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Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

4751

Name

NEK2

Synonymous

HsPK21|NEK2A|NLK1;NIMA (never in mitosis gene a)-related kinase 2;NEK2;NIMA (never in mitosis gene a)-related kinase 2

Definition

nimA-like protein kinase 1|nimA-related protein kinase 2|serine/threonine-protein kinase Nek2

Position

1q32.2-q41

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 ACTR1AREACTOME;

in same component

 AKAP9REACTOME;

in same component

 ALMS1REACTOME;

in same component

 ANAPC10REACTOME;

in same component

 ANAPC11REACTOME;

in same component

 ANAPC1REACTOME;

in same component

 ANAPC2REACTOME;

in same component

 ANAPC4REACTOME;

in same component

 ANAPC5REACTOME;

in same component

 ANAPC7REACTOME;

in same component

 AZI1REACTOME;

in same component

 BUB1BREACTOME;

in same component

 BUB3REACTOME;

in same component

 CCP110REACTOME;

in same component

 CDC16REACTOME;

in same component

 CDC20REACTOME;

in same component

 CDC23REACTOME;

in same component

 CDC26REACTOME;

in same component

 CDC27REACTOME;

in same component

 CDK1REACTOME;

in same component

 CDK5RAP2REACTOME;

in same component

 CENPJREACTOME;

in same component

 CEP135REACTOME;

in same component

 CEP152REACTOME;

in same component

 CEP164REACTOME;

in same component

 CEP192REACTOME;

in same component

 CEP250REACTOME;

in same component

 CEP290REACTOME;

in same component

 CEP57REACTOME;

in same component

 CEP63REACTOME;

in same component

 CEP70REACTOME;

in same component

 CEP72REACTOME;

in same component

 CEP76REACTOME;

in same component

 CEP78REACTOME;

in same component

 CETN2REACTOME;

in same component

 CKAP5REACTOME;

in same component

 CLASP1REACTOME;

in same component

 CNTRLREACTOME;

in same component

 CSNK1DREACTOME;

in same component

 CSNK1EREACTOME;

in same component

 DCTN2REACTOME;

in same component

 DCTN3REACTOME;

in same component

 DYNC1H1REACTOME;

in same component

 DYNC1I2REACTOME;

in same component

 DYNLL1REACTOME;

in same component

 FGFR1OPREACTOME;

in same component

 HAUS2REACTOME;

in same component

 HSP90AA1REACTOME;

in same component

 MAD2L1REACTOME;

in same component

 MAPRE1REACTOME;

in same component

 NDE1REACTOME;

in same component

 NEDD1REACTOME;

in same component

 NINLREACTOME;

in same component

 ODF2REACTOME;

in same component

 OFD1REACTOME;

in same component

 PAFAH1B1REACTOME;

in same component

 PCM1REACTOME;

in same component

 PCNTREACTOME;

in same component

 PLK1REACTOME;

in same component

 PLK4REACTOME;

in same component

 PPP2R1AREACTOME;

in same component

 PRKACAREACTOME;

in same component

 PRKAR2BREACTOME;

in same component

 SDCCAG8REACTOME;

in same component

 SFI1REACTOME;

in same component

 SSNA1REACTOME;

in same component

 TSGA14REACTOME;

in same component

 TUBA1AREACTOME;

in same component

 TUBA4AREACTOME;

in same component

 TUBB2CREACTOME;

in same component

 TUBB4REACTOME;

in same component

 TUBBREACTOME;

in same component

 TUBG1REACTOME;

in same component

 TUBG2REACTOME;

in same component

 TUBGCP2REACTOME;

in same component

 TUBGCP3REACTOME;

in same component

 TUBGCP4REACTOME;

in same component

 TUBGCP5REACTOME;

in same component

 TUBGCP6REACTOME;

in same component

 UBE2CREACTOME;

in same component

 UBE2D1REACTOME;

in same component

 UBE2E1REACTOME;

in same component

 YWHAEREACTOME;

in same component

 YWHAGREACTOME;

interacts with

 CEP250BIOGRID;

interacts with

 CEP250HPRD;

interacts with

 CLEC4CBIOGRID;

interacts with

 MAD1L1HPRD;

interacts with

 MAPK1BIOGRID;

interacts with

 MAPK1HPRD;

interacts with

 NDC80BIOGRID;

interacts with

 NEK11HPRD;

interacts with

 PPP1CAHPRD;

interacts with

 PPP1R2BIOGRID;

interacts with

 PPP1R2HPRD;

interacts with

 TID3BIOGRID;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 FOXM1NCI_NATURE;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 ACTR1AREACTOME;

