| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 1646 |
Name | AKR1C2 |
Synonymous | AKR1C-pseudo|BABP|DD|DD2|DDH2|HAKRD|HBAB|MCDR2|SRXY8;aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III);AKR1C2;aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) |
Definition | 3-alpha-HSD3|DD-2|DD/BABP|aldo-keto reductase family 1 member C2|chlordecone reductase homolog HAKRD|pseudo-chlordecone reductase|trans-1,2-dihydrobenzene-1,2-diol dehydrogenase|type II dihydrodiol dehydrogenase |
Position | 10p15-p14 |
Gene Type | protein-coding |
Gene Mutation: | PCGP germline mutation PCGP somatic mutation COSMIC somatic mutation |
PCGP germline mutation [Top] | ||
There is no record for AKR1C2 | ||
PCGP somatic mutation [Top] | ||
There is no record for AKR1C2 | ||
COSMIC somatic mutation [Top] | ||
Mutation (CDS; AA; Chr) | Site | Histology |
|---|---|---|
c.108G>C; p.E36D; |
lung | carcinoma; adenocarcinoma |
c.149_150insA; p.D50fs*8; |
lung | carcinoma; adenocarcinoma |
c.131C>A; p.A44D; |
lung | carcinoma; adenocarcinoma |
c.451A>G; p.M151V; |
lung | carcinoma; adenocarcinoma |
c.229G>A; p.E77K; |
lung | carcinoma; adenocarcinoma |
c.399A>C; p.E133D; |
skin; trunk | malignant_melanoma |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.15C>T; p.Y5Y; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.489C>G; p.I163M; |
lung | carcinoma; adenocarcinoma |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.15C>T; p.Y5Y; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.15C>T; p.Y5Y; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.15C>T; p.Y5Y; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.15C>T; p.Y5Y; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.15C>T; p.Y5Y; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.783G>A; p.L261L; |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV |
c.472G>T; p.G158*; |
lung | carcinoma; squamous_cell_carcinoma |
c.580C>G; p.H194D; |
breast | carcinoma |
c.86T>C; p.V29A; |
large_intestine; colon | carcinoma; adenocarcinoma |
c.46A>G; p.M16V; |
large_intestine; caecum | carcinoma; adenocarcinoma |
c.229G>T; p.E77*; |
large_intestine; rectum | carcinoma; adenocarcinoma |
c.75G>A; p.A25A; |
large_intestine; rectum | carcinoma; adenocarcinoma |
c.75G>A; p.A25A; |
endometrium | carcinoma; endometrioid_carcinoma |
c.127G>T; p.E43*; |
large_intestine; caecum | carcinoma; adenocarcinoma |
c.636T>C; p.V212V; |
endometrium | carcinoma; endometrioid_carcinoma |
c.394G>T; p.D132Y; |
endometrium | carcinoma; endometrioid_carcinoma |
c.628G>T; p.D210Y; |
endometrium | carcinoma; endometrioid_carcinoma |
c.394G>T; p.D132Y; |
endometrium | carcinoma; endometrioid_carcinoma |
c.196C>T; p.R66*; |
breast | carcinoma |
c.362C>T; p.S121F; |
breast | carcinoma |
c.451A>G; p.M151V; |
cervix | carcinoma; squamous_cell_carcinoma |
c.451A>G; p.M151V; |
cervix | carcinoma; squamous_cell_carcinoma |
c.911G>A; p.R304Q; |
breast | carcinoma |