUTM|OGH1;8-oxoguanine DNA glycosylase;OGG1;8-oxoguanine DNA glycosylase |
Definition | 8-hydroxyguanine DNA glycosylase|AP lyase|DNA-apurinic or apyrimidinic site lyase|N-glycosylase/DNA lyase|OGG1 type 1f |
Position | 3p26.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Base excision repair;KEGG PATHWAY;hsa03410 |
Pathway | Cleavage of the damaged purine;PID Reactome;500910 |
Pathway | DNA Repair;Reactome;REACT:216 |
Pathway | Depurination;PID Reactome;500029 |
Pathway | Recognition and association of DNA glycosylase with site containing an affected purine;PID Reactome;500030 |
Pathway | Displacement of DNA glycosylase by APE1;PID Reactome;501000 |
Disease | ALS/amyotrophic lateral sclerosis;GAD |
Disease | esophageal cancer;GAD |
Disease | DNA repair;GAD |
Disease | lung cancer;GAD |
Disease | cervical cancer;GAD |
Disease | cytogenetic studies;GAD |
Disease | prostate cancer;GAD |
Disease | CANCER;GAD |
Disease | tooth loss;GAD |
Disease | Adenocarcinoma of the lung;GAD |
Disease | bladder cancer;GAD |
Disease | Renal cell carcinoma, clear cell, somatic;OMIM |
Disease | lung cancer risk;GAD |
Disease | upper aerodigestive tract cancer;GAD |
Disease | NEUROLOGICAL;GAD |
Disease | colorectal cancer;GAD |
External Links | |
Links to Entrez Gene | 4968 |
Links to all GeneRIF Items | 4968 |
Links to iHOP | 4968 |
Sequence Information | |
Nucleotide Sequence | >4968 : length: 1038 atgcctgcccgcgcgcttctgcccaggcgcatggggcatcgtactctagcctccactcct gccctgtgggcctccatcccgtgccctcgctctgagctgcgcctggacctggttctgcct tctggacaatctttccggtggagggagcaaagtcctgcacactggagtggtgtactagcg gatcaagtatggacactgactcagactgaggagcagctccactgcactgtgtaccgagga gacaagagccaggctagcaggcccacaccagacgagctggaggccgtgcgcaagtacttc cagctagatgttaccctggctcaactgtatcaccactggggttccgtggactcccacttc caagaggtggctcagaaattccaaggtgtgcgactgctgcgacaagaccccatcgaatgc cttttctcttttatctgttcctccaacaacaacatcgcccgcatcactggcatggtggag cggctgtgccaggcttttggacctcggctcatccagcttgatgatgtcacctaccatggc ttccccagcctgcaggccctggctgggccagaggtggaggctcatctcaggaagctgggc ctgggctatcgtgcccgttacgtgagtgccagtgcccgagccatcctggaagaacagggc gggctagcctggctgcagcagctacgagagtcctcatatgaggaggcccacaaggccctc tgcatcctgcctggagtgggcaccaaggtggctgactgcatctgcctgatggccctagac aagccccaggctgtgcccgtggatgtccatatgtggcacattgcccaacgtgactacagc tggcaccctaccacgtcccaggcgaagggaccgagcccccagaccaacaaggaactggga aactttttccggagcctgtggggaccttatgctggctgggcccaagcggtgctgttcagt gccgacctgcgccaatcccgccatgctcaggagccaccagcaaagcgcagaaagggttcc aaagggccggaaggctag |
Protein Sequence | >4968 : length: 345 MPARALLPRRMGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLA DQVWTLTQTEEQLHCTVYRGDKSQASRPTPDELEAVRKYFQLDVTLAQLYHHWGSVDSHF QEVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHG FPSLQALAGPEVEAHLRKLGLGYRARYVSASARAILEEQGGLAWLQQLRESSYEEAHKAL CILPGVGTKVADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELG NFFRSLWGPYAGWAQAVLFSADLRQSRHAQEPPAKRRKGSKGPEG |