| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 840 |
Name | CASP7 |
Synonymous | CMH-1|ICE-LAP3|MCH3;caspase 7, apoptosis-related cysteine peptidase;CASP7;caspase 7, apoptosis-related cysteine peptidase |
Definition | CASP-7|ICE-like apoptotic protease 3|Lice2 alpha/beta/gamma|apoptotic protease MCH-3|caspase 7 isoform delta|caspase 7, apoptosis-related cysteine protease|caspase-7 |
Position | 10q25 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
BIRC2 | IMID; |
in same component |
BIRC3 | IMID; |
in same component |
BIRC5 | IMID; |
in same component |
DIABLO | REACTOME; |
in same component |
NAIP | IMID; |
in same component |
XIAP | IMID; |
in same component |
XIAP | REACTOME; |
interacts with |
AR | HPRD; |
interacts with |
BIRC2 | BIOGRID; |
interacts with |
BIRC2 | HPRD; |
interacts with |
BIRC3 | BIOGRID; |
interacts with |
BIRC3 | HPRD; |
interacts with |
BIRC5 | BIOGRID; |
interacts with |
BIRC5 | HPRD; |
interacts with |
BIRC7 | BIOGRID; |
interacts with |
BIRC7 | HPRD; |
interacts with |
CASP10 | BIOGRID; |
interacts with |
CASP10 | HPRD; |
interacts with |
CASP2 | BIOGRID; |
interacts with |
CASP8 | BIOGRID; |
interacts with |
CAST | HPRD; |
interacts with |
CDC42 | HPRD; |
interacts with |
CFLAR | HPRD; |
interacts with |
CLSPN | HPRD; |
interacts with |
CTSG | HPRD; |
interacts with |
DCTN1 | HPRD; |
interacts with |
DSP | HPRD; |
interacts with |
EIF2AK2 | HPRD; |
interacts with |
GOLGA3 | HPRD; |
interacts with |
GORASP1 | HPRD; |
interacts with |
HSPA5 | BIOGRID; |
interacts with |
HSPA5 | HPRD; |
interacts with |
KRT18 | HPRD; |
interacts with |
LYN | HPRD; |
interacts with |
MAPT | HPRD; |
interacts with |
MAX | HPRD; |
interacts with |
MEF2A | HPRD; |
interacts with |
MEF2D | HPRD; |
interacts with |
NEDD4 | HPRD; |
interacts with |
NUCB2 | MINT; |
interacts with |
PRKCZ | HPRD; |
interacts with |
PSEN1 | HPRD; |
interacts with |
PSEN2 | HPRD; |
interacts with |
PSIP1 | HPRD; |
interacts with |
PSME3 | HPRD; |
interacts with |
RAC1 | HPRD; |
interacts with |
RAD21 | HPRD; |
interacts with |
RAD51 | HPRD; |
interacts with |
RASA1 | HPRD; |
interacts with |
RB1 | HPRD; |
interacts with |
RNF7 | HPRD; |
interacts with |
SRF | HPRD; |
interacts with |
STK24 | HPRD; |
interacts with |
TNFRSF1A | BIOGRID; |
interacts with |
TNFRSF1A | HPRD; |
interacts with |
UBE4B | HPRD; |
interacts with |
VIM | HPRD; |
interacts with |
XIAP | BIOGRID; |
interacts with |
XIAP | HPRD; |
interacts with |
XIAP | MINT; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
E2F1 | NCI_NATURE; |
metabolic catalysis |
RB1 | NCI_NATURE; |
metabolic catalysis |
TFDP1 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
BIRC2 | IMID; |
reacts with |
BIRC3 | IMID; |
reacts with |
BIRC5 | IMID; |
reacts with |
CASP7 | IMID; |
reacts with |
CASP7 | NCI_NATURE; |
reacts with |
CASP7 | REACTOME; |
reacts with |
DIABLO | REACTOME; |
reacts with |
NAIP | IMID; |
reacts with |
XIAP | IMID; |
reacts with |
XIAP | REACTOME; |
state change |
APAF1 | NCI_NATURE; |
state change |
APAF1 | REACTOME; |
state change |
BIRC3 | NCI_NATURE; |
state change |
CASP2 | NCI_NATURE; |
state change |
CASP8 | NCI_NATURE; |
state change |
CASP9 | IMID; |
state change |
CASP9 | NCI_NATURE; |
state change |
CASP9 | REACTOME; |
state change |
CYCS | REACTOME; |
state change |
GZMB | NCI_NATURE; |