| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 2908 |
Name | NR3C1 |
Synonymous | GCCR|GCR|GR|GRL;nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor);NR3C1;nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
Definition | glucocorticoid nuclear receptor variant 1|glucocorticoid receptor|nuclear receptor subfamily 3 group C member 1 variant DL-1|nuclear receptor subfamily 3 group C member 1 variant NS-1 |
Position | 5q31.3 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
AR | NCI_NATURE; |
in same component |
HDAC6 | NCI_NATURE; |
in same component |
HSP90AA1 | NCI_NATURE; |
in same component |
SMAD4 | NCI_NATURE; |
interacts with |
ADA | BIOGRID; |
interacts with |
ADA | HPRD; |
interacts with |
AKT1 | HPRD; |
interacts with |
AR | HPRD; |
interacts with |
ARPC5 | BIOGRID; |
interacts with |
BAG1 | BIOGRID; |
interacts with |
BAG1 | HPRD; |
interacts with |
CALR | BIOGRID; |
interacts with |
CALR | HPRD; |
interacts with |
CD3D | MINT; |
interacts with |
CD4 | HPRD; |
interacts with |
CD4 | MINT; |
interacts with |
CEBPA | BIOGRID; |
interacts with |
CEBPA | HPRD; |
interacts with |
CEBPB | BIOGRID; |
interacts with |
CEBPB | HPRD; |
interacts with |
COPS6 | HPRD; |
interacts with |
CREB1 | BIOGRID; |
interacts with |
CREB1 | HPRD; |
interacts with |
CREBBP | BIOGRID; |
interacts with |
CREBBP | HPRD; |
interacts with |
DAP3 | BIOGRID; |
interacts with |
DAP3 | HPRD; |
interacts with |
DAXX | BIOGRID; |
interacts with |
DCAF6 | HPRD; |
interacts with |
DDX54 | BIOGRID; |
interacts with |
DDX54 | HPRD; |
interacts with |
DYNC1I2 | HPRD; |
interacts with |
ECD | BIOGRID; |
interacts with |
EP300 | BIOGRID; |
interacts with |
ETS1 | HPRD; |
interacts with |
ETS2 | BIOGRID; |
interacts with |
ETS2 | HPRD; |
interacts with |
FKBP4 | BIOGRID; |
interacts with |
FKBP4 | HPRD; |
interacts with |
FYN | HPRD; |
interacts with |
GRIP1 | BIOGRID; |
interacts with |
GRIP1 | HPRD; |
interacts with |
GRIP1 | MINT; |
interacts with |
HDAC1 | BIOGRID; |
interacts with |
HDAC2 | BIOGRID; |
interacts with |
HDAC6 | BIOGRID; |
interacts with |
HMGB1 | BIOGRID; |
interacts with |
HMGB2 | BIOGRID; |
interacts with |
HNRNPU | BIOGRID; |
interacts with |
HNRNPU | HPRD; |
interacts with |
HOXB1 | BIOGRID; |
interacts with |
HSP82 | BIOGRID; |
interacts with |
HSP90AA1 | BIOGRID; |
interacts with |
HSP90AA1 | HPRD; |
interacts with |
HSPD1 | BIOGRID; |
interacts with |
IFNGR2 | HPRD; |
interacts with |
JUN | BIOGRID; |
interacts with |
JUN | HPRD; |
interacts with |
KDM5A | BIOGRID; |
interacts with |
KDM5A | HPRD; |
interacts with |
KPNA2 | HPRD; |
interacts with |
LCK | HPRD; |
interacts with |
LCK | MINT; |
interacts with |
LRIF1 | BIOGRID; |
interacts with |
MAFF | BIOGRID; |
interacts with |
MAPK14 | HPRD; |
interacts with |
MAPK15 | HPRD; |
interacts with |
MAPK1 | HPRD; |
interacts with |
MAPK8 | HPRD; |
interacts with |
MDM2 | BIOGRID; |
interacts with |
MDM2 | HPRD; |
interacts with |
MED14 | BIOGRID; |
interacts with |
MED14 | HPRD; |
interacts with |
MED1 | BIOGRID; |
interacts with |
MED25 | MINT; |
interacts with |
MSX2 | BIOGRID; |
interacts with |
NCL | BIOGRID; |
interacts with |
NCOA1 | BIOGRID; |
interacts with |
NCOA1 | HPRD; |
interacts with |
NCOA2 | BIOGRID; |
interacts with |
NCOA2 | HPRD; |
interacts with |
NCOA3 | BIOGRID; |
interacts with |
NCOA4 | BIOGRID; |
interacts with |
NCOA6 | BIOGRID; |
interacts with |
NCOA6 | HPRD; |
interacts with |
NCOR1 | BIOGRID; |
interacts with |
NCOR1 | HPRD; |
interacts with |
NCOR2 | BIOGRID; |
interacts with |
NCOR2 | HPRD; |
interacts with |
NEDD4L | BIOGRID; |
interacts with |
NFKB1 | BIOGRID; |
interacts with |
NFKB1 | HPRD; |
interacts with |
NFKB2 | BIOGRID; |
interacts with |
NFKB2 | HPRD; |
