| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 4747 |
Name | NEFL |
Synonymous | CMT1F|CMT2E|NF-L|NF68|NFL;neurofilament, light polypeptide;NEFL;neurofilament, light polypeptide |
Definition | 68 kDa neurofilament protein|light molecular weight neurofilament protein|neurofilament light polypeptide|neurofilament protein, light chain|neurofilament subunit NF-L|neurofilament triplet L protein|neurofilament, light polypeptide 68kDa|neurofilament-li |
Position | 8p21 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
ACTN2 | REACTOME; |
in same component |
CALM1 | REACTOME; |
in same component |
DLG4 | REACTOME; |
in same component |
RASGRF1 | REACTOME; |
in same component |
RASGRF2 | REACTOME; |
interacts with |
ACTB | HPRD; |
interacts with |
APBB1 | HPRD; |
interacts with |
BRD7 | HPRD; |
interacts with |
BRD7 | MINT; |
interacts with |
CDK5RAP2 | MINT; |
interacts with |
CHD3 | MINT; |
interacts with |
CRYAB | HPRD; |
interacts with |
DNM1 | HPRD; |
interacts with |
GFAP | HPRD; |
interacts with |
GRIN1 | HPRD; |
interacts with |
HSP90AA1 | HPRD; |
interacts with |
HSPA8 | HPRD; |
interacts with |
MAP2 | BIOGRID; |
interacts with |
MAP3K5 | HPRD; |
interacts with |
MBP | HPRD; |
interacts with |
MTMR2 | HPRD; |
interacts with |
NEFH | BIOGRID; |
interacts with |
NEFH | HPRD; |
interacts with |
NSF | HPRD; |
interacts with |
PIAS4 | HPRD; |
interacts with |
PIAS4 | MINT; |
interacts with |
PKN1 | BIOGRID; |
interacts with |
PKN1 | HPRD; |
interacts with |
PPIA | HPRD; |
interacts with |
SPTAN1 | BIOGRID; |
interacts with |
SPTAN1 | HPRD; |
interacts with |
TSC1 | BIOGRID; |
interacts with |
TUBB | HPRD; |
interacts with |
UCHL1 | HPRD; |
interacts with |
UNG | HPRD; |
interacts with |
VIM | HPRD; |
interacts with |
VIM | MINT; |
interacts with |
YWHAG | HPRD; |
interacts with |
YWHAG | MINT; |
interacts with |
YWHAZ | HPRD; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
sequential catalysis |
ACTN2 | REACTOME; |
sequential catalysis |
DLG4 | REACTOME; |
sequential catalysis |
NEFL | REACTOME; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
ACTN2 | REACTOME; |
reacts with |
CALM1 | REACTOME; |
reacts with |
DLG4 | REACTOME; |
reacts with |
NEFL | REACTOME; |
reacts with |
RASGRF1 | REACTOME; |
reacts with |
RASGRF2 | REACTOME; |
state change |
ACTN2 | REACTOME; |
state change |
DLG4 | REACTOME; |
state change |
NEFL | REACTOME; |