| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 5578 |
Name | PRKCA |
Synonymous | AAG6|PKC-alpha|PKCA|PRKACA;protein kinase C, alpha;PRKCA;protein kinase C, alpha |
Definition | PKC-A|aging-associated gene 6|protein kinase C alpha type |
Position | 17q22-q23.2 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
AKAP5 | IMID; |
in same component |
ARHGAP1 | IMID; |
in same component |
CHUK | NCI_NATURE; |
in same component |
DNM1 | IMID; |
in same component |
GDNF | NCI_NATURE; |
in same component |
GFRA1 | NCI_NATURE; |
in same component |
Gnb2l1 | IMID; |
in same component |
IKBKB | NCI_NATURE; |
in same component |
IKBKG | NCI_NATURE; |
in same component |
KIT | REACTOME; |
in same component |
SDC4 | NCI_NATURE; |
interacts with |
ACTA1 | HPRD; |
interacts with |
ADAM12 | NCI_NATURE; |
interacts with |
ADAP1 | HPRD; |
interacts with |
ADCY5 | HPRD; |
interacts with |
ADD3 | HPRD; |
interacts with |
ADRA1B | HPRD; |
interacts with |
ADRBK1 | HPRD; |
interacts with |
AFAP1 | BIOGRID; |
interacts with |
AFAP1 | HPRD; |
interacts with |
AKAP12 | BIOGRID; |
interacts with |
AKAP12 | HPRD; |
interacts with |
ANXA2 | HPRD; |
interacts with |
APLP2 | HPRD; |
interacts with |
ARHGEF1 | HPRD; |
interacts with |
ATP1A1 | BIOGRID; |
interacts with |
ATP2B1 | HPRD; |
interacts with |
ATP2B2 | HPRD; |
interacts with |
AVPR1A | BIOGRID; |
interacts with |
AVPR1A | HPRD; |
interacts with |
AVPR1B | BIOGRID; |
interacts with |
AVPR2 | BIOGRID; |
interacts with |
BCL2 | HPRD; |
interacts with |
BTG2 | HPRD; |
interacts with |
BTK | HPRD; |
interacts with |
C1QBP | BIOGRID; |
interacts with |
C1QBP | HPRD; |
interacts with |
CASR | HPRD; |
interacts with |
CBL | HPRD; |
interacts with |
CD163 | HPRD; |
interacts with |
CD53 | BIOGRID; |
interacts with |
CD5 | HPRD; |
interacts with |
CD9 | BIOGRID; |
interacts with |
CD9 | HPRD; |
interacts with |
CDC42 | HPRD; |
interacts with |
CFTR | HPRD; |
interacts with |
CHAT | HPRD; |
interacts with |
CHUK | BIOGRID; |
interacts with |
CISH | HPRD; |
interacts with |
CORO1B | HPRD; |
interacts with |
CYTH2 | HPRD; |
interacts with |
DDX5 | HPRD; |
interacts with |
DGKD | HPRD; |
interacts with |
DGKZ | HPRD; |
interacts with |
DLG4 | BIOGRID; |
interacts with |
DLG4 | HPRD; |
interacts with |
DLX3 | HPRD; |
interacts with |
DNM1 | HPRD; |
interacts with |
DVL2 | CELL_MAP; |
interacts with |
DVL2 | HPRD; |
interacts with |
EDF1 | HPRD; |
interacts with |
EEF1D | HPRD; |
interacts with |
EGFR | BIOGRID; |
interacts with |
EGFR | CELL_MAP; |
interacts with |
EGFR | HPRD; |
interacts with |
EIF2S1 | MINT; |
interacts with |
EIF4E | HPRD; |
interacts with |
ENTPD5 | HPRD; |
interacts with |
EZR | BIOGRID; |
interacts with |
EZR | HPRD; |
interacts with |
F11R | HPRD; |
interacts with |
FLNA | HPRD; |
interacts with |
FLNC | HPRD; |
interacts with |
FSCN1 | BIOGRID; |
interacts with |
