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Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

23493

Name

HEY2

Synonymous

CHF1|GRIDLOCK|GRL|HERP1|HESR2|HRT2|bHLHb32;hairy/enhancer-of-split related with YRPW motif 2;HEY2;hairy/enhancer-of-split related with YRPW motif 2

Definition

HES-related repressor protein 1|HES-related repressor protein 2|HESR-2|HRT-2|cardiovascular basic helix-loop-helix factor 1|cardiovascular helix-loop-helix factor 1|class B basic helix-loop-helix protein 32|hCHF1|hHRT2|hairy and enhancer of split-related

Position

6q21

Gene Type

protein-coding

Gene Mutation:

PCGP germline mutation
PCGP somatic mutation
COSMIC somatic mutation

PCGP germline mutation   [Top]

There is no record for HEY2

PCGP somatic mutation   [Top]

There is no record for HEY2

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

c.676_678delCTC; p.L227delL;

livercarcinoma; hepatocellular_carcinoma

c.546G>T; p.P182P;

breastcarcinoma; ER-PR-positive_carcinoma

c.346G>A; p.A116T;

large_intestine; coloncarcinoma; adenocarcinoma

c.360C>G; p.D120E;

large_intestine; coloncarcinoma; adenocarcinoma

c.401C>T; p.A134V;

large_intestine; colonadenoma

c.788C>T; p.T263I;

oesophaguscarcinoma; adenocarcinoma

c.179G>A; p.R60H;

oesophagus; lower_thirdcarcinoma; adenocarcinoma

c.876C>T; p.N292N;

oesophaguscarcinoma; adenocarcinoma

c.715C>T; p.R239*;

oesophaguscarcinoma; adenocarcinoma

c.584delC; p.L196fs*>142;

livercarcinoma

c.714C>A; p.L238L;

lungcarcinoma; adenocarcinoma

c.915G>A; p.P305P;

lungcarcinoma; adenocarcinoma

c.736G>A; p.V246I;

lungcarcinoma; adenocarcinoma

c.923C>T; p.S308L;

boneosteosarcoma

c.401C>T; p.A134V;

lungcarcinoma; small_cell_carcinoma

c.921G>A; p.L307L;

prostateadenoma

c.340G>C; p.A114P;

lungcarcinoma; squamous_cell_carcinoma

c.852G>T; p.G284G;

lungcarcinoma; adenocarcinoma

c.739G>A; p.A247T;

lungcarcinoma; adenocarcinoma

c.735C>T; p.S245S;

lung; right_upper_lobecarcinoma; adenocarcinoma

c.990G>T; p.W330C;

lungcarcinoma; adenocarcinoma

c.690G>A; p.T230T;

lung; right_upper_lobecarcinoma; adenocarcinoma

c.361T>C; p.F121L;

lung; right_upper_lobecarcinoma; adenocarcinoma

c.378C>T; p.F126F;

large_intestine; coloncarcinoma; adenocarcinoma

c.454C>T; p.R152W;

large_intestine; caecumcarcinoma; adenocarcinoma

c.340G>A; p.A114T;

large_intestine; coloncarcinoma; adenocarcinoma

c.418G>A; p.V140M;

large_intestine; coloncarcinoma; adenocarcinoma

c.118_119insCAA; p.T43_S44insT;

large_intestine; coloncarcinoma; adenocarcinoma

c.179G>A; p.R60H;

large_intestine; rectumcarcinoma; adenocarcinoma

c.469C>A; p.L157I;

large_intestine; rectumcarcinoma; adenocarcinoma

c.848C>T; p.A283V;

large_intestine; rectumcarcinoma; adenocarcinoma

c.401C>T; p.A134V;

large_intestine; rectumcarcinoma; adenocarcinoma

c.638C>T; p.S213F;

breastcarcinoma

c.865C>T; p.L289F;

endometriumcarcinoma; endometrioid_carcinoma

c.888A>G; p.A296A;

large_intestine; caecumcarcinoma; adenocarcinoma

c.576G>C; p.L192L;

endometriumcarcinoma; endometrioid_carcinoma

c.805G>A; p.A269T;

endometriumcarcinoma; endometrioid_carcinoma

c.878C>A; p.A293E;

endometriumcarcinoma; endometrioid_carcinoma

c.328_328+27del28; p.?;

endometriumcarcinoma; endometrioid_carcinoma

c.549T>G; p.H183Q;

endometriumcarcinoma; endometrioid_carcinoma

c.876C>T; p.N292N;

large_intestine; coloncarcinoma; adenocarcinoma

c.666C>T; p.H222H;

prostatecarcinoma

c.683C>T; p.T228M;

kidneycarcinoma; clear_cell_renal_cell_carcinoma

c.528C>T; p.H176H;

stomachadenocarcinoma

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