Entrez Gene

Pediatric cancer gene database (Pedican) Home

General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information
Gene ID	23493
Name	HEY2
Synonymous	CHF1\|GRIDLOCK\|GRL\|HERP1\|HESR2\|HRT2\|bHLHb32;hairy/enhancer-of-split related with YRPW motif 2;HEY2;hairy/enhancer-of-split related with YRPW motif 2
Definition	HES-related repressor protein 1\|HES-related repressor protein 2\|HESR-2\|HRT-2\|cardiovascular basic helix-loop-helix factor 1\|cardiovascular helix-loop-helix factor 1\|class B basic helix-loop-helix protein 32\|hCHF1\|hHRT2\|hairy and enhancer of split-related
Position	6q21
Gene Type	protein-coding
Gene Interactions:	Physical Interaction Metabolic Interaction Signaling Interaction

Interaction Type	Interactor	Data Source
Physical Interaction [Top]
in same component	ARNT	NCI_NATURE;
in same component	GATA4	NCI_NATURE;
in same component	GATA6	NCI_NATURE;
in same component	RUNX2	NCI_NATURE;
interacts with	BTRC	BIOGRID;
interacts with	CASP3	BIOGRID;
interacts with	HAND1	BIOGRID;
interacts with	HAND1	HPRD;
interacts with	HDAC1	BIOGRID;
interacts with	HDAC9	BIOGRID;
interacts with	HES1	BIOGRID;
interacts with	HES1	HPRD;
interacts with	NCOR1	BIOGRID;
interacts with	NCOR1	HPRD;
interacts with	PLSCR1	BIOGRID;
interacts with	PLSCR1	HPRD;
interacts with	PLSCR1	MINT;
interacts with	SIN3A	BIOGRID;
interacts with	SIN3A	HPRD;
interacts with	SIRT1	BIOGRID;
interacts with	SIRT1	HPRD;

Interaction Type	Interactor	Data Source
Metabolic Interaction [Top]
metabolic catalysis	NOTCH1	NCI_NATURE;
metabolic catalysis	RBPJ	NCI_NATURE;

Interaction Type	Interactor	Data Source
Signaling Interaction [Top]
reacts with	ARNT	NCI_NATURE;
reacts with	GATA4	NCI_NATURE;
reacts with	GATA6	NCI_NATURE;
reacts with	HEY2	NCI_NATURE;
reacts with	HIF1A	NCI_NATURE;
reacts with	RUNX2	NCI_NATURE;

')