interacts with |
NR2E3 | BIOGRID; |
interacts with |
NR2F2 | BIOGRID; |
interacts with |
NR2F2 | HPRD; |
interacts with |
NR2F6 | BIOGRID; |
interacts with |
NR2F6 | HPRD; |
interacts with |
NR3C2 | BIOGRID; |
interacts with |
NRIP1 | BIOGRID; |
interacts with |
NRIP1 | HPRD; |
interacts with |
ONECUT1 | BIOGRID; |
interacts with |
ONECUT1 | HPRD; |
interacts with |
PBX1 | BIOGRID; |
interacts with |
PBX1 | HPRD; |
interacts with |
PELP1 | BIOGRID; |
interacts with |
PELP1 | HPRD; |
interacts with |
PIAS2 | BIOGRID; |
interacts with |
POU1F1 | BIOGRID; |
interacts with |
POU1F1 | HPRD; |
interacts with |
POU2F1 | BIOGRID; |
interacts with |
POU2F1 | HPRD; |
interacts with |
POU2F2 | BIOGRID; |
interacts with |
POU2F2 | HPRD; |
interacts with |
PPARGC1A | BIOGRID; |
interacts with |
PPARGC1A | HPRD; |
interacts with |
PPID | HPRD; |
interacts with |
PPP5C | HPRD; |
interacts with |
PRKACA | HPRD; |
interacts with |
PRKDC | HPRD; |
interacts with |
PRPF6 | HPRD; |
interacts with |
Psmc3ip | BIOGRID; |
interacts with |
PSMC3IP | BIOGRID; |
interacts with |
PSMC3IP | HPRD; |
interacts with |
PTGES3 | BIOGRID; |
interacts with |
PTGES3 | HPRD; |
interacts with |
PTMS | BIOGRID; |
interacts with |
PTMS | HPRD; |
interacts with |
RAD9A | BIOGRID; |
interacts with |
RAF1 | BIOGRID; |
interacts with |
RAF1 | HPRD; |
interacts with |
RANBP9 | BIOGRID; |
interacts with |
RAN | BIOGRID; |
interacts with |
RBM14 | BIOGRID; |
interacts with |
RELA | BIOGRID; |
interacts with |
RELA | HPRD; |
interacts with |
RNF14 | HPRD; |
interacts with |
RPS6KA5 | MINT; |
interacts with |
RXRB | BIOGRID; |
interacts with |
SET | BIOGRID; |
interacts with |
SFN | BIOGRID; |
interacts with |
SFN | HPRD; |
interacts with |
SFN | MINT; |
interacts with |
SFPQ | BIOGRID; |
interacts with |
SLC25A4 | HPRD; |
interacts with |
SMARCA2 | BIOGRID; |
interacts with |
SMARCA4 | BIOGRID; |
interacts with |
SMARCC1 | BIOGRID; |
interacts with |
SMARCC2 | HPRD; |
interacts with |
SMARCD1 | BIOGRID; |
interacts with |
SMARCD1 | HPRD; |
interacts with |
SMARCE1 | BIOGRID; |
interacts with |
SMARCE1 | HPRD; |
interacts with |
SRC | BIOGRID; |
interacts with |
SRC | HPRD; |
interacts with |
STAT3 | BIOGRID; |
interacts with |
STAT3 | HPRD; |
interacts with |
STAT5A | HPRD; |
interacts with |
STAT5B | BIOGRID; |
interacts with |
STAT5B | HPRD; |
interacts with |
STIP1 | HPRD; |
interacts with |
STUB1 | BIOGRID; |
interacts with |
SUMO4 | HPRD; |
interacts with |
SVIL | BIOGRID; |
interacts with |
SYT1 | HPRD; |
interacts with |
TADA2A | BIOGRID; |
interacts with |
TBP | BIOGRID; |
interacts with |
TBP | HPRD; |
interacts with |
TDG | BIOGRID; |
interacts with |
TGFB1I1 | BIOGRID; |
interacts with |
TGFB1I1 | HPRD; |
interacts with |
TP53 | BIOGRID; |
interacts with |
TRIM24 | BIOGRID; |
interacts with |
TRIM24 | HPRD; |
interacts with |
TRIM28 | BIOGRID; |
interacts with |
TRIM28 | HPRD; |
interacts with |
TSG101 | BIOGRID; |
interacts with |
TSG101 | HPRD; |
interacts with |
TXN | BIOGRID; |
interacts with |
TXN | HPRD; |
interacts with |
UBE2I | HPRD; |
interacts with |
YWHAH | BIOGRID; |
interacts with |
YWHAH | HPRD; |
interacts with |
ZBTB16 | BIOGRID; |
interacts with |
ZBTB16 | HPRD; |
interacts with |
ZBTB20 | BIOGRID; |
interacts with |
ZBTB3 | BIOGRID; |
interacts with |
ZBTB9 | BIOGRID; |
interacts with |
ZNF496 | BIOGRID; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
FOS | NCI_NATURE; |
metabolic catalysis |
JUN | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
AR | NCI_NATURE; |
reacts with |
HDAC6 | NCI_NATURE; |
reacts with |
HSP90AA1 | NCI_NATURE; |
reacts with |
NFKB1 | NCI_NATURE; |
reacts with |
NR3C1 | NCI_NATURE; |
reacts with |
RELA | NCI_NATURE; |
reacts with |
SMAD4 | NCI_NATURE; |