Entrez Gene

Pediatric cancer gene database (Pedican) Home

General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information
Gene ID	2737
Name	GLI3
Synonymous	ACLS\|GCPS\|GLI3-190\|GLI3FL\|PAP-A\|PAPA\|PAPA1\|PAPB\|PHS\|PPDIV;GLI family zinc finger 3;GLI3;GLI family zinc finger 3
Definition	GLI-Kruppel family member GLI3\|glioma-associated oncogene family zinc finger 3\|oncogene GLI3\|transcriptional activator GLI3\|zinc finger protein GLI3
Position	7p13
Gene Type	protein-coding
Gene Interactions:	Physical Interaction Metabolic Interaction Signaling Interaction

Interaction Type	Interactor	Data Source
Physical Interaction [Top]
in same component	SPOP	NCI_NATURE;
in same component	SUFU	NCI_NATURE;
interacts with	BTRC	BIOGRID;
interacts with	CREBBP	BIOGRID;
interacts with	Crebbp	CELL_MAP;
interacts with	CREBBP	HPRD;
interacts with	HDAC1	BIOGRID;
interacts with	MED12	BIOGRID;
interacts with	Pias1	BIOGRID;
interacts with	Pias1	INTACT;
interacts with	SKI	BIOGRID;
interacts with	SKI	HPRD;
interacts with	SMAD1	HPRD;
interacts with	SMAD2	HPRD;
interacts with	SMAD4	HPRD;
interacts with	STK36	BIOGRID;
interacts with	STK36	CELL_MAP;
interacts with	STK36	HPRD;
interacts with	Sufu	BIOGRID;
interacts with	SUFU	BIOGRID;
interacts with	SUFU	CELL_MAP;
interacts with	SUFU	HPRD;
interacts with	Sufu	INTACT;
interacts with	TWIST1	HPRD;
interacts with	YWHAE	MINT;
interacts with	ZIC1	BIOGRID;
interacts with	ZIC1	HPRD;
interacts with	Zic1	MINT;
interacts with	ZIC2	BIOGRID;
interacts with	ZIC2	HPRD;
interacts with	Zic2	MINT;
interacts with	ZIC3	BIOGRID;
interacts with	ZIC3	HPRD;
interacts with	Zic3	MINT;

Interaction Type	Interactor	Data Source
Metabolic Interaction [Top]
metabolic catalysis	FBXW11	NCI_NATURE;
metabolic catalysis	SMO	NCI_NATURE;

Interaction Type	Interactor	Data Source
Signaling Interaction [Top]
reacts with	GLI3	NCI_NATURE;
reacts with	SPOP	NCI_NATURE;
reacts with	SUFU	NCI_NATURE;
state change	GSK3B	NCI_NATURE;
state change	HDAC1	NCI_NATURE;
state change	HDAC2	NCI_NATURE;
state change	IFT172	NCI_NATURE;
state change	IFT88	NCI_NATURE;
state change	KIF3A	NCI_NATURE;
state change	PRKACA	NCI_NATURE;
state change	RAB23	NCI_NATURE;
state change	RBBP4	NCI_NATURE;
state change	RBBP7	NCI_NATURE;
state change	SAP18	NCI_NATURE;
state change	SAP30	NCI_NATURE;
state change	SIN3A	NCI_NATURE;
state change	SIN3B	NCI_NATURE;
state change	SMO	NCI_NATURE;
state change	SUFU	NCI_NATURE;

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