| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 4286 |
Name | MITF |
Synonymous | MI|WS2|WS2A|bHLHe32;microphthalmia-associated transcription factor;MITF;microphthalmia-associated transcription factor |
Definition | class E basic helix-loop-helix protein 32 |
Position | 3p14.2-p14.1 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
LEF1 | IMID; |
in same component |
PIAS3 | NCI_NATURE; |
interacts with |
FOS | BIOGRID; |
interacts with |
LEF1 | BIOGRID; |
interacts with |
PATZ1 | BIOGRID; |
interacts with |
PAX6 | BIOGRID; |
interacts with |
PIAS1 | BIOGRID; |
interacts with |
PIAS2 | BIOGRID; |
interacts with |
PIAS3 | BIOGRID; |
interacts with |
SPI1 | BIOGRID; |
interacts with |
TFE3 | BIOGRID; |
interacts with |
TFEC | BIOGRID; |
interacts with |
UBE2I | BIOGRID; |
interacts with |
YWHAZ | MINT; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
CTNNB1 | NCI_NATURE; |
metabolic catalysis |
LEF1 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
LEF1 | IMID; |
reacts with |
MITF | IMID; |
reacts with |
MITF | NCI_NATURE; |
reacts with |
PIAS3 | NCI_NATURE; |
reacts with |
RPS6KB1 | NCI_NATURE; |
reacts with |
STAT3 | NCI_NATURE; |
state change |
GSK3A | IMID; |
state change |
IL6 | NCI_NATURE; |
state change |
IL6R | NCI_NATURE; |
state change |
IL6ST | NCI_NATURE; |
state change |
JAK1 | NCI_NATURE; |