| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 2065 |
Name | ERBB3 |
Synonymous | ErbB-3|HER3|LCCS2|MDA-BF-1|c-erbB-3|c-erbB3|erbB3-S|p180-ErbB3|p45-sErbB3|p85-sErbB3;v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian);ERBB3;v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) |
Definition | proto-oncogene-like protein c-ErbB-3|receptor tyrosine-protein kinase erbB-3|tyrosine kinase-type cell surface receptor HER3 |
Position | 12q13 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
AREG | NCI_NATURE; |
in same component |
EGF | NCI_NATURE; |
in same component |
EGFR | NCI_NATURE; |
in same component |
ERBB2 | NCI_NATURE; |
in same component |
EREG | NCI_NATURE; |
in same component |
NRG2 | NCI_NATURE; |
in same component |
SHC1 | NCI_NATURE; |
in same component |
SOS1 | NCI_NATURE; |
in same component |
TGFA | NCI_NATURE; |
interacts with |
ABL1 | MINT; |
interacts with |
ABL2 | MINT; |
interacts with |
CD82 | BIOGRID; |
interacts with |
CHN2 | MINT; |
interacts with |
CRK | MINT; |
interacts with |
CRKL | MINT; |
interacts with |
CSK | BIOGRID; |
interacts with |
CSK | MINT; |
interacts with |
DAB1 | MINT; |
interacts with |
DAPP1 | MINT; |
interacts with |
EGF | BIOGRID; |
interacts with |
EGFR | BIOGRID; |
interacts with |
EGFR | INTACT; |
interacts with |
EGR1 | BIOGRID; |
interacts with |
ERBB2 | BIOGRID; |
interacts with |
ERBB2 | INTACT; |
interacts with |
FER | MINT; |
interacts with |
FGFR1 | MINT; |
interacts with |
GRB7 | BIOGRID; |
interacts with |
GRB7 | MINT; |
interacts with |
HCK | MINT; |
interacts with |
HDAC6 | BIOGRID; |
interacts with |
IL6ST | BIOGRID; |
interacts with |
ITK | MINT; |
interacts with |
JAK2 | MINT; |
interacts with |
JAK3 | MINT; |
interacts with |
LRIG1 | BIOGRID; |
interacts with |
MUC1 | BIOGRID; |
interacts with |
NCK1 | MINT; |
interacts with |
NCK2 | MINT; |
interacts with |
NRG1 | BIOGRID; |
interacts with |
NRG2 | BIOGRID; |
interacts with |
ODF2L | BIOGRID; |
interacts with |
PA2G4 | BIOGRID; |
interacts with |
PIK3R1 | BIOGRID; |
interacts with |
PIK3R1 | INTACT; |
interacts with |
PIK3R1 | MINT; |
interacts with |
PIK3R2 | BIOGRID; |
interacts with |
PIK3R2 | MINT; |
interacts with |
PIK3R3 | MINT; |
interacts with |
PLCG1 | MINT; |
interacts with |
PTK6 | BIOGRID; |
interacts with |
PTK6 | MINT; |
interacts with |
RASA1 | MINT; |
interacts with |
RASA4 | MINT; |
interacts with |
RGS4 | BIOGRID; |
interacts with |
RIN1 | MINT; |
interacts with |
RNF41 | BIOGRID; |
interacts with |
RPN1 | BIOGRID; |
interacts with |
SH2B3 | MINT; |
interacts with |
SH2D1A | MINT; |
interacts with |
Shc1 | BIOGRID; |
interacts with |
SHC1 | BIOGRID; |
interacts with |
SHC1 | MINT; |
interacts with |
SHC3 | MINT; |
interacts with |
SRC | MINT; |
interacts with |
SYK | MINT; |
interacts with |
TENC1 | MINT; |
interacts with |
TNS3 | MINT; |
interacts with |
TNS4 | MINT; |
interacts with |
TXK | MINT; |
interacts with |
VAV2 | MINT; |
interacts with |
VAV3 | MINT; |
interacts with |
ZAP70 | MINT; |
interacts with |
ZNF207 | BIOGRID; |
Metabolic Interaction [Top] | ||
There is no record for ERBB3 | ||
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
AREG | NCI_NATURE; |
reacts with |
EGF | NCI_NATURE; |
reacts with |
EGFR | NCI_NATURE; |
reacts with |
ERBB2 | NCI_NATURE; |
reacts with |
ERBB3 | NCI_NATURE; |
reacts with |
EREG | NCI_NATURE; |
reacts with |
HSP90AA1 | NCI_NATURE; |
reacts with |
ITGA6 | NCI_NATURE; |
reacts with |
ITGB4 | NCI_NATURE; |
reacts with |
NRG2 | NCI_NATURE; |
reacts with |
SHC1 | NCI_NATURE; |
reacts with |
SOS1 | NCI_NATURE; |
reacts with |
TGFA | NCI_NATURE; |
state change |
PRKACA | NCI_NATURE; |
state change |
PTPN11 | NCI_NATURE; |
state change |
RNF41 | NCI_NATURE; |