| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 4049 |
Name | LTA |
Synonym | LT|TNFB|TNFSF1;lymphotoxin alpha (TNF superfamily, member 1);LTA;lymphotoxin alpha (TNF superfamily, member 1) |
Definition | LT-alpha|TNF-beta|lymphotoxin-alpha|tumor necrosis factor beta|tumor necrosis factor ligand superfamily member 1 |
Position | 6p21.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | IL2 signaling events mediated by STAT5;PID Curated;200158 |
Pathway | Type I diabetes mellitus;KEGG PATHWAY;hsa04940 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Pathway | Apoptosis signaling pathway;PANTHER;P00006 |
Pathway | IL4-mediated signaling events;PID Curated;200018 |
Pathway | tnfr2 signaling pathway;PID BioCarta;100014 |
Disease | atopy;GAD |
Disease | Premature birth;FunDO |
Disease | oral submucous fibrosis;GAD |
Disease | endometriosis;GAD |
Disease | Alzheimer's disease;GAD |
Disease | Migraine;FunDO |
Disease | Lung cancer;FunDO |
Disease | Melanoma;FunDO |
Disease | diabetes, type 2;GAD |
Disease | urinary tract infections after renal transplantation;GAD |
Disease | Purpura, Thrombocytopenic, Idiopathic;FunDO |
Disease | Psoriasis;FunDO |
Disease | Breast cancer;FunDO |
Disease | Stomach cancer;FunDO |
Disease | bronchiectatic disease;GAD |
Disease | intima-media thickness;GAD |
Disease | hepatitis B;GAD |
Disease | DEVELOPMENTAL;GAD |
Disease | hypertension;GAD |
Disease | serum tumor necrosis factor-alpha levels;GAD |
Disease | Amnionitis;FunDO |
Disease | Leprosy;FunDO |
Disease | atherosclerosis, coronary;GAD |
Disease | IMMUNE;GAD |
Disease | Multiple myeloma;FunDO |
Disease | Brain Ischemia;GAD |
Disease | Rheumatoid arthritis;FunDO |
Disease | rheumatoid arthritis;GAD |
Disease | testicular cancer;GAD |
Disease | Sarcoidosis;FunDO |
Disease | Peptic ulcer;FunDO |
Disease | METABOLIC;GAD |
Disease | chronic immune thrombocytopenic purpura.;GAD |
Disease | Schizophrenia;FunDO |
Disease | Asthma;GAD |
Disease | Postoperative infectious complications;GAD |
Disease | Colon cancer;FunDO |
Disease | Osteoporosis;GAD |
Disease | sepsis;GAD |
Disease | Diabetes mellitus;FunDO |
Disease | diabetes, type 1;GAD |
Disease | gastric cancer;GAD |
Disease | REPRODUCTION;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Stroke;GAD |
Disease | Stroke;FunDO |
Disease | CANCER;GAD |
Disease | Myocardial Infarction;GAD |
Disease | Bladder cancer;FunDO |
Disease | Psoriatic arthritis, susceptibility to;OMIM |
Disease | Endometriosis;FunDO |
Disease | INFECTION;GAD |
Disease | NEUROLOGICAL;GAD |
Disease | palmoplantar pustulosis;GAD |
Disease | Hypertension;FunDO |
Disease | vasopressor infusion requirement;GAD |
Disease | Enteritis;FunDO |
Disease | Pancreatitis;FunDO |
Disease | Asthma;FunDO |
Disease | myelopathy, HTLV-1 associated;GAD |
Disease | chronic obstructive pulmonary disease/COPD;GAD |
Disease | complications after major abdominal operations;GAD |
Disease | Myocardial infarction, susceptibility to;OMIM |
Disease | limb deficiency anomalies;GAD |
Disease | erythrocyte catalase activity;GAD |
Disease | myocardial infarct;GAD |
Disease | Leprosy, susceptibility to, 4;OMIM |
Disease | Lupus;GAD |
Disease | Atherosclerosis;FunDO |
External Links | |
Links to Entrez Gene | 4049 |
Links to all GeneRIF Items | 4049 |
Links to iHOP | 4049 |
Sequence Information | |
Nucleotide Sequence | >4049 : length: 618 atgacaccacctgaacgtctcttcctcccaagggtgtgtggcaccaccctacacctcctc cttctggggctgctgctggttctgctgcctggggcccaggggctccctggtgttggcctc acaccttcagctgcccagactgcccgtcagcaccccaagatgcatcttgcccacagcacc ctcaaacctgctgctcacctcattggagaccccagcaagcagaactcactgctctggaga gcaaacacggaccgtgccttcctccaggatggtttctccttgagcaacaattctctcctg gtccccaccagtggcatctacttcgtctactcccaggtggtcttctctgggaaagcctac tctcccaaggccacctcctccccactctacctggcccatgaggtccagctcttctcctcc cagtaccccttccatgtgcctctcctcagctcccagaagatggtgtatccagggctgcag gaaccctggctgcactcgatgtaccacggggctgcgttccagctcacccagggagaccag ctatccacccacacagatggcatcccccacctagtcctcagccctagtactgtcttcttt ggagccttcgctctgtag |
Protein Sequence | >4049 : length: 205 MTPPERLFLPRVCGTTLHLLLLGLLLVLLPGAQGLPGVGLTPSAAQTARQHPKMHLAHST LKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLSNNSLLVPTSGIYFVYSQVVFSGKAY SPKATSSPLYLAHEVQLFSSQYPFHVPLLSSQKMVYPGLQEPWLHSMYHGAAFQLTQGDQ LSTHTDGIPHLVLSPSTVFFGAFAL |