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Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

1001

Name

CDH3

Synonymous

CDHP|HJMD|PCAD;cadherin 3, type 1, P-cadherin (placental);CDH3;cadherin 3, type 1, P-cadherin (placental)

Definition

cadherin-3|calcium-dependent adhesion protein, placental

Position

16q22.1

Gene Type

protein-coding

Gene Mutation:

PCGP germline mutation
PCGP somatic mutation
COSMIC somatic mutation

PCGP germline mutation   [Top]

There is no record for CDH3

PCGP somatic mutation   [Top]

Variant (Variant; Chr; Position)

Genotype (MutationType; MutationClass; ReferenceAllele; Genotype; Origin)

Disease (CancerType; ValidationStatus; SequencingType)

CDH3_V698I; chr16; 68729247

 SUB; MISSENSE; G; G/A; SOMATICAMLM7; PUTATIVE-HQ; EXOME

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

c.1118A>G; p.D373G;

haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma

c.1118A>G; p.D373G;

haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma

c.1196A>G; p.E399G;

skin; armmalignant_melanoma

c.619G>A; p.D207N;

livercarcinoma; hepatocellular_carcinoma

c.935C>T; p.A312V;

large_intestine; coloncarcinoma; adenocarcinoma

c.502T>A; p.L168M;

large_intestine; coloncarcinoma; adenocarcinoma

c.853G>T; p.G285C;

lungcarcinoma; small_cell_carcinoma

c.680G>T; p.G227V;

breastcarcinoma; HER-positive_carcinoma

c.444G>A; p.P148P;

oesophaguscarcinoma; adenocarcinoma

c.1093A>G; p.T365A;

lungcarcinoma; adenocarcinoma

c.1201A>T; p.K401*;

lungcarcinoma; adenocarcinoma

c.2469C>T; p.Y823Y;

lungcarcinoma; adenocarcinoma

c.2059C>T; p.L687F;

lungcarcinoma; adenocarcinoma

c.1592C>A; p.T531K;

lungcarcinoma; adenocarcinoma

c.525_526GG>TT; p.R175>?;

lungcarcinoma; adenocarcinoma

c.1541A>G; p.Y514C;

haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemia

c.2213T>C; p.I738T;

NSNS

c.495C>T; p.G165G;

livercarcinoma

c.226C>T; p.R76W;

large_intestine; coloncarcinoma; adenocarcinoma

c.235G>A; p.E79K;

prostateadenoma

c.1237G>A; p.E413K; 16:67276041-67276041

 ovarycarcinoma; serous_carcinoma

c.1984G>A; p.A662T; 16:67283312-67283312

 ovarycarcinoma; serous_carcinoma

c.1756G>T; p.D586Y;

lungcarcinoma; adenocarcinoma

c.2360C>G; p.S787C;

lungcarcinoma; squamous_cell_carcinoma

c.949G>T; p.E317*;

lung; right_upper_lobecarcinoma; adenocarcinoma

c.1116C>T; p.D372D; 16:67273825-67273825

 ovarycarcinoma; serous_carcinoma

c.1504G>A; p.D502N;

lung; right_lower_lobecarcinoma; adenocarcinoma

c.705G>T; p.M235I;

lung; right_upper_lobecarcinoma; adenocarcinoma

c.1182G>T; p.K394N;

large_intestine; caecumcarcinoma; adenocarcinoma

c.2368G>A; p.A790T;

large_intestine; coloncarcinoma; adenocarcinoma

c.1621G>A; p.V541I;

large_intestine; caecumcarcinoma; adenocarcinoma

c.2262C>T; p.I754I;

large_intestine; coloncarcinoma; adenocarcinoma

c.1788C>T; p.N596N;

large_intestine; caecumcarcinoma; adenocarcinoma

c.1339G>A; p.V447I;

large_intestine; rectumcarcinoma; adenocarcinoma

c.31_33delCTC; p.L11delL;

large_intestine; rectumcarcinoma; adenocarcinoma

c.2262C>T; p.I754I;

large_intestine; rectumcarcinoma; adenocarcinoma

c.1403A>G; p.D468G;

endometriumcarcinoma; endometrioid_carcinoma

c.308G>A; p.R103Q;

endometriumcarcinoma; endometrioid_carcinoma

c.1116C>T; p.D372D; 16:67273825-67273825

 endometriumcarcinoma; endometrioid_carcinoma

c.1536C>T; p.N512N;

endometriumcarcinoma; endometrioid_carcinoma

c.431G>A; p.S144N;

endometriumcarcinoma; endometrioid_carcinoma

c.1003G>A; p.A335T;

endometriumcarcinoma; endometrioid_carcinoma

c.1111G>A; p.G371S;

endometriumcarcinoma; endometrioid_carcinoma

c.900C>T; p.A300A;

breastcarcinoma

c.1104C>A; p.I368I;

endometriumcarcinoma; endometrioid_carcinoma

c.1785C>T; p.V595V;

urinary_tract; bladdercarcinoma

c.1364C>T; p.T455I;

urinary_tract; bladdercarcinoma

c.1790A>C; p.E597A;

large_intestine; coloncarcinoma; adenocarcinoma

c.1775C>T; p.T592M;

kidneycarcinoma; clear_cell_renal_cell_carcinoma

c.1290C>T; p.H430H;

endometriumcarcinoma; endometrioid_carcinoma

c.2476G>T; p.G826W;

endometriumcarcinoma; endometrioid_carcinoma

c.1237G>A; p.E413K; 16:67276041-67276041

 large_intestine; coloncarcinoma; adenocarcinoma

c.1114G>A; p.D372N;

large_intestine; coloncarcinoma; adenocarcinoma

c.2395G>A; p.A799T;

breastcarcinoma

c.1115A>G; p.D372G;

large_intestine; coloncarcinoma; adenocarcinoma

c.781G>C; p.E261Q;

urinary_tract; bladdercarcinoma

c.1648C>A; p.P550T;

skinmalignant_melanoma

c.1651C>T; p.R551C;

skinmalignant_melanoma

c.2011C>T; p.L671L;

stomachadenocarcinoma

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