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Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

1646

Name

AKR1C2

Synonym

AKR1C-pseudo|BABP|DD|DD2|DDH2|HAKRD|HBAB|MCDR2|SRXY8;aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III);AKR1C2;aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)

Definition

3-alpha-HSD3|DD-2|DD/BABP|aldo-keto reductase family 1 member C2|chlordecone reductase homolog HAKRD|pseudo-chlordecone reductase|trans-1,2-dihydrobenzene-1,2-diol dehydrogenase|type II dihydrodiol dehydrogenase

Position

10p15-p14

Gene Type

protein-coding

Pathways and Diseases

Pathway

Steroid hormone biosynthesis;KEGG PATHWAY;hsa00140

Pathway

Metabolism of xenobiotics by cytochrome P450;KEGG PATHWAY;hsa00980

Disease

Esophageal disease;FunDO

Disease

Bladder cancer;FunDO

Disease

Barrett's esophagus;FunDO

Disease

Breast cancer;FunDO

Disease

Glaucoma;FunDO

Disease

Obesity, hyperphagia, and developmental delay;OMIM

External Links

Links to Entrez Gene

1646

Links to all GeneRIF Items

1646

Links to iHOP

1646

Sequence Information

Nucleotide Sequence

>1646 : length: 420
atggattcgaaataccagtgtgtgaagctgaatgatggtcacttcatgcctgtcctggga
tttggcacctatgcgcctgcagaggttcctaaaagtaaagctctagaggccgtcaaattg
gcaatagaagccgggttccaccatattgattctgcacatgtttacaataatgaggagcag
gttggactggccatccgaagcaagattgcagatggcagtgtgaagagagaagacatattc
tacacttcaaagctttggagcaattcccatcgaccagagttggtccgaccagccttggaa
aggtcactgaaaaatcttcaattggactatgttgacctctatcttattcattttccagtg
tctgtaaaggaggacatagggattttaacatggaagaagagccctaaacataactcctaa

Protein Sequence

>1646 : length: 139
MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ
VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
SVKEDIGILTWKKSPKHNS



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