reacts with

 AKAP9REACTOME;

reacts with

 ALMS1REACTOME;

reacts with

 ANAPC10REACTOME;

reacts with

 ANAPC11REACTOME;

reacts with

 ANAPC1REACTOME;

reacts with

 ANAPC2REACTOME;

reacts with

 ANAPC4REACTOME;

reacts with

 ANAPC5REACTOME;

reacts with

 ANAPC7REACTOME;

reacts with

 AZI1REACTOME;

reacts with

 BUB1BREACTOME;

reacts with

 BUB3REACTOME;

reacts with

 CCP110REACTOME;

reacts with

 CDC16REACTOME;

reacts with

 CDC20REACTOME;

reacts with

 CDC23REACTOME;

reacts with

 CDC26REACTOME;

reacts with

 CDC27REACTOME;

reacts with

 CDK1REACTOME;

reacts with

 CDK5RAP2REACTOME;

reacts with

 CENPJREACTOME;

reacts with

 CEP135REACTOME;

reacts with

 CEP152REACTOME;

reacts with

 CEP164REACTOME;

reacts with

 CEP192REACTOME;

reacts with

 CEP250REACTOME;

reacts with

 CEP290REACTOME;

reacts with

 CEP57REACTOME;

reacts with

 CEP63REACTOME;

reacts with

 CEP70REACTOME;

reacts with

 CEP72REACTOME;

reacts with

 CEP76REACTOME;

reacts with

 CEP78REACTOME;

reacts with

 CETN2REACTOME;

reacts with

 CKAP5REACTOME;

reacts with

 CLASP1REACTOME;

reacts with

 CNTRLREACTOME;

reacts with

 CSNK1DREACTOME;

reacts with

 CSNK1EREACTOME;

reacts with

 DCTN2REACTOME;

reacts with

 DCTN3REACTOME;

reacts with

 DYNC1H1REACTOME;

reacts with

 DYNC1I2REACTOME;

reacts with

 DYNLL1REACTOME;

reacts with

 FGFR1OPREACTOME;

reacts with

 HAUS2REACTOME;

reacts with

 HSP90AA1REACTOME;

reacts with

 MAD2L1REACTOME;

reacts with

 MAPRE1REACTOME;

reacts with

 NDE1REACTOME;

reacts with

 NEDD1REACTOME;

reacts with

 NEK2REACTOME;

reacts with

 NINLREACTOME;

reacts with

 ODF2REACTOME;

reacts with

 OFD1REACTOME;

reacts with

 PAFAH1B1REACTOME;

reacts with

 PCM1REACTOME;

reacts with

 PCNTREACTOME;

reacts with

 PLK1REACTOME;

reacts with

 PLK4REACTOME;

reacts with

 PPP2R1AREACTOME;

reacts with

 PRKACAREACTOME;

reacts with

 PRKAR2BREACTOME;

reacts with

 SDCCAG8REACTOME;

reacts with

 SFI1REACTOME;

reacts with

 SSNA1REACTOME;

reacts with

 TSGA14REACTOME;

reacts with

 TUBA1AREACTOME;

reacts with

 TUBA4AREACTOME;

reacts with

 TUBB2CREACTOME;

reacts with

 TUBB4REACTOME;

reacts with

 TUBBREACTOME;

reacts with

 TUBG1REACTOME;

reacts with

 TUBG2REACTOME;

reacts with

 TUBGCP2REACTOME;

reacts with

 TUBGCP3REACTOME;

reacts with

 TUBGCP4REACTOME;

reacts with

 TUBGCP5REACTOME;

reacts with

 TUBGCP6REACTOME;

reacts with

 UBE2CREACTOME;

reacts with

 UBE2D1REACTOME;

reacts with

 UBE2E1REACTOME;

reacts with

 YWHAEREACTOME;

reacts with

 YWHAGREACTOME;

state change

 ANAPC10REACTOME;

state change

 ANAPC11REACTOME;

state change

 ANAPC1REACTOME;

state change

 ANAPC2REACTOME;

state change

 ANAPC4REACTOME;

state change

 ANAPC5REACTOME;

state change

 ANAPC7REACTOME;

state change

 BUB1BREACTOME;

state change

 BUB3REACTOME;

state change

 CDC16REACTOME;

state change

 CDC20REACTOME;

state change

 CDC23REACTOME;

state change

 CDC26REACTOME;

state change

 CDC27REACTOME;

state change

 MAD2L1REACTOME;

state change

 NEK2REACTOME;

state change

 PLK1REACTOME;

state change

 UBE2CREACTOME;

state change

 UBE2D1REACTOME;

state change

 UBE2E1REACTOME;

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