Entrez Gene

Basic Information
Gene ID	4040
Name	LRP6
Synonymous	ADCAD2;low density lipoprotein receptor-related protein 6;LRP6;low density lipoprotein receptor-related protein 6
Definition	LRP-6\|low-density lipoprotein receptor-related protein 6
Position	12p13.2
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
Dkk-1(h) + LRP6(h) <==> Dkk-1(h):LRP6(h) (binding)
LRP6(h) + Wnt-1(m) <==> LRP6(h):Wnt-1(m) (binding)
Dkk-1(x) + LRP6(h) <==> Dkk-1(x):LRP6(h) (binding)
Dkk-2(m) + LRP6(h) <==> Dkk-2(m):LRP6(h) (binding)
Fz8(m) + Wnt-1(m) + LRP6(h) <==> Fz8(m):Wnt-1(m):LRP6(h) (binding)
axin(m) + LRP6(h) <==> axin(m):LRP6(h) (binding)
2 LRP6(h) <==> LRP6(h):LRP6(h) (binding)
LRP6(h) + Wnt-7A(h) + Fz5(h) <==> LRP6(h):Wnt-7A(h):Fz5(h) (binding)
LRP6(h) + Wnt-8A(x) + Fz5(h) <==> LRP6(h):Wnt-8A(x):Fz5(h) (binding)
LRP6(h) + Wnt-5A(x) + Fz5(h) <==> LRP6(h):Wnt-5A(x):Fz5(h) (binding)
LRP6(h) + Wnt-11(x) + Fz5(h) <==> LRP6(h):Wnt-11(x):Fz5(h) (binding)
LRP6(h) + Wnt-8A(x) + Fz4(h) <==> LRP6(h):Wnt-8A(x):Fz4(h) (binding)
LRP6(h) + ATP --> LRP6(h){pS1490} + ADP (phosphorylation)
Wnt-3A(m) + LRP6(h) <==> LRP6(h):Wnt-3A(m) (binding)
LRP6(h) --> LRP6(h) (expression).
LRP6(h) + ATP --> LRP6(h){pS1490} + ADP (phosphorylation)
LRP6(h) + FZ1(h) <==> LRP6(h):FZ1(h) (binding)
LRP6(h) --> LRP6(h) (expression).

Location (AA)	PTM type	Database
Post Translational Modification [Top]
42	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
81	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
281	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
433	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
486	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
692	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
859	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
865	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
926	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
1039	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0

Transcription Factors [Top]