| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 4049 |
Name | LTA |
Synonymous | LT|TNFB|TNFSF1;lymphotoxin alpha (TNF superfamily, member 1);LTA;lymphotoxin alpha (TNF superfamily, member 1) |
Definition | LT-alpha|TNF-beta|lymphotoxin-alpha|tumor necrosis factor beta|tumor necrosis factor ligand superfamily member 1 |
Position | 6p21.3 |
Gene Type | protein-coding |
Gene Mutation: | PCGP germline mutation PCGP somatic mutation COSMIC somatic mutation |
PCGP germline mutation [Top] | ||
There is no record for LTA | ||
PCGP somatic mutation [Top] | ||
There is no record for LTA | ||
COSMIC somatic mutation [Top] | ||
Mutation (CDS; AA; Chr) | Site | Histology |
|---|---|---|
c.400G>T; p.E134*; |
pancreas | carcinoma; acinar_carcinoma |
c.594C>G; p.V198V; |
NS | NS |
c.594C>G; p.V198V; |
NS | NS |
c.594C>G; p.V198V; |
NS | NS |
c.594C>G; p.V198V; |
NS | NS |
c.3G>A; p.M1I; |
upper_aerodigestive_tract; mouth | carcinoma; squamous_cell_carcinoma |
c.388T>C; p.Y130H; |
lung | carcinoma; squamous_cell_carcinoma |
c.285C>A; p.S95R; |
ovary | carcinoma; serous_carcinoma |
c.300G>C; p.L100L; |
ovary | carcinoma; serous_carcinoma |
c.225C>G; p.N75K; |
lung | carcinoma; squamous_cell_carcinoma |
c.516G>A; p.A172A; |
endometrium | carcinoma; endometrioid_carcinoma |
c.610G>A; p.A204T; |
large_intestine; colon | carcinoma; adenocarcinoma |
c.295C>A; p.L99I; |
endometrium | carcinoma; endometrioid_carcinoma |
c.533G>T; p.G178V; |
endometrium | carcinoma; endometrioid_carcinoma |
c.427C>G; p.P143A; |
kidney | carcinoma; clear_cell_renal_cell_carcinoma |
c.248C>T; p.T83M; |
endometrium | carcinoma; endometrioid_carcinoma |
c.250G>A; p.D84N; |
breast | carcinoma |
c.327C>G; p.V109V; |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm; diffuse_large_B_cell_lymphoma |