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Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3107

Name

HLA-C

Synonymous

D6S204|HLA-JY3|HLC-C|PSORS1;major histocompatibility complex, class I, C;HLA-C;major histocompatibility complex, class I, C

Definition

HLA class I histocompatibility antigen, C alpha chain|HLA class I histocompatibility antigen, Cw-1 alpha chain|MHC class I antigen heavy chain HLA-C|human leukocyte antigen-C alpha chain|major histocompatibility antigen HLA-C

Position

6p21.3

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

HLA-C(h) --> SHP-1(h){pY} (increase of phosphorylation)
HLA-C(h) + NKAT1(h) + NTP --> HLA-C(h):NKAT1(h){pY} + NDP (phosphorylation; binding)
HLA-C(h) --> NKAT1(h) (regulation of localization)
HLA-C(h) --> HLA-C(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

110N-linked (GlcNAc...) (By similarity).Swiss-Prot 53.0
110N-linked (GlcNAc...) (By similarity).Swiss-Prot 53.0
110N-linked (GlcNAc...) (By similarity).Swiss-Prot 53.0
110N-linked (GlcNAc...) (By similarity).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr6

Promoter: 31347334 - 31349334Agilent_014791

chr6

Promoter: 31347334 - 31349334GSE27584

chr6

Promoter: 31347334 - 31349334Agilent_014791_44K

chr6

Promoter: 31347334 - 31349334PMID:17318812


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