| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 4299 |
Name | AFF1 |
Synonymous | AF4|MLLT2|PBM1;AF4/FMR2 family, member 1;AFF1;AF4/FMR2 family, member 1 |
Definition | AF4/FMR2 family member 1|ALL1-fused gene from chromosome 4 protein|myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 2|pre-B-cell monocytic leukemia partner 1|protein AF-4|proto-oncogene AF4 |
Position | 4q21 |
Gene Type | protein-coding |
Gene Mutation: | PCGP germline mutation PCGP somatic mutation COSMIC somatic mutation |
PCGP germline mutation [Top] | ||
There is no record for AFF1 | ||
PCGP somatic mutation [Top] | ||
Variant (Variant; Chr; Position) | Genotype (MutationType; MutationClass; ReferenceAllele; Genotype; Origin) | Disease (CancerType; ValidationStatus; SequencingType) |
|---|---|---|
AFF1_H700Q; chr4; 88036106 |
SUB; MISSENSE; C; C/G; SOMATIC | RHB; PUTATIVE-HQ; EXOME |
COSMIC somatic mutation [Top] | ||
Mutation (CDS; AA; Chr) | Site | Histology |
|---|---|---|
c.3610C>A; p.Q1204K; 4:88275854-88275854 |
breast | carcinoma; ductal_carcinoma |
c.1025C>A; p.S342Y; |
large_intestine; colon | carcinoma; adenocarcinoma |
c.2679C>T; p.G893G; |
large_intestine; rectum | carcinoma; adenocarcinoma |