| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 4747 |
Name | NEFL |
Synonymous | CMT1F|CMT2E|NF-L|NF68|NFL;neurofilament, light polypeptide;NEFL;neurofilament, light polypeptide |
Definition | 68 kDa neurofilament protein|light molecular weight neurofilament protein|neurofilament light polypeptide|neurofilament protein, light chain|neurofilament subunit NF-L|neurofilament triplet L protein|neurofilament, light polypeptide 68kDa|neurofilament-li |
Position | 8p21 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | hamartin(h) + NFL(h) <==> hamartin(h):NFL(h) (binding) | vimentin(h) + NFL(h) <==> vimentin(h):NFL(h) (binding) | NEFL(h) --> NFL(h) (expression). | Mi2-alpha(h) + NFL(h) <==> Mi2-alpha(h):NFL(h) (binding) | NFL(h) + BRD7(h) <==> NFL(h):BRD7(h) (binding) | NFL(h) + PIASy(h) <==> NFL(h):PIASy(h) (binding) | NFL(h) + vimentin(h) <==> NFL(h):vimentin(h) (binding) | NEFL(h) --> NFL(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 2 | N-acetylserine (By similarity). | Swiss-Prot 53.0 | 21 | O-linked (GlcNAc) (By similarity). | Swiss-Prot 53.0 | 27 | O-linked (GlcNAc) (By similarity). | Swiss-Prot 53.0 | 56 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 67 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 472 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr8 |
Promoter: 24869543 - 24871543 | Agilent_014791 |
chr8 |
Promoter: 24869543 - 24871543 | GoldenGate_Methylation_Cancer_Panel_I |
chr8 |
Promoter: 24869543 - 24871543 | GSE27584 |
chr8 |
Promoter: 24869543 - 24871543 | Agilent_014791_44K |