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Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3107

Name

HLA-C

Synonymous

D6S204|HLA-JY3|HLC-C|PSORS1;major histocompatibility complex, class I, C;HLA-C;major histocompatibility complex, class I, C

Definition

HLA class I histocompatibility antigen, C alpha chain|HLA class I histocompatibility antigen, Cw-1 alpha chain|MHC class I antigen heavy chain HLA-C|human leukocyte antigen-C alpha chain|major histocompatibility antigen HLA-C

Position

6p21.3

Gene Type

protein-coding

Gene Mutation:

PCGP germline mutation
PCGP somatic mutation
COSMIC somatic mutation

PCGP germline mutation   [Top]

There is no record for HLA-C

PCGP somatic mutation   [Top]

There is no record for HLA-C

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

c.362_363GG>AT; p.R121N; 6:31347085-31347086

 lungcarcinoma; non_small_cell_carcinoma

c.74-3delc; p.?;

NSmalignant_melanoma

c.289G>A; p.A97T;

haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; plasma_cell_myeloma

c.842A>G; p.Y281C;

upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinoma

c.486C>G; p.T162T;

livercarcinoma

c.463C>A; p.R155S;

skin; trunkmalignant_melanoma; nodular

c.1042G>A; p.A348T;

lungcarcinoma; adenocarcinoma

c.572G>C; p.W191S;

central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastoma

c.896A>G; p.E299G;

autonomic_ganglianeuroblastoma

c.97G>T; p.D33Y;

autonomic_ganglianeuroblastoma

c.623C>A; p.P208H;

autonomic_ganglianeuroblastoma

c.572G>C; p.W191S;

haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphoma

c.206G>A; p.G69E;

prostatecarcinoma

c.616G>A; p.A206T;

lungcarcinoma; adenocarcinoma

c.206G>A; p.G69E;

lungcarcinoma; adenocarcinoma

c.827G>T; p.G276V;

lung; right_lower_lobecarcinoma; adenocarcinoma

c.958G>T; p.V320F;

lungcarcinoma; squamous_cell_carcinoma

c.1075G>A; p.E359K;

lung; right_upper_lobecarcinoma; adenocarcinoma

c.206G>A; p.G69E;

lungcarcinoma; adenocarcinoma

c.425A>C; p.Y142S;

large_intestine; coloncarcinoma; adenocarcinoma

c.896A>G; p.E299G;

large_intestine; caecumcarcinoma; adenocarcinoma

c.175C>A; p.R59R;

large_intestine; coloncarcinoma; adenocarcinoma

c.167A>T; p.Q56L;

large_intestine; coloncarcinoma; adenocarcinoma

c.589G>A; p.E197K;

breastcarcinoma

c.355C>A; p.L119I;

large_intestine; caecumcarcinoma; adenocarcinoma

c.353C>T; p.T118I;

large_intestine; caecumcarcinoma; adenocarcinoma

c.773G>T; p.R258M;

large_intestine; coloncarcinoma; adenocarcinoma

c.355C>A; p.L119I;

large_intestine; coloncarcinoma; adenocarcinoma

c.353C>T; p.T118I;

large_intestine; coloncarcinoma; adenocarcinoma

c.728G>T; p.R243L;

large_intestine; coloncarcinoma; adenocarcinoma

c.367T>C; p.S123P;

large_intestine; coloncarcinoma; adenocarcinoma

c.427G>A; p.D143N;

large_intestine; caecumcarcinoma; adenocarcinoma

c.862G>A; p.E288K;

endometriumcarcinoma; endometrioid_carcinoma

c.539T>G; p.L180R;

breastcarcinoma

c.218C>A; p.A73E;

breastcarcinoma

c.361A>G; p.R121G;

endometriumcarcinoma; endometrioid_carcinoma

c.106G>A; p.V36M;

prostatecarcinoma; adenocarcinoma

c.674T>C; p.L225P;

large_intestine; caecumcarcinoma; adenocarcinoma

c.353C>T; p.T118I;

large_intestine; coloncarcinoma; adenocarcinoma

c.1071T>A; p.S357S;

kidneycarcinoma; clear_cell_renal_cell_carcinoma

c.273C>T; p.Y91Y;

breastcarcinoma

c.571T>G; p.W191G;

prostatecarcinoma; adenocarcinoma

c.390C>T; p.D130D;

urinary_tract; bladdercarcinoma

c.873A>G; p.Q291Q;

large_intestine; coloncarcinoma; adenocarcinoma

c.538C>T; p.L180L;

prostatecarcinoma; adenocarcinoma

c.187G>A; p.D63N;

urinary_tract; bladdercarcinoma

c.1037C>T; p.S346F;

skin; scalpcarcinoma; squamous_cell_carcinoma

c.1015+2T>C; p.?;

stomachadenocarcinoma

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