| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 3107 |
Name | HLA-C |
Synonymous | D6S204|HLA-JY3|HLC-C|PSORS1;major histocompatibility complex, class I, C;HLA-C;major histocompatibility complex, class I, C |
Definition | HLA class I histocompatibility antigen, C alpha chain|HLA class I histocompatibility antigen, Cw-1 alpha chain|MHC class I antigen heavy chain HLA-C|human leukocyte antigen-C alpha chain|major histocompatibility antigen HLA-C |
Position | 6p21.3 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | HLA-C(h) --> SHP-1(h){pY} (increase of phosphorylation) | HLA-C(h) + NKAT1(h) + NTP --> HLA-C(h):NKAT1(h){pY} + NDP (phosphorylation; binding) | HLA-C(h) --> NKAT1(h) (regulation of localization) | HLA-C(h) --> HLA-C(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 110 | N-linked (GlcNAc...) (By similarity). | Swiss-Prot 53.0 | 110 | N-linked (GlcNAc...) (By similarity). | Swiss-Prot 53.0 | 110 | N-linked (GlcNAc...) (By similarity). | Swiss-Prot 53.0 | 110 | N-linked (GlcNAc...) (By similarity). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr6 |
Promoter: 31347334 - 31349334 | Agilent_014791 |
chr6 |
Promoter: 31347334 - 31349334 | GSE27584 |
chr6 |
Promoter: 31347334 - 31349334 | Agilent_014791_44K |
chr6 |
Promoter: 31347334 - 31349334 | PMID:17318812 |