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Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

22974

Name

TPX2

Synonymous

C20orf1|C20orf2|DIL-2|DIL2|FLS353|GD:C20orf1|HCA519|HCTP4|REPP86|p100;TPX2, microtubule-associated, homolog (Xenopus laevis);TPX2;TPX2, microtubule-associated, homolog (Xenopus laevis)

Definition

TPX2, microtubule-associated protein homolog|differentially expressed in cancerous and non-cancerous lung cells 2|differentially expressed in lung cells|hepatocellular carcinoma-associated antigen 519|preferentially expressed in colorectal cancer|protein

Position

20q11.2

Gene Type

protein-coding

Gene Mutation:

PCGP germline mutation
PCGP somatic mutation
COSMIC somatic mutation

PCGP germline mutation   [Top]

There is no record for TPX2

PCGP somatic mutation   [Top]

There is no record for TPX2

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

c.1843G>A; p.E615K;

large_intestine; coloncarcinoma; adenocarcinoma

c.799C>T; p.R267*;

large_intestine; coloncarcinoma; adenocarcinoma

c.1314G>T; p.E438D;

large_intestine; coloncarcinoma; adenocarcinoma

c.637C>T; p.Q213*;

oesophaguscarcinoma; adenocarcinoma

c.902G>A; p.C301Y;

lungcarcinoma; adenocarcinoma

c.229+1G>A; p.?;

livercarcinoma

c.1109C>A; p.P370H;

large_intestine; coloncarcinoma

c.268C>G; p.L90V;

upper_aerodigestive_tract; pharynxcarcinoma; squamous_cell_carcinoma

c.299G>T; p.C100F;

upper_aerodigestive_tract; larynxcarcinoma; squamous_cell_carcinoma

c.670G>T; p.E224*;

lungcarcinoma; large_cell_carcinoma

c.739G>T; p.V247L;

lungcarcinoma; adenocarcinoma

c.609G>A; p.K203K;

lungcarcinoma; adenocarcinoma

c.826G>A; p.E276K;

lungcarcinoma; adenocarcinoma

c.2230C>T; p.R744*;

lungcarcinoma; adenocarcinoma

c.1516G>T; p.D506Y;

lungcarcinoma; adenocarcinoma

c.1391C>A; p.T464N; 20:29835363-29835363

 large_intestine; coloncarcinoma; adenocarcinoma

c.452T>C; p.I151T; 20:29821902-29821902

 ovarycarcinoma; serous_carcinoma

c.2138A>G; p.H713R;

lungcarcinoma; adenocarcinoma

c.343G>A; p.A115T;

lungcarcinoma; adenocarcinoma

c.1632C>G; p.D544E;

lung; right_upper_lobecarcinoma; adenocarcinoma

c.899G>T; p.G300V;

lungcarcinoma; adenocarcinoma

c.1969C>T; p.Q657*;

lung; right_upper_lobecarcinoma; adenocarcinoma

c.1969C>T; p.Q657*;

lung; right_upper_lobecarcinoma; adenocarcinoma

c.508G>C; p.E170Q;

lung; right_upper_lobecarcinoma; adenocarcinoma

c.1677G>T; p.Q559H;

lung; right_upper_lobecarcinoma; adenocarcinoma

c.48C>T; p.F16F;

lung; right_lower_lobecarcinoma; adenocarcinoma

c.78A>T; p.G26G;

lung; right_upper_lobecarcinoma; adenocarcinoma

c.1882C>A; p.R628S;

lungcarcinoma; squamous_cell_carcinoma

c.158G>T; p.G53V;

lung; right_upper_lobecarcinoma; adenocarcinoma

c.1486C>T; p.R496*;

large_intestine; coloncarcinoma; adenocarcinoma

c.262G>T; p.E88*;

large_intestine; coloncarcinoma; adenocarcinoma

c.417A>C; p.K139N;

large_intestine; caecumcarcinoma; adenocarcinoma

c.1669G>T; p.E557*;

large_intestine; caecumcarcinoma; adenocarcinoma

c.939G>T; p.K313N;

large_intestine; coloncarcinoma; adenocarcinoma

c.1022G>T; p.R341I;

large_intestine; coloncarcinoma; adenocarcinoma

c.1411G>T; p.V471L;

large_intestine; caecumcarcinoma; adenocarcinoma

c.2168G>A; p.G723D;

large_intestine; caecumcarcinoma; adenocarcinoma

c.1137G>T; p.R379R;

large_intestine; rectumcarcinoma; adenocarcinoma

c.174A>T; p.K58N;

large_intestine; rectumcarcinoma; adenocarcinoma

c.107-1G>T; p.?;

endometriumcarcinoma; endometrioid_carcinoma

c.1294G>A; p.G432S;

endometriumcarcinoma; endometrioid_carcinoma

c.1306G>A; p.E436K;

endometriumcarcinoma; endometrioid_carcinoma

c.1504G>T; p.D502Y;

endometriumcarcinoma; endometrioid_carcinoma

c.546G>T; p.K182N;

endometriumcarcinoma; endometrioid_carcinoma

c.1486C>T; p.R496*;

endometriumcarcinoma; endometrioid_carcinoma

c.1392T>A; p.T464T;

large_intestine; caecumcarcinoma; adenocarcinoma

c.1260G>T; p.K420N;

endometriumcarcinoma; endometrioid_carcinoma

c.2231G>A; p.R744Q;

endometriumcarcinoma; endometrioid_carcinoma

c.1486C>T; p.R496*;

endometriumcarcinoma; endometrioid_carcinoma

c.214A>G; p.T72A;

endometriumcarcinoma; endometrioid_carcinoma

c.1486C>T; p.R496*;

endometriumcarcinoma; endometrioid_carcinoma

c.839A>C; p.E280A;

kidneycarcinoma; clear_cell_renal_cell_carcinoma

c.71A>G; p.D24G;

kidneycarcinoma; clear_cell_renal_cell_carcinoma

c.1669G>T; p.E557*;

endometriumcarcinoma; endometrioid_carcinoma

c.863G>A; p.R288Q;

large_intestine; coloncarcinoma; adenocarcinoma

c.2061G>A; p.Q687Q;

endometriumcarcinoma; endometrioid_carcinoma

c.1945G>A; p.E649K;

urinary_tract; bladdercarcinoma

c.1903C>G; p.Q635E;

cervixcarcinoma; squamous_cell_carcinoma

c.631G>T; p.E211*;

prostatecarcinoma; adenocarcinoma

c.670G>T; p.E224*;

central_nervous_system; brainglioma

c.880C>T; p.P294S;

skin; scalpcarcinoma; squamous_cell_carcinoma

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