| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 2737 |
Name | GLI3 |
Synonymous | ACLS|GCPS|GLI3-190|GLI3FL|PAP-A|PAPA|PAPA1|PAPB|PHS|PPDIV;GLI family zinc finger 3;GLI3;GLI family zinc finger 3 |
Definition | GLI-Kruppel family member GLI3|glioma-associated oncogene family zinc finger 3|oncogene GLI3|transcriptional activator GLI3|zinc finger protein GLI3 |
Position | 7p13 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | gli3(h) + Su(fu)(h) <==> gli3(h):Su(fu)(h) (binding) | gli3(h) + CBP(m) <==> gli3(h):CBP(m) (binding) | c-Ski(h) + gli3(h) <==> c-Ski(h):gli3(h) (binding) | HDAC1(h) + gli3(h) <==> gli3(h):HDAC1(h) (binding) | Zic1(m) + gli3(h) <==> gli3(h):Zic1(m) (binding) | zic2(m) + gli3(h) <==> gli3(h):zic2(m) (binding) | Zic3(m) + gli3(h) <==> gli3(h):Zic3(m) (binding) | gli3(h) + Fu(h) <==> gli3(h):Fu(h) (binding) | gli3(h) --> BCL2(h) (DNA binding). | GLI3(h) --> gli3(h) (expression). | gli3(h) --/ BCL2(h) (DNA binding; transrepression). | gli3(h) --> GLI1(h) (DNA binding). | gli3(h) --> Gli1(m) (DNA binding; transactivation). | gli3(h) --> PTCH1(h) (DNA binding; transactivation). | GLI3(h) --> gli3(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 19 | Phosphoserine. | Swiss-Prot 53.0 | 19 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr7 |
Promoter: 42242637 - 42244637 | Agilent_014791 |
chr7 |
Promoter: 42242637 - 42244637 | GSE27584 |