| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 3973 |
Name | LHCGR |
Synonymous | HHG|LCGR|LGR2|LH/CG-R|LH/CGR|LHR|LHRHR|LSH-R|ULG5;luteinizing hormone/choriogonadotropin receptor;LHCGR;luteinizing hormone/choriogonadotropin receptor |
Definition | hypergonadotropic hypogonadism|lutropin-choriogonadotropic hormone receptor|lutropin/choriogonadotropin receptor |
Position | 2p21 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | LH-R-long(h) + 2 palmityl-CoA --> LH-R-long(h){palC643}{palC644} + 2 CoA (palmitoylation) | LH-R-long(h) + CG(h) <==> LH-R-long(h):CG(h) (binding) | LHCGR(h) --> LH-R-long(h) (expression). | LHCGR(h) --> LH-R-short(h) (expression). | LHCGR(h) --> LH-R(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 99 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 174 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 195 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 291 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 299 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 313 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 643 | S-palmitoyl cysteine. | Swiss-Prot 53.0 | 644 | S-palmitoyl cysteine. | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr2 |
Promoter: 48835867 - 48837867 | Agilent_014791 |
chr2 |
Promoter: 48835867 - 48837867 | GSE27584 |
chr2 |
Promoter: 48835867 - 48837867 | Agilent_014791_44K |