| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 3123 |
Name | HLA-DRB1 |
Synonymous | DRB1|DRw10|HLA-DR1B|HLA-DRB|SS1;major histocompatibility complex, class II, DR beta 1;HLA-DRB1;major histocompatibility complex, class II, DR beta 1 |
Definition | DW2.2/DR2.2|HLA class II histocompatibility antigen, DR-1 beta chain|MHC class II HLA-DR beta 1 chain|MHC class II HLA-DR-beta cell surface glycoprotein|MHC class II HLA-DRw10-beta|MHC class II antigen|human leucocyte antigen DRB1|lymphocyte antigen DRB1 |
Position | 6p21.3 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
CBL | NCI_NATURE; |
in same component |
CD247 | NCI_NATURE; |
in same component |
CD3D | NCI_NATURE; |
in same component |
CD3E | NCI_NATURE; |
in same component |
CD3G | NCI_NATURE; |
in same component |
CD4 | NCI_NATURE; |
in same component |
FYN | NCI_NATURE; |
in same component |
HLA-DRA | NCI_NATURE; |
in same component |
LCK | NCI_NATURE; |
in same component |
SH3BP2 | NCI_NATURE; |
in same component |
SLA2 | NCI_NATURE; |
in same component |
ZAP70 | NCI_NATURE; |
interacts with |
CD1D | HPRD; |
interacts with |
CD38 | HPRD; |
interacts with |
CD74 | HPRD; |
interacts with |
CD74 | INTACT; |
interacts with |
CTAG1A | HPRD; |
interacts with |
HLA-DMA | INTACT; |
interacts with |
HLA-DMB | INTACT; |
interacts with |
HLA-DRA | HPRD; |
interacts with |
HLA-DRA | INTACT; |
interacts with |
HLA-DRA | MINT; |
interacts with |
MBP | HPRD; |
interacts with |
MBP | INTACT; |
Metabolic Interaction [Top] | ||
There is no record for HLA-DRB1 | ||
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
CBL | NCI_NATURE; |
reacts with |
CD247 | NCI_NATURE; |
reacts with |
CD3D | NCI_NATURE; |
reacts with |
CD3E | NCI_NATURE; |
reacts with |
CD3G | NCI_NATURE; |
reacts with |
CD4 | NCI_NATURE; |
reacts with |
FYN | NCI_NATURE; |
reacts with |
HLA-DRA | NCI_NATURE; |
reacts with |
HLA-DRB1 | NCI_NATURE; |
reacts with |
LCK | NCI_NATURE; |
reacts with |
SH3BP2 | NCI_NATURE; |
reacts with |
SLA2 | NCI_NATURE; |
reacts with |
ZAP70 | NCI_NATURE; |
state change |
CD28 | NCI_NATURE; |
state change |
GNG2 | NCI_NATURE; |
state change |
PTPN6 | NCI_NATURE; |
state change |
RGS1 | NCI_NATURE; |