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Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

2068

Name

ERCC2

Synonymous

COFS2|EM9|TTD|XPD;excision repair cross-complementing rodent repair deficiency, complementation group 2;ERCC2;excision repair cross-complementing rodent repair deficiency, complementation group 2

Definition

BTF2 p80|CXPD|DNA excision repair protein ERCC-2|DNA repair protein complementing XP-D cells|TFIIH 80 kDa subunit|TFIIH basal transcription factor complex 80 kDa subunit|TFIIH basal transcription factor complex helicase XPD subunit|TFIIH basal transcripti

Position

19q13.3

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 CCNHREACTOME;

in same component

 CCNT1REACTOME;

in same component

 CCNT2REACTOME;

in same component

 CDK7REACTOME;

in same component

 CDK9REACTOME;

in same component

 COBRA1REACTOME;

in same component

 CTDP1REACTOME;

in same component

 DDB1REACTOME;

in same component

 DDB2REACTOME;

in same component

 ELLREACTOME;

in same component

 ERCC1REACTOME;

in same component

 ERCC3REACTOME;

in same component

 ERCC4REACTOME;

in same component

 ERCC5REACTOME;

in same component

 ERCC6REACTOME;

in same component

 ERCC8REACTOME;

in same component

 GTF2A1REACTOME;

in same component

 GTF2A2REACTOME;

in same component

 GTF2BREACTOME;

in same component

 GTF2E1REACTOME;

in same component

 GTF2E2REACTOME;

in same component

 GTF2F1REACTOME;

in same component

 GTF2F2REACTOME;

in same component

 GTF2H1REACTOME;

in same component

 GTF2H2REACTOME;

in same component

 GTF2H3REACTOME;

in same component

 GTF2H4REACTOME;

in same component

 MNAT1REACTOME;

in same component

 POLR1AREACTOME;

in same component

 POLR1BREACTOME;

in same component

 POLR1CREACTOME;

in same component

 POLR1DREACTOME;

in same component

 POLR2AREACTOME;

in same component

 POLR2BREACTOME;

in same component

 POLR2CREACTOME;

in same component

 POLR2DREACTOME;

in same component

 POLR2EREACTOME;

in same component

 POLR2HREACTOME;

in same component

 POLR2IREACTOME;

in same component

 POLR2JREACTOME;

in same component

 POLR2KREACTOME;

in same component

 PTRFREACTOME;

in same component

 RAD23BREACTOME;

in same component

 RDBPREACTOME;

in same component

 RNGTTREACTOME;

in same component

 RNMTREACTOME;

in same component

 RPA1REACTOME;

in same component

 RPA2REACTOME;

in same component

 RPA3REACTOME;

in same component

 RRN3REACTOME;

in same component

 SSRP1REACTOME;

in same component

 SUPT16HREACTOME;

in same component

 TAF10REACTOME;

in same component

 TAF11REACTOME;

in same component

 TAF12REACTOME;

in same component

 TAF13REACTOME;

in same component

 TAF1AREACTOME;

in same component

 TAF1BREACTOME;

in same component

 TAF1CREACTOME;

in same component

 TAF1REACTOME;

in same component

 TAF4BREACTOME;

in same component

 TAF4REACTOME;

in same component

 TAF5REACTOME;

in same component

 TAF6REACTOME;

in same component

 TAF9REACTOME;

in same component

 TBPREACTOME;

in same component

 TCEA1REACTOME;

in same component

 TCEB1REACTOME;

in same component

 TCEB2REACTOME;

in same component

 TCEB3REACTOME;

in same component

 TH1LREACTOME;

in same component

 TTF1REACTOME;

in same component

 UBTFREACTOME;

in same component

 WHSC2REACTOME;

in same component

 XAB2REACTOME;

in same component

 XPAREACTOME;

in same component

 XPCREACTOME;

interacts with

 ATF7IPBIOGRID;

interacts with

 CCNHHPRD;

interacts with

 CDK7HPRD;

interacts with

 ERCC3BIOGRID;

interacts with

 ERCC3HPRD;

interacts with

 ERCC5BIOGRID;

interacts with

 ERCC5HPRD;

interacts with

 ERCC6BIOGRID;

interacts with

 GTF2H1BIOGRID;

interacts with

 GTF2H1HPRD;

interacts with

 GTF2H2BIOGRID;

interacts with

 GTF2H2HPRD;

interacts with

 GTF2H3HPRD;

interacts with

 GTF2H5HPRD;

interacts with

 HERC5BIOGRID;

interacts with

 ISG15BIOGRID;

interacts with

 MNAT1HPRD;

interacts with

 RAD51HPRD;

interacts with

 TP53BIOGRID;

interacts with

 TRIM25BIOGRID;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

sequential catalysis

 CCNHREACTOME;

sequential catalysis

 CDK7REACTOME;

sequential catalysis

 ERCC1REACTOME;

sequential catalysis

 ERCC2REACTOME;

sequential catalysis

 ERCC3REACTOME;

sequential catalysis

 ERCC4REACTOME;

sequential catalysis

 ERCC5REACTOME;

sequential catalysis

 ERCC6REACTOME;

sequential catalysis

 ERCC8REACTOME;

sequential catalysis

 GTF2H1REACTOME;

sequential catalysis

 GTF2H2REACTOME;

sequential catalysis

 GTF2H3REACTOME;

sequential catalysis

 GTF2H4REACTOME;

sequential catalysis

 MNAT1REACTOME;

