| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 4893 |
Name | NRAS |
Synonym | ALPS4|N-ras|NRAS1|NS6;neuroblastoma RAS viral (v-ras) oncogene homolog;NRAS;neuroblastoma RAS viral (v-ras) oncogene homolog |
Definition | GTPase NRas|N-ras protein part 4|transforming protein N-Ras|v-ras neuroblastoma RAS viral oncogene homolog |
Position | 1p13.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | B cell receptor signaling pathway;KEGG PATHWAY;hsa04662 |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
Pathway | Signaling by Insulin receptor;Reactome;REACT:498 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | Endometrial cancer;KEGG PATHWAY;hsa05213 |
Pathway | TGF-beta signaling pathway;PANTHER;P00052 |
Pathway | FGF signaling pathway;PANTHER;P00021 |
Pathway | VEGF signaling pathway;KEGG PATHWAY;hsa04370 |
Pathway | Melanogenesis;KEGG PATHWAY;hsa04916 |
Pathway | Signaling by EGFR;Reactome;REACT:9417 |
Pathway | T cell activation;PANTHER;P00053 |
Pathway | Chronic myeloid leukemia;KEGG PATHWAY;hsa05220 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | T cell receptor signaling pathway;KEGG PATHWAY;hsa04660 |
Pathway | PDGF signaling pathway;PANTHER;P00047 |
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | Bladder cancer;KEGG PATHWAY;hsa05219 |
Pathway | Hepatitis C;KEGG PATHWAY;hsa05160 |
Pathway | PI3 kinase pathway;PANTHER;P00048 |
Pathway | EGF receptor signaling pathway;PANTHER;P00018 |
Pathway | Insulin signaling pathway;KEGG PATHWAY;hsa04910 |
Pathway | ErbB signaling pathway;KEGG PATHWAY;hsa04012 |
Pathway | Signaling by PDGF;Reactome;REACT:16888 |
Pathway | VEGF signaling pathway;PANTHER;P00056 |
Pathway | B cell activation;PANTHER;P00010 |
Pathway | Long-term potentiation;KEGG PATHWAY;hsa04720 |
Pathway | Fc epsilon RI signaling pathway;KEGG PATHWAY;hsa04664 |
Pathway | Prostate cancer;KEGG PATHWAY;hsa05215 |
Pathway | Non-small cell lung cancer;KEGG PATHWAY;hsa05223 |
Pathway | Angiogenesis;PANTHER;P00005 |
Pathway | Integrin signalling pathway;PANTHER;P00034 |
Pathway | GnRH signaling pathway;KEGG PATHWAY;hsa04912 |
Pathway | Renal cell carcinoma;KEGG PATHWAY;hsa05211 |
Pathway | Thyroid cancer;KEGG PATHWAY;hsa05216 |
Pathway | Melanoma;KEGG PATHWAY;hsa05218 |
Pathway | Glioma;KEGG PATHWAY;hsa05214 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | Gap junction;KEGG PATHWAY;hsa04540 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Chemokine signaling pathway;KEGG PATHWAY;hsa04062 |
Pathway | Tight junction;KEGG PATHWAY;hsa04530 |
Pathway | Long-term depression;KEGG PATHWAY;hsa04730 |
Pathway | p53 pathway feedback loops 2;PANTHER;P04398 |
Pathway | Interleukin signaling pathway;PANTHER;P00036 |
Pathway | C-MYB transcription factor network;PID Curated;200130 |
Pathway | Ras Pathway;PANTHER;P04393 |
Pathway | Natural killer cell mediated cytotoxicity;KEGG PATHWAY;hsa04650 |
Pathway | Acute myeloid leukemia;KEGG PATHWAY;hsa05221 |
Disease | Thyroid cancer;KEGG DISEASE;H00032 |
Disease | leukemia, myeloid;GAD |
Disease | Adrenal carcinoma;KEGG DISEASE;H00033 |
Disease | Colorectal cancer;OMIM |
Disease | Autoimmune lymphoproliferative syndrome type IV;OMIM |
Disease | Multiple myeloma;KEGG DISEASE;H00010 |
Disease | Skin cancers;KEGG DISEASE |
Disease | Cancers of haematopoietic and lymphoid tissues;KEGG DISEASE |
Disease | Cancers of endocrine organs;KEGG DISEASE |
Disease | Thyroid carcinoma, follicular;OMIM |
Disease | Cancers of the digestive system;KEGG DISEASE |
Disease | Autoimmune lymphoproliferative syndromes;KEGG DISEASE;H00108 |
Disease | Hepatocellular carcinoma;KEGG DISEASE;H00048 |
Disease | CANCER;GAD |
Disease | Oral cancer;KEGG DISEASE;H00016 |
Disease | melanoma;GAD |
Disease | Noonan syndrome 6;OMIM |
Disease | Primary immunodeficiency;KEGG DISEASE |
Disease | Cancers;KEGG DISEASE |
Disease | Acute myeloid leukemia (AML);KEGG DISEASE;H00003 |
Disease | Malignant melanoma;KEGG DISEASE;H00038 |
Disease | Immune system diseases;KEGG DISEASE |
Disease | clonal homozygosity of rectal cell carcinoma;GAD |
Disease | Head and neck cancers;KEGG DISEASE |
External Links | |
Links to Entrez Gene | 4893 |
Links to all GeneRIF Items | 4893 |
Links to iHOP | 4893 |
Sequence Information | |
Nucleotide Sequence | >4893 : length: 570 atgactgagtacaaactggtggtggttggagcaggtggtgttgggaaaagcgcactgaca atccagctaatccagaaccactttgtagatgaatatgatcccaccatagaggattcttac agaaaacaagtggttatagatggtgaaacctgtttgttggacatactggatacagctgga caagaagagtacagtgccatgagagaccaatacatgaggacaggcgaaggcttcctctgt gtatttgccatcaataatagcaagtcatttgcggatattaacctctacagggagcagatt aagcgagtaaaagactcggatgatgtacctatggtgctagtgggaaacaagtgtgatttg ccaacaaggacagttgatacaaaacaagcccacgaactggccaagagttacgggattcca ttcattgaaacctcagccaagaccagacagggtgttgaagatgctttttacacactggta agagaaatacgccagtaccgaatgaaaaaactcaacagcagtgatgatgggactcagggt tgtatgggattgccatgtgtggtgatgtaa |
Protein Sequence | >4893 : length: 189 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQG CMGLPCVVM |