FSCN1 | HPRD; |
interacts with |
GABRB3 | BIOGRID; |
interacts with |
GABRG2 | HPRD; |
interacts with |
GABRR1 | HPRD; |
interacts with |
GABRR2 | HPRD; |
interacts with |
GFAP | HPRD; |
interacts with |
GFPT1 | HPRD; |
interacts with |
GIPC1 | MINT; |
interacts with |
GJA1 | BIOGRID; |
interacts with |
GJA1 | HPRD; |
interacts with |
GJB1 | HPRD; |
interacts with |
GMFB | HPRD; |
interacts with |
GNA15 | HPRD; |
interacts with |
GPM6A | HPRD; |
interacts with |
GRIA2 | HPRD; |
interacts with |
GRIA4 | HPRD; |
interacts with |
GRIN2B | HPRD; |
interacts with |
GRM1 | HPRD; |
interacts with |
GRM5 | HPRD; |
interacts with |
GRM7 | BIOGRID; |
interacts with |
GSK3A | HPRD; |
interacts with |
GSK3B | BIOGRID; |
interacts with |
HABP4 | BIOGRID; |
interacts with |
HABP4 | HPRD; |
interacts with |
HAND1 | BIOGRID; |
interacts with |
HAND1 | HPRD; |
interacts with |
HES1 | HPRD; |
interacts with |
HLA-A | HPRD; |
interacts with |
HMGA1 | BIOGRID; |
interacts with |
HMGA2 | BIOGRID; |
interacts with |
HMGB1 | HPRD; |
interacts with |
HMGN1 | HPRD; |
interacts with |
HMGN2 | HPRD; |
interacts with |
HSP90AA1 | HPRD; |
interacts with |
HSPB8 | HPRD; |
interacts with |
IKBKB | BIOGRID; |
interacts with |
INADL | MINT; |
interacts with |
INSR | HPRD; |
interacts with |
ITGB1 | BIOGRID; |
interacts with |
ITGB1 | HPRD; |
interacts with |
ITGB2 | HPRD; |
interacts with |
ITGB4 | HPRD; |
interacts with |
ITPKA | HPRD; |
interacts with |
ITPKB | HPRD; |
interacts with |
JAK1 | MINT; |
interacts with |
Jak2 | MINT; |
interacts with |
KCNE4 | HPRD; |
interacts with |
KCNQ2 | HPRD; |
interacts with |
KIT | HPRD; |
interacts with |
KLF5 | BIOGRID; |
interacts with |
KRT18 | HPRD; |
interacts with |
LCK | HPRD; |
interacts with |
LMNA | BIOGRID; |
interacts with |
LMNA | HPRD; |
interacts with |
LMNB1 | BIOGRID; |
interacts with |
LMNB1 | HPRD; |
interacts with |
MARCKS | HPRD; |
interacts with |
MBP | HPRD; |
interacts with |
MYLK | HPRD; |
interacts with |
MYOD1 | HPRD; |
interacts with |
NCF1 | HPRD; |
interacts with |
NCF1 | MINT; |
interacts with |
NFATC1 | HPRD; |
interacts with |
NOS1 | HPRD; |
interacts with |
NRGN | HPRD; |
interacts with |
NUMB | HPRD; |
interacts with |
OCLN | HPRD; |
interacts with |
OGG1 | BIOGRID; |
interacts with |
OGG1 | HPRD; |
interacts with |
OPRD1 | HPRD; |
interacts with |
PA2G4 | HPRD; |
interacts with |
PAM | HPRD; |
interacts with |
PDLIM7 | HPRD; |
interacts with |
PEA15 | HPRD; |
interacts with |
PEBP1 | HPRD; |
interacts with |
PFKFB2 | HPRD; |
interacts with |
PICK1 | BIOGRID; |
interacts with |
PICK1 | HPRD; |
interacts with |
PLCB1 | HPRD; |
interacts with |
PLCG2 | HPRD; |
interacts with |
PLD1 | BIOGRID; |
interacts with |
PLD2 | BIOGRID; |
interacts with |
PLD2 | CELL_MAP; |
interacts with |
PLD2 | HPRD; |
interacts with |
POLB | HPRD; |
interacts with |
PPARA | HPRD; |
interacts with |
