| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 7132 |
Name | TNFRSF1A |
Synonym | CD120a|FPF|TBP1|TNF-R|TNF-R-I|TNF-R55|TNFAR|TNFR1|TNFR55|TNFR60|p55|p55-R|p60;tumor necrosis factor receptor superfamily, member 1A;TNFRSF1A;tumor necrosis factor receptor superfamily, member 1A |
Definition | TNF-R1|TNF-RI|TNFR-I|tumor necrosis factor binding protein 1|tumor necrosis factor receptor 1A isoform beta|tumor necrosis factor receptor superfamily member 1A|tumor necrosis factor receptor type 1|tumor necrosis factor-alpha receptor |
Position | 12p13.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Adipocytokine signaling pathway;KEGG PATHWAY;hsa04920 |
Pathway | Chagas disease;KEGG PATHWAY;hsa05142 |
Pathway | TNF receptor signaling pathway;PID Curated;200086 |
Pathway | Ceramide signaling pathway;PID Curated;200100 |
Pathway | Apoptosis;Reactome;REACT:578 |
Pathway | Apoptosis;KEGG PATHWAY;hsa04210 |
Pathway | tnfr1 signaling pathway;PID BioCarta;100015 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Pathway | Signaling events mediated by HDAC Class I;PID Curated;200070 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | keratinocyte differentiation;PID BioCarta;100119 |
Pathway | HIV-1 Nef: Negative effector of Fas and TNF-alpha;PID Curated;200133 |
Pathway | Amyotrophic lateral sclerosis (ALS);KEGG PATHWAY;hsa05014 |
Pathway | Apoptosis signaling pathway;PANTHER;P00006 |
Pathway | Canonical NF-kappaB pathway;PID Curated;200026 |
Pathway | Alzheimer's disease;KEGG PATHWAY;hsa05010 |
Pathway | Caspase cascade in apoptosis;PID Curated;200148 |
Pathway | Hepatitis C;KEGG PATHWAY;hsa05160 |
Pathway | TNF signaling;PID Reactome;500256 |
Pathway | Toxoplasmosis;KEGG PATHWAY;hsa05145 |
Pathway | tnf/stress related signaling;PID BioCarta;100026 |
Disease | obesity PAI-1 levels;GAD |
Disease | lymphoma;GAD |
Disease | thrombosis, deep vein;GAD |
Disease | amyloidosis;GAD |
Disease | Multiple sclerosis;NHGRI |
Disease | lung cancer;GAD |
Disease | IMMUNE;GAD |
Disease | tuberculosis tumor necrosis factor-alpha;GAD |
Disease | METABOLIC;GAD |
Disease | rheumatoid arthritis;GAD |
Disease | INFECTION;GAD |
Disease | diabetes, type 2;GAD |
Disease | diabetes, type 1;GAD |
Disease | Tumor necrosis factor receptor-associated periodic syndrome;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | cystic fibrosis;GAD |
Disease | CANCER;GAD |
Disease | Crohn's disease;GAD |
Disease | carotid intima-media thickness;GAD |
Disease | Behcet's Disease;GAD |
Disease | Periodic fever, familial;OMIM |
Disease | multiple sclerosis;GAD |
Disease | ulcerative colitis;GAD |
Disease | myocardial infarct;GAD |
External Links | |
Links to Entrez Gene | 7132 |
Links to all GeneRIF Items | 7132 |
Links to iHOP | 7132 |
Sequence Information | |
Nucleotide Sequence | >7132 : length: 1368 atgggcctctccaccgtgcctgacctgctgctgccactggtgctcctggagctgttggtg ggaatatacccctcaggggttattggactggtccctcacctaggggacagggagaagaga gatagtgtgtgtccccaaggaaaatatatccaccctcaaaataattcgatttgctgtacc aagtgccacaaaggaacctacttgtacaatgactgtccaggcccggggcaggatacggac tgcagggagtgtgagagcggctccttcaccgcttcagaaaaccacctcagacactgcctc agctgctccaaatgccgaaaggaaatgggtcaggtggagatctcttcttgcacagtggac cgggacaccgtgtgtggctgcaggaagaaccagtaccggcattattggagtgaaaacctt ttccagtgcttcaattgcagcctctgcctcaatgggaccgtgcacctctcctgccaggag aaacagaacaccgtgtgcacctgccatgcaggtttctttctaagagaaaacgagtgtgtc tcctgtagtaactgtaagaaaagcctggagtgcacgaagttgtgcctaccccagattgag aatgttaagggcactgaggactcaggcaccacagtgctgttgcccctggtcattttcttt ggtctttgccttttatccctcctcttcattggtttaatgtatcgctaccaacggtggaag tccaagctctactccattgtttgtgggaaatcgacacctgaaaaagagggggagcttgaa ggaactactactaagcccctggccccaaacccaagcttcagtcccactccaggcttcacc cccaccctgggcttcagtcccgtgcccagttccaccttcacctccagctccacctatacc cccggtgactgtcccaactttgcggctccccgcagagaggtggcaccaccctatcagggg gctgaccccatccttgcgacagccctcgcctccgaccccatccccaacccccttcagaag tgggaggacagcgcccacaagccacagagcctagacactgatgaccccgcgacgctgtac gccgtggtggagaacgtgcccccgttgcgctggaaggaattcgtgcggcgcctagggctg agcgaccacgagatcgatcggctggagctgcagaacgggcgctgcctgcgcgaggcgcaa tacagcatgctggcgacctggaggcggcgcacgccgcggcgcgaggccacgctggagctg ctgggacgcgtgctccgcgacatggacctgctgggctgcctggaggacatcgaggaggcg ctttgcggccccgccgccctcccgcccgcgcccagtcttctcagatga |
Protein Sequence | >7132 : length: 455 MGLSTVPDLLLPLVLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCT KCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVD RDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENECV SCSNCKKSLECTKLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRYQRWK SKLYSIVCGKSTPEKEGELEGTTTKPLAPNPSFSPTPGFTPTLGFSPVPSSTFTSSSTYT PGDCPNFAAPRREVAPPYQGADPILATALASDPIPNPLQKWEDSAHKPQSLDTDDPATLY AVVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLEL LGRVLRDMDLLGCLEDIEEALCGPAALPPAPSLLR |