sequential catalysis

 POLR1AREACTOME;

sequential catalysis

 POLR1BREACTOME;

sequential catalysis

 POLR1CREACTOME;

sequential catalysis

 POLR1DREACTOME;

sequential catalysis

 POLR2HREACTOME;

sequential catalysis

 POLR2KREACTOME;

sequential catalysis

 TAF1AREACTOME;

sequential catalysis

 TAF1BREACTOME;

sequential catalysis

 TAF1CREACTOME;

sequential catalysis

 TCEA1REACTOME;

sequential catalysis

 UBTFREACTOME;

sequential catalysis

 XAB2REACTOME;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 CCNHREACTOME;

reacts with

 CCNT1REACTOME;

reacts with

 CCNT2REACTOME;

reacts with

 CDK7REACTOME;

reacts with

 CDK9REACTOME;

reacts with

 COBRA1REACTOME;

reacts with

 CTDP1REACTOME;

reacts with

 DDB1REACTOME;

reacts with

 DDB2REACTOME;

reacts with

 ELLREACTOME;

reacts with

 ERCC1REACTOME;

reacts with

 ERCC2REACTOME;

reacts with

 ERCC3REACTOME;

reacts with

 ERCC4REACTOME;

reacts with

 ERCC5REACTOME;

reacts with

 ERCC6REACTOME;

reacts with

 ERCC8REACTOME;

reacts with

 GTF2A1REACTOME;

reacts with

 GTF2A2REACTOME;

reacts with

 GTF2BREACTOME;

reacts with

 GTF2E1REACTOME;

reacts with

 GTF2E2REACTOME;

reacts with

 GTF2F1REACTOME;

reacts with

 GTF2F2REACTOME;

reacts with

 GTF2H1REACTOME;

reacts with

 GTF2H2REACTOME;

reacts with

 GTF2H3REACTOME;

reacts with

 GTF2H4REACTOME;

reacts with

 MNAT1REACTOME;

reacts with

 NCBP1REACTOME;

reacts with

 NCBP2REACTOME;

reacts with

 POLR1AREACTOME;

reacts with

 POLR1BREACTOME;

reacts with

 POLR1CREACTOME;

reacts with

 POLR1DREACTOME;

reacts with

 POLR2AREACTOME;

reacts with

 POLR2BREACTOME;

reacts with

 POLR2CREACTOME;

reacts with

 POLR2DREACTOME;

reacts with

 POLR2EREACTOME;

reacts with

 POLR2HREACTOME;

reacts with

 POLR2IREACTOME;

reacts with

 POLR2JREACTOME;

reacts with

 POLR2KREACTOME;

reacts with

 PTRFREACTOME;

reacts with

 RAD23BREACTOME;

reacts with

 RDBPREACTOME;

reacts with

 RNGTTREACTOME;

reacts with

 RNMTREACTOME;

reacts with

 RPA1REACTOME;

reacts with

 RPA2REACTOME;

reacts with

 RPA3REACTOME;

reacts with

 RRN3REACTOME;

reacts with

 SSRP1REACTOME;

reacts with

 SUPT16HREACTOME;

reacts with

 TAF10REACTOME;

reacts with

 TAF11REACTOME;

reacts with

 TAF12REACTOME;

reacts with

 TAF13REACTOME;

reacts with

 TAF1AREACTOME;

reacts with

 TAF1BREACTOME;

reacts with

 TAF1CREACTOME;

reacts with

 TAF1REACTOME;

reacts with

 TAF4BREACTOME;

reacts with

 TAF4REACTOME;

reacts with

 TAF5REACTOME;

reacts with

 TAF6REACTOME;

reacts with

 TAF9REACTOME;

reacts with

 TBPREACTOME;

reacts with

 TCEA1REACTOME;

reacts with

 TCEB1REACTOME;

reacts with

 TCEB2REACTOME;

reacts with

 TCEB3REACTOME;

reacts with

 TH1LREACTOME;

reacts with

 TTF1REACTOME;

reacts with

 UBTFREACTOME;

reacts with

 WHSC2REACTOME;

reacts with

 XAB2REACTOME;

reacts with

 XPAREACTOME;

reacts with

 XPCREACTOME;

state change

 CCNHREACTOME;

state change

 CDK7REACTOME;

state change

 DDB1REACTOME;

state change

 DDB2REACTOME;

state change

 ERCC1REACTOME;

state change

 ERCC2REACTOME;

state change

 ERCC3REACTOME;

state change

 ERCC4REACTOME;

state change

 ERCC5REACTOME;

state change

 GTF2F1REACTOME;

state change

 GTF2F2REACTOME;

state change

 GTF2H1REACTOME;

state change

 GTF2H2REACTOME;

state change

 GTF2H3REACTOME;

state change

 GTF2H4REACTOME;

state change

 MNAT1REACTOME;

state change

 POLR2AREACTOME;

state change

 POLR2BREACTOME;

state change

 POLR2CREACTOME;

state change

 POLR2DREACTOME;

state change

 POLR2EREACTOME;

state change

 POLR2HREACTOME;

state change

 POLR2IREACTOME;

state change

 POLR2JREACTOME;

state change

 POLR2KREACTOME;

state change

 RAD23BREACTOME;

state change

 RNGTTREACTOME;

state change

 RNMTREACTOME;

state change

 RPA1REACTOME;

state change

 RPA2REACTOME;

state change

 RPA3REACTOME;

state change

 XPAREACTOME;

state change

 XPCREACTOME;

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