Pediatric cancer gene database (Pedican) Home
Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

2068

Name

ERCC2

Synonymous

COFS2|EM9|TTD|XPD;excision repair cross-complementing rodent repair deficiency, complementation group 2;ERCC2;excision repair cross-complementing rodent repair deficiency, complementation group 2

Definition

BTF2 p80|CXPD|DNA excision repair protein ERCC-2|DNA repair protein complementing XP-D cells|TFIIH 80 kDa subunit|TFIIH basal transcription factor complex 80 kDa subunit|TFIIH basal transcription factor complex helicase XPD subunit|TFIIH basal transcripti

Position

19q13.3

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

TFIIH-p80(h) + NR1B1-isoform1(h) <==> TFIIH-p80(h):NR1B1-isoform1(h) (binding)
TFIIH-p80(h) + TFIIH-CAK(h) <==> TFIIH-p80(h):TFIIH-CAK(h) (binding)
CSB(h) + TFIIH-p90(h) + TFIIH-p80(h) + RPA116(h) <==> CSB(h):TFIIH-p90(h):TFIIH-p80(h):RPA116(h) (binding)
TFIIH-p80(h) + MO15(h) <==> TFIIH-p80(h):MO15(h) (binding)
ERCC2(h) --> TFIIH-p80(h) (expression).
ERCC2(h) --> TFIIH-p80(h) (expression).

Post Translational Modification   [Top]

There is no record for ERCC2

Methylation Profile   [Top]

Chromosome

Location

Source

chr19

Promoter: 50565169 - 50567169Agilent_014791

chr19

Promoter: 50565169 - 50567169GSE27584

chr19

Promoter: 50565169 - 50567169Agilent_014791_44K


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