Entrez Gene

Pediatric cancer gene database (Pedican) Home

General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information
Gene ID	4893
Name	NRAS
Synonymous	ALPS4\|N-ras\|NRAS1\|NS6;neuroblastoma RAS viral (v-ras) oncogene homolog;NRAS;neuroblastoma RAS viral (v-ras) oncogene homolog
Definition	GTPase NRas\|N-ras protein part 4\|transforming protein N-Ras\|v-ras neuroblastoma RAS viral oncogene homolog
Position	1p13.2
Gene Type	protein-coding
Gene Interactions:	Physical Interaction Metabolic Interaction Signaling Interaction

Interaction Type	Interactor	Data Source
Physical Interaction [Top]
in same component	CALM1	IMID;
in same component	NF1	IMID;
in same component	PIK3CA	IMID;
in same component	RAF1	IMID;
in same component	RALGDS	IMID;
in same component	RAP2A	IMID;
in same component	RIN1	IMID;
interacts with	ACVR1	HPRD;
interacts with	ARHGAP4	HPRD;
interacts with	BCL2	HPRD;
interacts with	MLLT4	BIOGRID;
interacts with	PIK3CA	HPRD;
interacts with	PIK3CG	BIOGRID;
interacts with	PLCE1	BIOGRID;
interacts with	PLCE1	HPRD;
interacts with	PLCE1	MINT;
interacts with	RACGAP1	HPRD;
interacts with	RAF1	BIOGRID;
interacts with	RAF1	HPRD;
interacts with	RAP1GDS1	BIOGRID;
interacts with	RASGRP2	HPRD;
interacts with	RASSF5	HPRD;
interacts with	SHOC2	CELL_MAP;
interacts with	SHOC2	HPRD;
interacts with	SMAD4	HPRD;
interacts with	SMURF2	HPRD;

Interaction Type	Interactor	Data Source
Metabolic Interaction [Top]
metabolic catalysis	MYB	NCI_NATURE;

Interaction Type	Interactor	Data Source
Signaling Interaction [Top]
reacts with	CALM1	IMID;
reacts with	NF1	IMID;
reacts with	NRAS	IMID;
reacts with	PIK3CA	IMID;
reacts with	RAF1	IMID;
reacts with	RALGDS	IMID;
reacts with	RAP2A	IMID;
reacts with	RIN1	IMID;
state change	IQGAP1	IMID;
state change	RAPGEF1	IMID;
state change	RASA4	IMID;
state change	RASGRF1	IMID;
state change	RASGRP3	IMID;
state change	SOS1	IMID;
state change	SYNGAP1	IMID;

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