| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 161742 |
Name | SPRED1 |
Synonymous | NFLS;sprouty-related, EVH1 domain containing 1;SPRED1;sprouty-related, EVH1 domain containing 1 |
Definition | EVH1/Sprouty domain containing protein|hSpred1|spred-1|sprouty-related, EVH1 domain-containing protein 1|suppressor of Ras/MAPK activation |
Position | 15q14 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | Spred-1(h) --> ERK2(m.s.){p} (decrease of phosphorylation) | Spred-1(h) + 2 ATP --> Spred-1(h){pS}{pT} + 2 ADP (phosphorylation) | Spred-1(h) --> Ral(m.s.):Rap1(h):GTP (decrease of binding) | Spred-1(h) --> Raf-1(h):Ras(h):GTP (decrease of binding) | Spred-1(h) + Spred-2(h) <==> Spred-1(h):Spred-2(h) (binding) | Spred-1(h) + ATP --> Spred-1(h){pY} + ADP (phosphorylation) | Spred-1(h) + n ubiquitin(h) --> Spred-1(h){ub}n (ubiquitination) | SPRED1(h) --> Spred-1(h) (expression). | SPRED1(h) --> Spred-1(h) (expression). |
|---|
Post Translational Modification [Top] | |||
There is no record for SPRED1 | |||
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr15 |
Promoter: 36330308 - 36332308 | Agilent_014791 |
chr15 |
Promoter: 36330308 - 36332308 | GSE27584 |
chr15 |
Promoter: 36330308 - 36332308 | Agilent_014791_44K |