Pediatric cancer gene database (Pedican) Home
Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

840

Name

CASP7

Synonym

CMH-1|ICE-LAP3|MCH3;caspase 7, apoptosis-related cysteine peptidase;CASP7;caspase 7, apoptosis-related cysteine peptidase

Definition

CASP-7|ICE-like apoptotic protease 3|Lice2 alpha/beta/gamma|apoptotic protease MCH-3|caspase 7 isoform delta|caspase 7, apoptosis-related cysteine protease|caspase-7

Position

10q25

Gene Type

protein-coding

Pathways and Diseases

Pathway

Apoptosis;Reactome;REACT:578

Pathway

E2F transcription factor network;PID Curated;200027

Pathway

apoptotic signaling in response to dna damage;PID BioCarta;100204

Pathway

Apoptosis;KEGG PATHWAY;hsa04210

Pathway

fas signaling pathway (cd95);PID BioCarta;100167

Pathway

Caspase cascade in apoptosis;PID Curated;200148

Pathway

b cell survival pathway;PID BioCarta;100228

Pathway

Apoptotic cleavage of cellular proteins;PID Reactome;500270

Pathway

hiv-1 nef: negative effector of fas and tnf;PID BioCarta;100144

Pathway

induction of apoptosis through dr3 and dr4/5 death receptors;PID BioCarta;100189

Pathway

HIV-1 Nef: Negative effector of Fas and TNF-alpha;PID Curated;200133

Pathway

Apoptosis signaling pathway;PANTHER;P00006

Pathway

caspase cascade in apoptosis;PID BioCarta;100218

Pathway

Alzheimer's disease;KEGG PATHWAY;hsa05010

Pathway

apoptotic dna-fragmentation and tissue homeostasis;PID BioCarta;100187

Pathway

west nile virus;PID BioCarta;100001

Pathway

Activation of caspases through apoptosome-mediated cleavage;PID Reactome;500267

Pathway

FAS signaling pathway;PANTHER;P00020

Pathway

trefoil factors initiate mucosal healing;PID BioCarta;100018

Pathway

regulation of cell cycle progression by plk3;PID BioCarta;100068

Disease

diabetes, type 1;GAD

Disease

CHEMDEPENDENCY;GAD

Disease

IMMUNE;GAD

Disease

smoking cessation;GAD

Disease

Lymphoma;FunDO

Disease

Periodontitis;FunDO

Disease

Melanoma;FunDO

Disease

Stomach cancer;FunDO

External Links

Links to Entrez Gene

840

Links to all GeneRIF Items

840

Links to iHOP

840

Sequence Information

Nucleotide Sequence

>840 : length: 912
atggcagatgatcagggctgtattgaagagcagggggttgaggattcagcaaatgaagat
tcagtggatgctaagccagaccggtcctcgtttgtaccgtccctcttcagtaagaagaag
aaaaatgtcaccatgcgatccatcaagaccacccgggaccgagtgcctacatatcagtac
aacatgaattttgaaaagctgggcaaatgcatcataataaacaacaagaactttgataaa
gtgacaggtatgggcgttcgaaacggaacagacaaagatgccgaggcgctcttcaagtgc
ttccgaagcctgggttttgacgtgattgtctataatgactgctcttgtgccaagatgcaa
gatctgcttaaaaaagcttctgaagaggaccatacaaatgccgcctgcttcgcctgcatc
ctcttaagccatggagaagaaaatgtaatttatgggaaagatggtgtcacaccaataaag
gatttgacagcccactttaggggggatagatgcaaaacccttttagagaaacccaaactc
ttcttcattcaggcttgccgagggaccgagcttgatgatggcatccaggccgactcgggg
cccatcaatgacacagatgctaatcctcgatacaagatcccagtggaagctgacttcctc
ttcgcctattccacggttccaggctattactcgtggaggagcccaggaagaggctcctgg
tttgtgcaagccctctgctccatcctggaggagcacggaaaagacctggaaatcatgcag
atcctcaccagggtgaatgacagagttgccaggcactttgagtctcagtctgatgaccca
cacttccatgagaagaagcagatcccctgtgtggtctccatgctcaccaaggaactctac
ttcagtcaatag

Protein Sequence

>840 : length: 303
MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
FSQ



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