PPP1R14A | HPRD; |
interacts with |
PRKCE | MINT; |
interacts with |
PRKCZ | HPRD; |
interacts with |
PRKG1 | HPRD; |
interacts with |
PTGIR | HPRD; |
interacts with |
PTPN11 | HPRD; |
interacts with |
PTPN12 | HPRD; |
interacts with |
PTPN6 | HPRD; |
interacts with |
RAC1 | HPRD; |
interacts with |
RAC1 | MINT; |
interacts with |
RAF1 | HPRD; |
interacts with |
RALBP1 | HPRD; |
interacts with |
RALBP1 | MINT; |
interacts with |
RGS19 | HPRD; |
interacts with |
RGS2 | BIOGRID; |
interacts with |
RGS2 | HPRD; |
interacts with |
RGS7 | HPRD; |
interacts with |
RHOA | HPRD; |
interacts with |
RHOA | NCI_NATURE; |
interacts with |
RHO | HPRD; |
interacts with |
RICTOR | MINT; |
interacts with |
RPL10 | HPRD; |
interacts with |
RPS6KA2 | MINT; |
interacts with |
RRAD | HPRD; |
interacts with |
SCTR | HPRD; |
interacts with |
SDC2 | HPRD; |
interacts with |
SDC4 | HPRD; |
interacts with |
SDC4 | NCI_NATURE; |
interacts with |
SDPR | HPRD; |
interacts with |
SEMG1 | HPRD; |
interacts with |
SEMG2 | HPRD; |
interacts with |
SHC1 | HPRD; |
interacts with |
SLC1A1 | BIOGRID; |
interacts with |
SLC1A1 | HPRD; |
interacts with |
SLC6A9 | HPRD; |
interacts with |
SNAP23 | HPRD; |
interacts with |
SPP1 | HPRD; |
interacts with |
SRC | HPRD; |
interacts with |
STXBP3 | HPRD; |
interacts with |
SYK | HPRD; |
interacts with |
TEP1 | HPRD; |
interacts with |
TERT | HPRD; |
interacts with |
THOC5 | HPRD; |
interacts with |
TIAM1 | BIOGRID; |
interacts with |
TIAM1 | HPRD; |
interacts with |
TNNI3 | HPRD; |
interacts with |
TNNT2 | HPRD; |
interacts with |
TNP1 | BIOGRID; |
interacts with |
TNP2 | BIOGRID; |
interacts with |
TOP2A | HPRD; |
interacts with |
TRIM29 | HPRD; |
interacts with |
TRIM41 | BIOGRID; |
interacts with |
TRPC3 | HPRD; |
interacts with |
TRPV6 | HPRD; |
interacts with |
TYK2 | MINT; |
interacts with |
VCL | HPRD; |
interacts with |
VTN | HPRD; |
interacts with |
XK | HPRD; |
interacts with |
YWHAG | BIOGRID; |
interacts with |
YWHAG | HPRD; |
interacts with |
YWHAZ | BIOGRID; |
interacts with |
YWHAZ | HPRD; |
Metabolic Interaction [Top] | ||
There is no record for PRKCA | ||
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
AKAP5 | IMID; |
reacts with |
ARHGAP1 | IMID; |
reacts with |
CHUK | NCI_NATURE; |
reacts with |
DNM1 | IMID; |
reacts with |
GDNF | NCI_NATURE; |
reacts with |
GFRA1 | NCI_NATURE; |
reacts with |
Gnb2l1 | IMID; |
reacts with |
IKBKB | NCI_NATURE; |
reacts with |
IKBKG | NCI_NATURE; |
reacts with |
KIT | REACTOME; |
reacts with |
PRKCA | IMID; |
reacts with |
PRKCA | NCI_NATURE; |
reacts with |
PRKCA | REACTOME; |
reacts with |
SDC4 | NCI_NATURE; |
state change |
MAPKAP1 | NCI_NATURE; |
state change |
MLST8 | NCI_NATURE; |
state change |
MTOR | NCI_NATURE; |
state change |
PDPK1 | IMID; |
state change |
PRKCA | REACTOME; |
state change |
RICTOR | NCI_NATURE; |
state change |
SDC4 | NCI_NATURE; |